Search Results - "Laenen, Isabelle"
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Prominent Axonopathy in the Brain and Spinal Cord of Transgenic Mice Overexpressing Four-Repeat Human tau Protein
Published in The American journal of pathology (01-12-1999)“…Mutations in the human tau gene cause frontotemporal dementia and parkinsonism linked to chromosome 17. Some mutations, including mutations in intron 10,…”
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Prominent Cerebral Amyloid Angiopathy in Transgenic Mice Overexpressing the London Mutant of Human APP in Neurons
Published in The American journal of pathology (01-10-2000)“…Deposition of amyloid β-peptide (Aβ) in cerebral vessel walls (cerebral amyloid angiopathy, CAA) is very frequent in Alzheimer’s disease and occurs also as a…”
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Glycogen Synthase Kinase-3β Phosphorylates Protein Tau and Rescues the Axonopathy in the Central Nervous System of Human Four-repeat Tau Transgenic Mice
Published in The Journal of biological chemistry (29-12-2000)“…Protein tau filaments in brain of patients suffering from Alzheimer's disease, frontotemporal dementia, and other tauopathies consist of protein tau that is…”
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4
Aging Increased Amyloid Peptide and Caused Amyloid Plaques in Brain of Old APP/V717I Transgenic Mice by a Different Mechanism than Mutant Presenilin1
Published in The Journal of neuroscience (01-09-2000)“…Aging of transgenic mice that overexpress the London mutant of amyloid precursor protein (APP/V717I) (Moechars et al., 1999a) was now demonstrated not to…”
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Aggressive behaviour in transgenic mice expressing APP is alleviated by serotonergic drugs
Published in Neuroreport (16-11-1998)“…TRANSGENIC mouse strains were generated that over-express human APP or clinical mutants of APP. All transgenic mouse strains that over-express APP displayed…”
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Glycogen Synthase Kinase-3β Phosphorylates Protein Tau and Rescues the Axonopathy in the Central Nervous System of Human Four-repeat Tau Transgenic Mice
Published in The Journal of biological chemistry (29-12-2000)“…Protein tau filaments in brain of patients suffering from Alzheimer's disease, frontotemporal dementia, and other tauopathies consist of protein tau that is…”
Get full text
Journal Article