Search Results - "Lafon, Stephen W"
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Adverse Events Associated with Trimethoprim-Sulfamethoxazole and Atovaquone during the Treatment of AIDS-Related Pneumocystis carinii Pneumonia
Published in The Journal of infectious diseases (01-05-1995)“…Atovaquone was compared to trimethoprim-sulfamethoxazole (TMP-SMZ) for the relationship of time receiving therapy, plasma drug concentrations, and incidence of…”
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Atovaquone Suspension in HIV-Infected Volunteers: Pharmacokinetics, Pharmacodynamics, and TMP-SMX Interaction Study
Published in Pharmacotherapy (01-09-1999)“…Study Objective. To evaluate the pharmacokinetics and safety of atovaquone suspension in volunteers infected with the human immunodeficiency virus ((HIV)…”
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Prophylactically Administered Retrovir® in Health Care Workers Potentially Exposed to the Human Immunodeficiency Virus
Published in The Journal of infectious diseases (01-08-1988)“…On 29 April 1988, Burroughs Wellcome initiated a double-blind, placebo-controlled trial in the United States to evaluate the potential effectiveness of…”
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Antiprotozoal activity of 3'-deoxyinosine. Inverse correlation to cleavage of the glycosidic bond
Published in Biochemical pharmacology (05-07-1991)“…Two nucleosides related to the known antiprotozoal agent 1-(beta-D-ribofuranosyl)-1,5-dihydro-4H-pyrazolo-[3,4-d]pyrimidine-4-one (allopurinol riboside, 1)…”
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Antileishmanial effect of allopurinol and allopurinol ribonucleoside on intracellular forms of Leishmania donovani
Published in Biochemical pharmacology (01-09-1980)Get more information
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6-THIOPURINE RIBOSIDE ANALOGS: THEIR TOXICITY AND METABOLISM IN LEISHMANIA DONOVANI AND MAMMALIAN CELLS: 107
Published in Pediatric research (01-07-1985)Get full text
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Purine metabolism in Trypanosoma cruzi
Published in Molecular and biochemical parasitology (01-01-1981)“…Culture forms of Trypanosoma cruzi are incapable of synthesizing purines de novo from formate, glycine, or serine and require an exogenous purine for growth…”
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Antigiardial activity of guanine arabinoside. Mechanism studies
Published in Biochemical pharmacology (01-08-1987)“…Guanine arabinoside (araG) inhibited the in vitro growth of Giardia lamblia WB with an ED50 value of 4 microM. The inhibition was prevented completely by…”
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Purine and pyrimidine salvage pathways in Leishmania donovani
Published in Biochemical pharmacology (01-01-1982)“…Leishmania donovani, grown in culture, salvaged radiolabeled purine bases which were distributed into adenine and guanine ribonucleotides and into the RNA of…”
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The metabolism of formycin B in Leishmania donovani
Published in Biochemical and biophysical research communications (16-09-1982)Get more information
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Monophosphates of formycin B and allopurinol riboside. Interactions with leishmanial and mammalian succino-AMP synthetase and GMP reductase
Published in Biochemical pharmacology (15-05-1984)“…Formycin B 5'-monophosphate (Form B-MP) and allopurinol riboside 5'-monophosphate ( HPPR -MP) are isomers of IMP that are metabolically produced when…”
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Purine metabolism in the intact sporozoites and merozoites of Eimeria tenella
Published in Molecular and biochemical parasitology (01-01-1985)“…Intact Eimeria tenella sporozoites and merozoites did not incorporate radiolabeled formate or glycine into their purine nucleotides suggesting a lack of de…”
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Antileishmanial action of 4-thiopyrazolo (3.4-d) pyrimidine and its ribonucleoside. Biological effects and metabolism
Published in Biochemical pharmacology (15-01-1982)“…Thiopurinol [4-thiopyrazolo(3.4-dyprimidine, TPP] and its ribonucleoside (TPPR) were effective in vitro against the intracellular and extracellular forms of L…”
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