Search Results - "Ladwa, Sweta"
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Li-Fraumeni Exploration Consortium Data Coordinating Center: Building an Interactive Web-Based Resource for Collaborative International Cancer Epidemiology Research for a Rare Condition
Published in Cancer epidemiology, biomarkers & prevention (01-05-2020)“…The success of multisite collaborative research relies on effective data collection, harmonization, and aggregation strategies. Data Coordination Centers (DCC)…”
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Simvastatin Sodium Salt and Fluvastatin Interact with Human Gap Junction Gamma-3 Protein
Published in PloS one (10-02-2016)“…Finding pleiomorphic targets for drugs allows new indications or warnings for treatment to be identified. As test of concept, we applied a new chemical…”
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Mapping DNA Adducts of Mitomycin C and Decarbamoyl Mitomycin C in Cell Lines Using Liquid Chromatography/Electrospray Tandem Mass Spectrometry
Published in Chemical research in toxicology (15-12-2008)“…The antitumor antibiotic and cancer chemotherapeutic agent mitomycin C (MC) alkylates and cross-links DNA, forming six major MC-deoxyguanosine adducts of known…”
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Rapid Identification of a Putative Interaction between β2-Adrenoreceptor Agonists and ATF4 using a Chemical Genomics Approach
Published in ChemMedChem (19-05-2008)“…Chemical genomics. We have uncovered a specific interaction between the β2‐adrenoreceptor agonist salbutamol and the DNA binding region of transcription factor…”
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Building a collaborative cloud platform to accelerate heart, lung, blood, and sleep research
Published in Journal of the American Medical Informatics Association : JAMIA (20-06-2023)“…Abstract Research increasingly relies on interrogating large-scale data resources. The NIH National Heart, Lung, and Blood Institute developed the NHLBI…”
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Synthesis of an Oligodeoxyribonucleotide Adduct of Mitomycin C by the Postoligomerization Method via a Triamino Mitosene
Published in Journal of the American Chemical Society (23-07-2008)“…The cancer chemotherapeutic agent mitomycin C (MC) alkylates and cross-links DNA monofunctionally and bifunctionally in vivo and in vitro, forming six major…”
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Informatics and data quality at collaborative multicenter Breast and Colon Cancer Family Registries
Published in Journal of the American Medical Informatics Association : JAMIA (01-06-2012)“…Quality control and harmonization of data is a vital and challenging undertaking for any successful data coordination center and a responsibility shared…”
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Simvastatin Sodium Salt and Fluvastatin Interact with Human Gap Junction Gamma-3 Protein: e0148266
Published in PloS one (01-02-2016)“…Finding pleiomorphic targets for drugs allows new indications or warnings for treatment to be identified. As test of concept, we applied a new chemical…”
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Rapid Identification of a Putative Interaction between β 2 ‐Adrenoreceptor Agonists and ATF4 using a Chemical Genomics Approach
Published in ChemMedChem (19-05-2008)Get full text
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Rapid identification of a putative interaction between beta2-adrenoreceptor agonists and ATF4 using a chemical genomics approach
Published in ChemMedChem (01-05-2008)Get full text
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Synthesis of 2-aryl-2H-indazoles by base catalysed reaction of 2-nitrobenzyl triphenylphosphonium bromide and aryl isocyanates
Published in Tetrahedron letters (09-12-2000)“…The synthesis of a series of 2-aryl-2H-indazoles is reported. These compounds are obtained in moderate to good yield by reaction of 2-nitrobenzyl…”
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Novel pyridinium linkers for solid phase synthesis
Published 01-01-2004“…This thesis describes the synthesis of novel pyridinium linkers for solid phase synthesis. In the first instance, Merrifield resins were employed to attach a…”
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Dissertation