Search Results - "Lafeber, F."
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Knee joint distraction compared with high tibial osteotomy: a randomized controlled trial
Published in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA (01-03-2017)“…Purpose Both, knee joint distraction as a relatively new approach and valgus-producing opening-wedge high tibial osteotomy (HTO), are knee-preserving…”
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Journal Article -
2
Serum adipokines in osteoarthritis; comparison with controls and relationship with local parameters of synovial inflammation and cartilage damage
Published in Osteoarthritis and cartilage (01-08-2012)“…Summary Objective Adipose tissue is an endocrine tissue releasing adipokines suggested to be involved in the pathogenesis of osteoarthritis (OA). Nevertheless,…”
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3
Subchondral bone changes after joint distraction treatment for end stage knee osteoarthritis
Published in Osteoarthritis and cartilage (01-07-2022)“…Increased subchondral cortical bone plate thickness and trabecular bone density are characteristic of knee osteoarthritis (OA). Knee joint distraction (KJD) is…”
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Journal Article -
4
Sustained clinical and structural benefit after joint distraction in the treatment of severe knee osteoarthritis
Published in Osteoarthritis and cartilage (01-11-2013)“…Summary Background Treatment of severe osteoarthritis (OA) in relatively young patients is challenging. Although successful, total knee prosthesis has a…”
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5
The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the dog
Published in Osteoarthritis and cartilage (01-10-2010)“…Summary The dog is a common model for study of osteoarthritis (OA). Subjective histologic scoring systems have often served as the reference standard for…”
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Journal Article Conference Proceeding -
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Alarmins S100A8/S100A9 aggravate osteophyte formation in experimental osteoarthritis and predict osteophyte progression in early human symptomatic osteoarthritis
Published in Annals of the rheumatic diseases (01-01-2016)“…Alarmins S100A8 and S100A9 are major products of activated macrophages regulating cartilage damage and synovial activation during murine and human…”
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7
Pathogenesis of haemophilic arthropathy
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-07-2006)“…The pathogenetic mechanism of haemophilic arthropathy is multifactorial and includes degenerative cartilage‐mediated and inflammatory synovium‐mediated…”
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Journal Article -
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Personalised treatment using serum drug levels of adalimumab in patients with rheumatoid arthritis: an evaluation of costs and effects
Published in Annals of the rheumatic diseases (01-02-2015)“…To evaluate the cost-effectiveness of personalised treatment for rheumatoid arthritis (RA) using clinical response and serum adalimumab levels. A personalised…”
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Journal Article -
9
Initial tissue repair predicts long-term clinical success of knee joint distraction as treatment for knee osteoarthritis
Published in Osteoarthritis and cartilage (01-12-2018)“…Knee joint distraction (KJD), a joint-preserving surgery for severe osteoarthritis (OA), provides clinical and structural improvement and postpones the need…”
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Journal Article -
10
Knee Joint Distraction Compared to Total Knee Arthroplasty for Treatment of End Stage Osteoarthritis: Simulating Long-Term Outcomes and Cost-Effectiveness
Published in PloS one (12-05-2016)“…In end-stage knee osteoarthritis the treatment of choice is total knee arthroplasty (TKA). An alternative treatment is knee joint distraction (KJD), suggested…”
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Journal Article -
11
Osteoarthritis year 2013 in review: biomarkers; reflecting before moving forward, one step at a time
Published in Osteoarthritis and cartilage (01-10-2013)“…Summary In 2010, in Osteoarthritis and Cartilage, we published a comprehensive systematic review applying the consensus BIPED criteria (Burden of Disease,…”
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Journal Article -
12
Canine IL4-10 fusion protein provides disease modifying activity in a canine model of OA; an exploratory study
Published in PloS one (11-07-2019)“…An ideal disease modifying osteoarthritis drug (DMOAD) has chondroprotective, anti-inflammatory, and analgesic effects. This study describes the production and…”
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Journal Article -
13
The association of the lipid profile with knee and hand osteoarthritis severity: the IMI-APPROACH cohort
Published in Osteoarthritis and cartilage (01-08-2022)“…To investigate the association of the lipidomic profile with osteoarthritis (OA) severity, considering the outcomes radiographic knee and hand OA, pain and…”
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Journal Article -
14
Local and systemic inflammatory lipid profiling in a rat model of osteoarthritis with metabolic dysregulation
Published in PloS one (23-04-2018)“…Bioactive oxidised lipids (oxylipins) are important signalling mediators, capable of modulating the inflammatory state of the joint and anticipated to be of…”
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Journal Article -
15
Test–retest precision and longitudinal cartilage thickness loss in the IMI-APPROACH cohort
Published in Osteoarthritis and cartilage (01-02-2023)“…To investigate the test–retest precision and to report the longitudinal change in cartilage thickness, the percentage of knees with progression and the…”
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Journal Article -
16
Serum and urinary biochemical markers for knee and hip-osteoarthritis: a systematic review applying the consensus BIPED criteria
Published in Osteoarthritis and cartilage (01-05-2010)“…Summary Context Molecules that are released into biological fluids during matrix metabolism of articular cartilage, subchondral bone, and synovial tissue could…”
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Journal Article -
17
Differential effects of bleeds on the development of arthropathy – basic and applied issues
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-07-2017)“…Haemophilia is characterized by a spontaneous bleeding tendency, affecting mainly the synovial joints. Recurrent joint bleeds induce a cascade of inflammatory…”
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Journal Article -
18
IL4‐10 fusion protein: a novel immunoregulatory drug combining activities of interleukin 4 and interleukin 10
Published in Clinical and experimental immunology (01-01-2019)“…Summary The objective of this study was to test the capacity of a newly developed fusion protein of interleukin 4 (IL‐4) and IL‐10 [IL4‐10 fusion protein (FP)]…”
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Journal Article -
19
Knee joint distraction compared with total knee arthroplasty: a randomised controlled trial
Published in The bone & joint journal (01-01-2017)“…Knee joint distraction (KJD) is a relatively new, knee-joint preserving procedure with the goal of delaying total knee arthroplasty (TKA) in young and…”
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Journal Article -
20
A Personalized Approach to Biological Therapy Using Prediction of Clinical Response Based on MRP8/14 Serum Complex Levels in Rheumatoid Arthritis Patients
Published in PloS one (30-03-2016)“…Measurement of MRP8/14 serum levels has shown potential in predicting clinical response to different biological agents in rheumatoid arthritis (RA). We aimed…”
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