Search Results - "Laflamme, Karina"

Functional Analysis of a Novel cis-Acting Regulatory Region within the Human Ankyrin Gene (ANK-1) Promoter by Laflamme, Karina, Owen, Ashley N., Devlin, Emily E., Yang, Mary Q., Wong, Clara, Steiner, Laurie A., Garrett, Lisa J., Elnitski, Laura, Gallagher, Patrick G., Bodine, David M.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Polyphenols modulate calcium-independent mechanisms in human arterial tissue-engineered vascular media by Diebolt, Myriam, PhD, Laflamme, Karina, PhD, Labbé, Raymond, MD, FRCS(C), Auger, François A., MD, FRCP(C), Germain, Lucie, PhD, Andriantsitohaina, Ramaroson, PhD

“…Background In the present study, an arterial tissue-engineered vascular media (TEVM) was produced from cultured human smooth muscle cells of the umbilical…”
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Genome-wide detection of a TFIID localization element from an initial human disease mutation by Yang, Mary Q, Laflamme, Karina, Gotea, Valer, Joiner, Clinton H, Seidel, Nancy E, Wong, Clara, Petrykowska, Hanna M, Lichtenberg, Jens, Lee, Stephen, Welch, Lonnie, Gallagher, Patrick G, Bodine, David M, Elnitski, Laura

“…Eukaryotic core promoters are often characterized by the presence of consensus motifs such as the TATA box or initiator elements, which attract and direct the…”
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Adventitia contribution in vascular tone: insights from adventitia-derived cells in a tissue-engineered human blood vessel by Laflamme, Karina, Roberge, Charles J, Grenier, Guillaume, Rémy-Zolghadri, Murielle, Pouliot, Stéphanie, Baker, Kathleen, Labbé, Raymond, D'Orléans-Juste, Pédro, Auger, François A, Germain, Lucie

“…Whether the adventitia component of blood vessels directly participates in the regulation of vascular tone remains to be demonstrated. We have recently…”
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Local and Distant Elements Regulate Tissue-Specific Expression of ANK-1 Gene Transcripts by Owen, Ashley N., Laflamme, Karina, Pilon, Andre M., Garrett, Lisa J., Gallagher, Patrick G., Bodine, David M.

“…Fewer than 20,000 protein-coding genes in the human genome generate more than 100,000 proteins. This diversity results from the selective use of alternative…”
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Identification of a TFIID Binding Sequence That Increases Expression from the Ankyrin-1 Promoter: Application to Globin Gene Therapy by Laflamme, Karina, Elnitski, Laura E., Wong, Clara, Mary, Yang, Gallagher, Patrick G., Bodine, David M.

“…Effective Gene Therapy of the hemoglobin β-chain disorders β-thalassemia or Sickle Cell Disease (SCD), requires that viral vectors deliver β-like globin gene…”
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Identification of a Novel Core Promoter Element That Enhances Transcription: Application to Ankyrin Promoters for Globin Gene Therapy by Laflamme, Karina, Elnitski, Laura, Owen, Ashley N., Gallagher, Patrick G., Bodine, David M.

“…Gene Therapy for the hemoglobin β-chain disorders, Sickle Cell Disease (SCD) or beta thalassemia (β-thal), requires both efficient globin gene transfer into…”
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Tissue-engineered human vascular media with a functional endothelin system by LAFLAMME, Karina, ROBERGE, Charles J, LABONTE, Julie, POULIOT, Stéphanie, D'ORLEANS-JUSTE, Pédro, AUGER, Francois A, GERMAIN, Lucie

“…Cardiovascular diseases remain a major cause of death and disability in the Western world. Among the various approaches adopted to counteract the morbidity…”
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A 200 kb Survey of Chromatin in the ANK-1 Locus Demonstrates an Erythroid-Specific Chromatin Hub That Activates the Erythrocyte Ankyrin (ANK-1E) Promoter by Owen, Ashley N., Wolfsberg, Tyra, Laflamme, Karina, Wong, Clara, Maksimova, Yelena, Elnitski, Laura, Gallagher, Patrick G., Bodine, David M.

“…Mammals express a variety of erythroid and nonerythroid ankyrin-1 isoforms generated by alternate mRNA splicing and by expression from promoters upstream of 3…”
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Immunohistochemical localization of type 2 inositol 1,4,5-trisphosphate receptor to the nucleus of different mammalian cells by Laflamme, Karina, Domingue, Olivier, Guillemette, Benoit I., Guillemette, Gaétan

“…The inositol 1,4,5‐trisphosphate receptor (InsP3R) is a ligand‐gated Ca2+ channel responsible for the release of Ca2+ from intracellular stores in the response…”
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Thiol-reactive agents biphasically regulate inositol 1,4,5-trisphosphate binding and Ca(2+) release activities in bovine adrenal cortex microsomes by Poirier, S N, Poitras, M, Laflamme, K, Guillemette, G

“…Within all endocrine cells, the inositol 1,4,5-trisphosphate (InsP(3)) receptor plays an important role in regulation of the intracellular Ca(2+)…”
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Thiol-Reactive Agents Biphasically Regulate Inositol 1,4,5-Trisphosphate Binding and Ca2+ Release Activities in Bovine Adrenal Cortex Microsomes1 by Poirier, Stéphane N, Poitras, Marc, Laflamme, Karina, Guillemette, Gaétan

“…Within all endocrine cells, the inositol 1,4,5-trisphosphate (InsP3) receptor plays an important role in regulation of the intracellular Ca2+ concentration. In…”
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Human blood vessels created with tissue engineering by Stoclet, Jean-Claude, Laflamme, Karina, Auger, François A, Germain, Lucie

“…Progress in tissue engineering now allows the recreation of functional blood vessels from cultured human vascular cells. When reconstructed under specific…”
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Thiol-Reactive Agents Biphasically Regulate Inositol 1,4,5-Trisphosphate Binding and Ca2+ Release Activities in Bovine Adrenal Cortex Microsomes by Poirier, Stéphane N., Poitras, Marc, Laflamme, Karina, Guillemette, Gaétan

“…Within all endocrine cells, the inositol 1,4,5-trisphosphate (InsP3) receptor plays an important role in regulation of the intracellular Ca2+ concentration. In…”
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Recent optimization of a tissue engineered blood vessel: the LOEX experience by Auger, François A, Laflamme, Karina, Grenier, Guillaume, Rémy-Zolghadri, Murielle, Germain, Lucie

“…Creating a blood vessel by tissue engineering is one of the most demanding goals in tissue engineering. Our laboratory developed, using the self-assembly…”
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Localisation cellulaire des différents récepteurs à l'inositol 1,4,5-trisphosphate by Laflamme, Karina

“…L'inositol 1,4,5-trisphosphate (InsP3) est un second messager produit de l'hydrolyse du phosphatidylinositol 4,5-bisphosphate par la phospholipase C en réponse…”
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Different populations of inositol 1,4,5-trisphosphate receptors expressed in the bovine adrenal cortex by Poitras, M, Poirier, S N, Laflamme, K, Simoneau, M, Escher, E, Guillemette, G

“…The inositol 1,4,5-trisphosphate (InsP3) receptor forms a tetrameric channel responsible for the release of Ca2+ from intracellular stores. In the present…”
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Tissue-engineered human vascular media produced in vitro by the self-assembly approach present functional properties similar to those of their native blood vessels by Laflamme, Karina, Roberge, Charles J, Pouliot, Stéphanie, D'Orléans-Juste, Pédro, Auger, François A, Germain, Lucie

“…We have developed a tissue-engineering approach for the production of a completely biological blood vessel from cultured human cells. In the present study, we…”
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