Search Results - "Laforet, G"

A novel clinical trial design to evaluate the efficacy and safety of two exon-skipping PMOs, SRP-4045 and SRP-4053, in patients with Duchenne muscular dystrophy by Laforet, G, Kaye, E, Saoud, J

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Predictors of disease severity and progression in patients with Duchenne muscular dystrophy: A literature review by Eliopoulos, H, Laforet, G, Narayana, A, Lucas, K, Duda, P

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P169 – 2697: A novel clinical trial design to evaluate the efficacy and safety of two exon-skipping drugs, SRP-4045 and SRP-4053, in a master protocol for patients with Duchenne muscular dystrophy (DMD) by Saoud, J, Kaye, E.M, Laforet, G

“…Background DMD, an X-linked myopathy caused by mutations in the DMD gene, results in the inability to produce functional dystrophin, an essential protein for…”
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Changes in Cortical and Striatal Neurons Predict Behavioral and Electrophysiological Abnormalities in a Transgenic Murine Model of Huntington's Disease by Laforet, Genevieve A, Sapp, Ellen, Chase, Kathryn, McIntyre, Charmian, Boyce, Frederick M, Campbell, Mary, Cadigan, Beth A, Warzecki, Lori, Tagle, Danilo A, Reddy, P. Hemachandra, Cepeda, Carlos, Calvert, Christopher R, Jokel, Eve S, Klapstein, Gloria J, Ariano, Marjorie A, Levine, Michael S, DiFiglia, Marian, Aronin, Neil

“…Neurons in Huntington's disease exhibit selective morphological and subcellular alterations in the striatum and cortex. The link between these neuronal changes…”
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Movement monitoring at home and during study visits identifies sources of variability in 6MWT performance in Duchenne muscular dystrophy by Servais, L, Grelet, M, Seferian, A, Gasnier, E, Gargaun, E, Straub, V, Mercuri, E, Voit, T, Laforet, G, Dorveau, E, Vissiere, D, Muntoni, F

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Longitudinal results of magneto-inertial motion analysis in Duchenne muscular dystrophy ambulant patients by Seferian, A, Gargaun, E, Grelet, M, Gasnier, E, Lilien, C, Gillabert, S, Duchene, D, Voit, T, Domingos, J. Piscos, Guglieri, M, Straub, V, Leone, D, Mercuri, E, Laforet, G, Muntoni, F, Dorveaux, E, Vissiere, D, Servais, L

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Forskolin and dopamine D1 receptor activation increase huntingtin's association with endosomes in immortalized neuronal cells of striatal origin by KIM, M, VELIER, J, CHASE, K, LAFORET, G, KALCHMAN, M. A, HAYDEN, M. R, WON, L, HELLER, A, ARONIN, N, DIFIGLIA, M

“…Huntingtin is a cytoplasmic protein of unknown function that associates with vesicle membranes and microtubules. Its protein interactions suggest that…”
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G.P.259 - A novel clinical trial design to evaluate the efficacy and safety of two exon-skipping PMOs, SRP-4045 and SRP-4053, in patients with Duchenne muscular dystrophy by Laforet, G., Kaye, E., Saoud, J.

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Functional limits of conformation, hydrophobicity, and steric constraints in prokaryotic signal peptide cleavage regions. Wild type transport by a simple polymeric signal sequence by Laforet, G A, Kendall, D A

“…These experiments examine the role of conformation, hydrophobicity, and steric constraints in the function of the prokaryotic signal peptide cleavage region…”
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Does Change in Patient-Reported QOL Correlate with Change in Other Clinical and MRI Measures in Early MS? Analysis of the 10-Year CHAMPIONS Cohort (P07.100) by Kinkel, R., Laforet, G., You, X.

“…Abstract only…”
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Identifying Patients with Relapsing-Remitting Multiple Sclerosis Who Have Aggressive Disease Characterized by Rapid Disability Progression (P05.093) by Scott, T., Laforet, G., You, X.

“…Abstract only…”
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Peptide and Protein Synthesis by Segment Synthesis-Condensation by Kaiser, Emil Thomas, Mihara, Hisakazu, Laforet, Genevieve A., Kelly, Jeffery W., Walters, Lee, Findeis, Mark A., Sasaki, Tomikazu

“…The chemical synthesis of biologically active peptides and polypeptides can be achieved by using a convergent strategy of condensing protected peptide segments…”
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A.O.10 - Movement monitoring at home and during study visits identifies sources of variability in 6MWT performance in Duchenne muscular dystrophy by Servais, L., Grelet, M., Seferian, A., Gasnier, E., Gargaun, E., Straub, V., Mercuri, E., Voit, T., Laforet, G., Dorveau, E., Vissiere, D., Muntoni, F.

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Signal peptide subsegments are not always functionally interchangeable. M13 procoat hydrophobic core fails to transport alkaline phosphatase in Escherichia coli by LAFORET, G. A, KAISER, E. T, KENDALL, D. A

“…Bacterial signal peptides display little amino acid sequence homology despite their shared role in mediating protein transport. This heterogeneity may exist to…”
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P.328 - Longitudinal results of magneto-inertial motion analysis in Duchenne muscular dystrophy ambulant patients by Seferian, A., Gargaun, E., Grelet, M., Gasnier, E., Lilien, C., Gillabert, S., Duchene, D., Voit, T., Domingos, J. Piscos, Guglieri, M., Straub, V., Leone, D., Mercuri, E., Laforet, G., Muntoni, F., Dorveaux, E., Vissiere, D., Servais, L.

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The Fiction of Informed Consent by Laforet, Eugene G

“…FEW FABRICATED concepts of recent vintage have achieved the currency, uncritical and ungrudging, of "informed consent." The term is so semantically felicitous,…”
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Mutant Huntingtin Expression in Clonal Striatal Cells: Dissociation of Inclusion Formation and Neuronal Survival by Caspase Inhibition by Kim, Manho, Lee, H-S, LaForet, Genevieve, McIntyre, Charmian, Martin, Eileen J, Chang, Patrick, Kim, Tae Wan, Williams, M, Reddy, P. H, Tagle, Dan, Boyce, Frederick M, Won, Lisa, Heller, Alfred, Aronin, Neil, DiFiglia, Marian

“…Neuronal intranuclear inclusions are found in the brains of patients with Huntington's disease and form from the polyglutamine-expanded N-terminal region of…”
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Cecil Coggins and the War in the Shadows by Laforet, Eugene G

“…THIS precept—as sincere as it was moralistic, as forthright as it was naive—verbalized, epitomized, and, to a certain extent, reinforced the American attitude…”
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Are There Multiple Pathways in the Pathogenesis of Huntington's Disease? by Aronin, Neil, Kim, Manho, Laforet, Genevieve, DiFiglia, Marian

“…Studies of huntingtin localization in human post-mortem brain offer insights and a framework for basic experiments in the pathogenesis of Huntington's disease…”
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Carcinoma obstructing the trachea. Treatment by laser resection by Laforet, E G, Berger, R L, Vaughan, C W

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