Search Results - "Laffaire, J"

IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas by HOUILLIER, C, WANG, X, HOANG-XUAN, K, SANSON, M, DELATTRE, J.-Y, KALOSHI, G, MOKHTARI, K, GUILLEVIN, R, LAFFAIRE, J, PARIS, S, BOISSELIER, B, IDBAIH, A, LAIGLE-DONADEY, F

“…Recent studies have shown that IDH1 and IDH2 mutations occur frequently in gliomas, including low-grade gliomas. However, their impact on the prognosis and…”
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All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2 by LABUSSIERE, M, IDBAIH, A, DUCRAY, F, EL HALLANI, S, MOKHTARI, K, HOANG-XUAN, K, DELATTRE, J.-Y, SANSON, M, WANG, X.-W, MARIE, Y, BOISSELIER, B, FALET, C, PARIS, S, LAFFAIRE, J, CARPENTIER, C, CRINIERE, E

“…Recently, the gene encoding the human cytosolic NADPH-dependent isocitrate dehydrogenase (IDH1) was reported frequently mutated in gliomas. Rare mutations were…”
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Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndrome by Altafaj, X, Ortiz-Abalia, J, Fernández, M, Potier, M.C, Laffaire, J, Andreu, N, Dierssen, M, González-García, C, Ceña, V, Martí, E, Fillat, C

“…Abstract Transgenic mice overexpressing Dyrk1A (TgDyrk1A), a Down syndrome (DS) candidate gene, exhibit motor and cognitive alterations similar to those…”
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Comparative analysis of two 14-3-3 homologues and their expression pattern in the root-knot nematode Meloidogyne incognita by Jaubert, S., Laffaire, J.-B., Ledger, T.N., Escoubas, P., Amri, E.-Z., Abad, P., Rosso, M.N.

“…14-3-3 proteins are highly conserved ubiquitous proteins found in all eukaryotic organisms. They are involved in various cellular processes including signal…”
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Transcriptional disruptions in Down syndrome: a case study in the Ts1Cje mouse cerebellum during post‐natal development by Potier, M.‐C., Rivals, I., Mercier, G., Ettwiller, L., Moldrich, R. X., Laffaire, J., Personnaz, L., Rossier, J., Dauphinot, L.

“…To understand the aetiology and the phenotypic severity of Down syndrome, we searched for transcriptional signatures in a substructure of the brain…”
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Transmembrane protein 50b ( C21orf4 ), a candidate for Down syndrome neurophenotypes, encodes an intracellular membrane protein expressed in the rodent brain by Moldrich, R.X, Lainé, J, Visel, A, Beart, P.M, Laffaire, J, Rossier, J, Potier, M.-C

“…Abstract Transmembrane protein 50b, Tmem50b , previously referred to as C21orf4 , encodes a predicted transmembrane protein and is one of few genes…”
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Ectopic activation of germline and placental genes identifies aggressive metastasis-prone lung cancers by Rousseaux, Sophie, Debernardi, Alexandra, Jacquiau, Baptiste, Vitte, Anne-Laure, Vesin, Aurélien, Nagy-Mignotte, Hélène, Moro-Sibilot, Denis, Brichon, Pierre-Yves, Lantuejoul, Sylvie, Hainaut, Pierre, Laffaire, Julien, de Reyniès, Aurélien, Beer, David G, Timsit, Jean-François, Brambilla, Christian, Brambilla, Elisabeth, Khochbin, Saadi

“…Activation of normally silent tissue-specific genes and the resulting cell "identity crisis" are the unexplored consequences of malignant epigenetic…”
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Lung squamous cell carcinomas with basaloid histology represent a specific molecular entity by Brambilla, Christian, Laffaire, Julien, Lantuejoul, Sylvie, Moro-Sibilot, Denis, Mignotte, Hélène, Arbib, François, Toffart, Anne-Claire, Petel, Fabien, Hainaut, Pierre, Rousseaux, Sophie, Khochbin, Saadi, de Reyniès, Aurélien, Brambilla, Elisabeth

“…The basaloid carcinoma (pure) and the (mixed) basaloid variant of lung squamous cell carcinoma (SCC) have a dismal prognosis but their underlying specific…”
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Methylation profiling identifies 2 groups of gliomas according to their tumorigenesis by Laffaire, Julien, Everhard, Sibille, Idbaih, Ahmed, Crinière, Emmanuelle, Marie, Yannick, de Reyniès, Aurelien, Schiappa, Renaud, Mokhtari, Karima, Hoang-Xuan, Khê, Sanson, Marc, Delattre, Jean-Yves, Thillet, Joëlle, Ducray, François

“…Extensive genomic and gene expression studies have been performed in gliomas, but the epigenetic alterations that characterize different subtypes of gliomas…”
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Predictive impact of IDH1 or IDH2 mutations on outcome and response to temozolomide in low-grade gliomas by Houillier, C., Wang, X., Kaloshi, G., Mokhtari, K., Laffaire, J., Boisselier, B., Idbaih, A., Hoang-Xuan, K., Sanson, M., Delattre, J.

“…Abstract only…”
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Chromosome 9p and 10q losses predict unfavorable outcome in low-grade gliomas by Houillier, Caroline, Mokhtari, Karima, Carpentier, Catherine, Crinière, Emmanuelle, Marie, Yannick, Rousseau, Audrey, Kaloshi, Gentian, Dehais, Caroline, Laffaire, Julien, Laigle-Donadey, Florence, Hoang-Xuan, Khê, Sanson, Marc, Delattre, Jean-Yves

“…The loss of chromosomes 1p-19q is the only prognostic molecular alteration identified in low-grade gliomas (LGGs) to date. Search for loss of heterozygosity…”
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SPECIAL ISSUE: Transcriptional disruptions in Down syndrome: a case study in the Ts1Cje mouse cerebellum during post-natal development by M.-C. Potier, Rivals, I, Mercier, G, Ettwiller, L, Moldrich, R X, Laffaire, J, Personnaz, L, Rossier, J, Dauphinot, L

“…To understand the aetiology and the phenotypic severity of Down syndrome, we searched for transcriptional signatures in a substructure of the brain…”
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A polygalacturonase of animal origin isolated from the root-knot nematode Meloidogyne incognita by Jaubert, Stéphanie, Laffaire, Jean-Baptiste, Abad, Pierre, Rosso, Marie-Noëlle

“…The first animal polygalacturonase (PG, EC 2.1.15) encoding cDNA, Mi-pg-1, was cloned from the plant parasitic nematode Meloidogyne incognita. The enzymatic…”
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Direct identification of stylet secreted proteins from root-knot nematodes by a proteomic approach by Jaubert, Stéphanie, Laffaire, Jean Baptiste, Piotte, Christine, Abad, Pierre, Rosso, Marie-Noëlle, Ledger, Terence Neil

“…The stylet secretions produced by plant parasitic root-knot nematodes are thought to be pathogenicity factors involved in the invasion of the root tissue and…”
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