Search Results - "Ladoux, Benoit"

Cell migration guided by long-lived spatial memory by d’Alessandro, Joseph, Barbier--Chebbah, Alex, Cellerin, Victor, Benichou, Olivier, Mège, René Marc, Voituriez, Raphaël, Ladoux, Benoît

“…Living cells actively migrate in their environment to perform key biological functions—from unicellular organisms looking for food to single cells such as…”
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Cell response to substrate rigidity is regulated by active and passive cytoskeletal stress by Doss, Bryant L., Pan, Meng, Gupta, Mukund, Grenci, Gianluca, Mège, René-Marc, Lim, Chwee Teck, Sheetz, Michael P., Voituriez, Raphaël, Ladoux, Benoît

“…Morphogenesis, tumor formation, and wound healing are regulated by tissue rigidity. Focal adhesion behavior is locally regulated by stiffness; however, how…”
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Sustained Oscillations of Epithelial Cell Sheets by Peyret, Grégoire, Mueller, Romain, d’Alessandro, Joseph, Begnaud, Simon, Marcq, Philippe, Mège, René-Marc, Yeomans, Julia M., Doostmohammadi, Amin, Ladoux, Benoît

“…Morphological changes during development, tissue repair, and disease largely rely on coordinated cell movements and are controlled by the tissue environment…”
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Active nematics across scales from cytoskeleton organization to tissue morphogenesis by Balasubramaniam, Lakshmi, Mège, René-Marc, Ladoux, Benoît

“…Biological tissues are composed of various cell types working cooperatively to perform their respective function within organs and the whole body. During…”
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Mechanics of epithelial tissues during gap closure by Begnaud, Simon, Chen, Tianchi, Delacour, Delphine, Mège, René-Marc, Ladoux, Benoît

“…The closure of gaps is crucial to maintaining epithelium integrity during developmental and repair processes such as dorsal closure and wound healing…”
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Front–Rear Polarization by Mechanical Cues: From Single Cells to Tissues by Ladoux, Benoit, Mège, René-Marc, Trepat, Xavier

“…Directed cell migration is a complex process that involves front–rear polarization, characterized by cell adhesion and cytoskeleton-based protrusion,…”
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Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness by Trichet, Léa, Le Digabel, Jimmy, Hawkins, Rhoda J., Vedula, Sri Ram Krishna, Gupta, Mukund, Ribrault, Claire, Hersen, Pascal, Voituriez, Raphaël, Ladoux, Benoît

“…Cell migration plays a major role in many fundamental biological processes, such as morphogenesis, tumor metastasis, and wound healing. As they anchor and pull…”
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Topological defects in epithelia govern cell death and extrusion by Saw, Thuan Beng, Doostmohammadi, Amin, Nier, Vincent, Kocgozlu, Leyla, Thampi, Sumesh, Toyama, Yusuke, Marcq, Philippe, Lim, Chwee Teck, Yeomans, Julia M., Ladoux, Benoit

“…By modelling epithelial cells as active nematic liquid crystals, stresses induced at the sites of topological defects are found to be the primary drivers of…”
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Desmosomal Junctions Govern Tissue Integrity and Actomyosin Contractility in Apoptotic Cell Extrusion by Thomas, Minnah, Ladoux, Benoit, Toyama, Yusuke

“…During apoptosis, or programmed cell death, a dead cell could be expelled from the tissue by coordinated processes between the dying cell and its neighbors…”
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Biological Tissues as Active Nematic Liquid Crystals by Saw, Thuan Beng, Xi, Wang, Ladoux, Benoit, Lim, Chwee Teck

“…Live tissues can self‐organize and be described as active materials composed of cells that generate active stresses through continuous injection of energy. In…”
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Adaptive rheology and ordering of cell cytoskeleton govern matrix rigidity sensing by Gupta, Mukund, Sarangi, Bibhu Ranjan, Deschamps, Joran, Nematbakhsh, Yasaman, Callan-Jones, Andrew, Margadant, Felix, Mège, René-Marc, Lim, Chwee Teck, Voituriez, Raphaël, Ladoux, Benoît

“…Matrix rigidity sensing regulates a large variety of cellular processes and has important implications for tissue development and disease. However, how cells…”
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Rigidity-driven growth and migration of epithelial cells on microstructured anisotropic substrates by Saez, Alexandre, Ghibaudo, Marion, Buguin, Axel, Silberzan, Pascal, Ladoux, Benoît

“…The physical properties of the cellular environment are involved in regulating the formation and maintenance of tissues. In particular, substrate rigidity…”
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Coordination between Intra- and Extracellular Forces Regulates Focal Adhesion Dynamics by Sarangi, Bibhu Ranjan, Gupta, Mukund, Doss, Bryant L, Tissot, Nicolas, Lam, France, Mège, René-Marc, Borghi, Nicolas, Ladoux, Benoît

“…Focal adhesions (FAs) are important mediators of cell–substrate interactions. One of their key functions is the transmission of forces between the…”
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Myosin II isoforms play distinct roles in adherens junction biogenesis by Heuzé, Mélina L, Sankara Narayana, Gautham Hari Narayana, D'Alessandro, Joseph, Cellerin, Victor, Dang, Tien, Williams, David S, Van Hest, Jan Cm, Marcq, Philippe, Mège, René-Marc, Ladoux, Benoit

“…Adherens junction (AJ) assembly under force is essential for many biological processes like epithelial monolayer bending, collective cell migration, cell…”
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Mechanical plasticity in collective cell migration by Jain, Shreyansh, Ladoux, Benoit, Mège, René-Marc

“…Collective cell migration is crucial to maintain epithelium integrity during developmental and repair processes. It requires a tight regulation of mechanical…”
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Emergent patterns of collective cell migration under tubular confinement by Xi, Wang, Sonam, Surabhi, Beng Saw, Thuan, Ladoux, Benoit, Teck Lim, Chwee

“…Collective epithelial behaviors are essential for the development of lumens in organs. However, conventional assays of planar systems fail to replicate cell…”
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Cell crawling mediates collective cell migration to close undamaged epithelial gaps by Anon, Ester, Serra-Picamal, Xavier, Hersen, Pascal, Gauthier, Nils C, Sheetz, Michael P, Trepat, Xavier, Ladoux, Benoît

“…Fundamental biological processes such as morphogenesis and wound healing involve the closure of epithelial gaps. Epithelial gap closure is commonly attributed…”
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Active superelasticity in three-dimensional epithelia of controlled shape by Latorre, Ernest, Kale, Sohan, Casares, Laura, Gómez-González, Manuel, Uroz, Marina, Valon, Léo, Nair, Roshna V., Garreta, Elena, Montserrat, Nuria, del Campo, Aránzazu, Ladoux, Benoit, Arroyo, Marino, Trepat, Xavier

“…Fundamental biological processes are carried out by curved epithelial sheets that enclose a pressurized lumen. How these sheets develop and withstand…”
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Mechanical forces in cell monolayers by Chen, Tianchi, Saw, Thuan Beng, Mège, René-Marc, Ladoux, Benoit

“…In various physiological processes, the cell collective is organized in a monolayer, such as seen in a simple epithelium. The advances in the understanding of…”
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Is the Mechanical Activity of Epithelial Cells Controlled by Deformations or Forces? by Saez, Alexandre, Buguin, Axel, Silberzan, Pascal, Ladoux, Benoît

“…The traction forces developed by cells depend strongly on the substrate rigidity. In this letter, we characterize quantitatively this effect on MDCK epithelial…”
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