Search Results - "Laflin, Amy D"

Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses by Banach, Bailey B., Cerutti, Gabriele, Fahad, Ahmed S., Shen, Chen-Hsiang, Oliveira De Souza, Matheus, Katsamba, Phinikoula S., Tsybovsky, Yaroslav, Wang, Pengfei, Nair, Manoj S., Huang, Yaoxing, Francino-Urdániz, Irene M., Steiner, Paul J., Gutiérrez-González, Matías, Liu, Lihong, López Acevedo, Sheila N., Nazzari, Alexandra F., Wolfe, Jacy R., Luo, Yang, Olia, Adam S., Teng, I-Ting, Yu, Jian, Zhou, Tongqing, Reddem, Eswar R., Bimela, Jude, Pan, Xiaoli, Madan, Bharat, Laflin, Amy D., Nimrania, Rajani, Yuen, Kwok-Yung, Whitehead, Timothy A., Ho, David D., Kwong, Peter D., Shapiro, Lawrence, DeKosky, Brandon J.

“…Understanding mechanisms of protective antibody recognition can inform vaccine and therapeutic strategies against SARS-CoV-2. We report a monoclonal antibody,…”
Get full text

Cell activation-based screening of natively paired human T cell receptor repertoires by Fahad, Ahmed S., Chung, Cheng Yu, López Acevedo, Sheila N., Boyle, Nicoleen, Madan, Bharat, Gutiérrez-González, Matías F., Matus-Nicodemos, Rodrigo, Laflin, Amy D., Ladi, Rukmini R., Zhou, John, Wolfe, Jacy, Llewellyn-Lacey, Sian, Koup, Richard A., Douek, Daniel C., Balfour, Henry H., Price, David A., DeKosky, Brandon J.

“…Adoptive immune therapies based on the transfer of antigen-specific T cells have been used successfully to treat various cancers and viral infections, but…”
Get full text

Stem Cells in Aggregate Form to Enhance Chondrogenesis in Hydrogels by Sridharan, BanuPriya, Lin, Staphany M, Hwu, Alexander T, Laflin, Amy D, Detamore, Michael S

“…There are a variety of exciting hydrogel technologies being explored for cartilage regenerative medicine. Our overall goal is to explore whether using stem…”
Get full text

Optimized Production of Fc Fusion Proteins by Sortase Enzymatic Ligation by Apley, Kyle D, Laflin, Amy D, Johnson, Stephanie N, Batrash, Noora, Griffin, J. Daniel, Berkland, Cory J, DeKosky, Brandon J

“…Fc fusions are a growing class of drugs comprising an antibody Fc domain covalently linked to a protein or peptide and can pose manufacturing challenges. In…”
Get full text

Immortalization and functional screening of natively paired human T cell receptor repertoires by Fahad, Ahmed S, Chung, Cheng-Yu, Lopez Acevedo, Sheila N, Boyle, Nicoleen, Madan, Bharat, Gutiérrez-González, Matias F, Matus-Nicodemos, Rodrigo, Laflin, Amy D, Ladi, Rukmini R, Zhou, John, Wolfe, Jacy, Llewellyn-Lacey, Sian, Koup, Richard A, Douek, Daniel C, Balfour Jr, Henry H, Price, David A, DeKosky, Brandon J

“…Abstract Functional analyses of the T cell receptor (TCR) landscape can reveal critical information about protection from disease and molecular responses to…”
Get full text

In vivo evaluation of stem cell aggregates on osteochondral regeneration by Sridharan, BanuPriya, Laflin, Amy D., Holtz, Michael A., Pacicca, Donna M., Wischmeier, Nicholas K., Detamore, Michael S.

“…ABSTRACT To date, many osteochondral regenerative approaches have utilized varied combinations of biocompatible materials and cells to engineer cartilage. Even…”
Get full text

Generating Chondromimetic Mesenchymal Stem Cell Spheroids by Regulating Media Composition and Surface Coating by Sridharan, BanuPriya, Laflin, Amy D., Detamore, Michael S.

“…Introduction Spheroids of mesenchymal stem cells (MSCs) in cartilage tissue engineering have been shown to enhance regenerative potential owing to their 3D…”
Get full text

Microsphere-Based Osteochondral Scaffolds Carrying Opposing Gradients Of Decellularized Cartilage And Demineralized Bone Matrix by Gupta, Vineet, Lyne, Dina V, Laflin, Amy D, Zabel, Taylor A, Barragan, Marilyn, Bunch, Joshua T, Pacicca, Donna M, Detamore, Michael S

“…Extracellular matrix (ECM) “raw materials” such as demineralized bone matrix (DBM) and cartilage matrix have emerged as leading scaffolding materials for…”
Get full text

In vivo evaluation of stem cell aggregates on osteochondral regeneration: IN VIVO EVALUATION OF STEM CELL AGGREGATES by Sridharan, BanuPriya, Laflin, Amy D., Holtz, Michael A., Pacicca, Donna M., Wischmeier, Nicholas K., Detamore, Michael S.

Get full text

Stem Cells in Aggregate Form to Enhance Chondrogenesis in Hydrogels: e0141479 by Sridharan, BanuPriya, Lin, Staphany M, Hwu, Alexander T, Laflin, Amy D, Detamore, Michael S

“…There are a variety of exciting hydrogel technologies being explored for cartilage regenerative medicine. Our overall goal is to explore whether using stem…”
Get full text