Search Results - "Lafon, Stephen W."

Adverse Events Associated with Trimethoprim-Sulfamethoxazole and Atovaquone during the Treatment of AIDS-Related Pneumocystis carinii Pneumonia by Hughes, Walter T., LaFon, Stephen W., Scott, Janna D., Masur, Henry

“…Atovaquone was compared to trimethoprim-sulfamethoxazole (TMP-SMZ) for the relationship of time receiving therapy, plasma drug concentrations, and incidence of…”
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Atovaquone Suspension in HIV-Infected Volunteers: Pharmacokinetics, Pharmacodynamics, and TMP-SMX Interaction Study by Falloon, Judith, Sargent, Susie, Piscitelli, Stephen C., Bechtel, Christine, LaFon, Stephen W., Sadler, Brian, Walker, Robert E., Kovacs, Joseph A., Polis, Michael A., Davey Jr, Richard T., Lane, H. Clifford, Masur, Henry

“…Study Objective. To evaluate the pharmacokinetics and safety of atovaquone suspension in volunteers infected with the human immunodeficiency virus ((HIV)…”
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Prophylactically Administered Retrovir® in Health Care Workers Potentially Exposed to the Human Immunodeficiency Virus by Lafon, Stephen W., Lehrman, Sandra Nusinoff, Barry, David W.

“…On 29 April 1988, Burroughs Wellcome initiated a double-blind, placebo-controlled trial in the United States to evaluate the potential effectiveness of…”
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Antiprotozoal activity of 3'-deoxyinosine. Inverse correlation to cleavage of the glycosidic bond by Moorman, A R, LaFon, S W, Nelson, D J, Carter, H H, Marr, J J, Berens, R L

“…Two nucleosides related to the known antiprotozoal agent 1-(beta-D-ribofuranosyl)-1,5-dihydro-4H-pyrazolo-[3,4-d]pyrimidine-4-one (allopurinol riboside, 1)…”
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Antileishmanial effect of allopurinol and allopurinol ribonucleoside on intracellular forms of Leishmania donovani by Berens, R L, Marr, J J, Nelson, D J, LaFon, S W

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6-THIOPURINE RIBOSIDE ANALOGS: THEIR TOXICITY AND METABOLISM IN LEISHMANIA DONOVANI AND MAMMALIAN CELLS: 107 by Lafon, Stephen W, Cohn, Naomi K, Nelson, Donald J, Berens, Randolph L

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Purine metabolism in Trypanosoma cruzi by Berens, R L, Marr, J J, LaFon, S W, Nelson, D J

“…Culture forms of Trypanosoma cruzi are incapable of synthesizing purines de novo from formate, glycine, or serine and require an exogenous purine for growth…”
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Antigiardial activity of guanine arabinoside. Mechanism studies by Miller, R L, Nelson, D J, LaFon, S W, Miller, W H, Krenitsky, T A

“…Guanine arabinoside (araG) inhibited the in vitro growth of Giardia lamblia WB with an ED50 value of 4 microM. The inhibition was prevented completely by…”
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Purine and pyrimidine salvage pathways in Leishmania donovani by LaFon, S W, Nelson, D J, Berens, R L, Marr, J J

“…Leishmania donovani, grown in culture, salvaged radiolabeled purine bases which were distributed into adenine and guanine ribonucleotides and into the RNA of…”
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The metabolism of formycin B in Leishmania donovani by Nelson, D J, Lafon, S W, Jones, T E, Spector, T, Berens, R L, Marr, J J

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Monophosphates of formycin B and allopurinol riboside. Interactions with leishmanial and mammalian succino-AMP synthetase and GMP reductase by Spector, T, Jones, T E, LaFon, S W, Nelson, D J, Berens, R L, Marr, J J

“…Formycin B 5'-monophosphate (Form B-MP) and allopurinol riboside 5'-monophosphate ( HPPR -MP) are isomers of IMP that are metabolically produced when…”
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Purine metabolism in the intact sporozoites and merozoites of Eimeria tenella by LaFon, S W, Nelson, D J

“…Intact Eimeria tenella sporozoites and merozoites did not incorporate radiolabeled formate or glycine into their purine nucleotides suggesting a lack of de…”
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Antileishmanial action of 4-thiopyrazolo (3.4-d) pyrimidine and its ribonucleoside. Biological effects and metabolism by Marr, J J, Berens, R L, Nelson, D J, Krenitsky, T A, Spector, T, LaFon, S W, Elion, G B

“…Thiopurinol [4-thiopyrazolo(3.4-dyprimidine, TPP] and its ribonucleoside (TPPR) were effective in vitro against the intracellular and extracellular forms of L…”
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6-Thiopurine riboside analogs: their toxicity and metabolism in Leishmania donovani and mammalian cells by LaFon, S W, Cohn, N K, Nelson, D J, Berens, R L

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