Search Results - "Laffleur, B"

Immunoglobulin genes undergo legitimate repair in human B cells not only after cis- but also frequent trans-class switch recombination by Laffleur, B, Bardet, S M, Garot, A, Brousse, M, Baylet, A, Cogné, M

“…Immunoglobulin (Ig) genes specifically recruit activation-induced deaminase (AID) for ‘on-target’ DNA deamination, initiating either variable (V) region…”
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Noncoding RNA transcription alters chromosomal topology to promote isotype-specific class switch recombination by Rothschild, Gerson, Zhang, Wanwei, Lim, Junghyun, Giri, Pankaj Kumar, Laffleur, Brice, Chen, Yiyun, Fang, Mingyan, Chen, Yuling, Nair, Lekha, Liu, Zhi-Ping, Deng, Haiteng, Hammarström, Lennart, Wang, Jiguang, Basu, Uttiya

“…B cells undergo two types of genomic alterations to increase antibody diversity: introduction of point mutations into immunoglobulin heavy- and light-chain (…”
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Specific impairment of proximal tubular cell proliferation by a monoclonal   light chain responsible for Fanconi syndrome by El Hamel, C., Aldigier, J.-C., Oblet, C., Laffleur, B., Bridoux, F., Cogne, M.

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Anti-CD20 IgA can protect mice against lymphoma development: evaluation of the direct impact of IgA and cytotoxic effector recruitment on CD20 target cells by PASCAL, Virginie, LAFFLEUR, Brice, COGNE, Michel, DEBIN, Arnaud, CUVILLIER, Armelle, EGMOND, Marjolein Van, DROCOURT, Daniel, IMBERTIE, Laurent, PANGAULT, Céline, TARTE, Karin, TIRABY, Gerard

“…While most antibody-based therapies use IgG because of their well-known biological properties, some functional limitations of these antibodies call for the…”
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Du self-control lymphocytaire B aux abords thérapeutiques, quelles voies « B-intrinsèques » pour tempérer les réponses et la mémoire IgE ? by Cogné, M., Dalloul, Z., Dézé, O., Le Goff, M., Thomas, S., Cahen, M., Ueda, N., Laffleur, B.

“…Persisting adaptive humoral immunity relies on two key cell types: memory B lymphocytes and long-lived plasma cells. Independently from the specific Ig class…”
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