Search Results - "Ladin, Daniel A"

Preclinical and Clinical Assessment of Cannabinoids as Anti-Cancer Agents by Ladin, Daniel A, Soliman, Eman, Griffin, LaToya, Van Dross, Rukiyah

“…Cancer is the second leading cause of death in the United States with 1.7 million new cases estimated to be diagnosed in 2016. This disease remains a…”
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Apoptosis mechanisms induced by 15d-PMJ2 in HCT116 colon cancer cells: insights into CHOP10/TRB3/Akt signaling by Albassam, Hussam, Ladin, Daniel A., Elhassanny, Ahmed, Burns, Colin, Van Dross-Anderson, Rukiyah

“…Agents that stimulate the endoplasmic reticulum (ER) stress pathway are being exploited pharmacologically to induce cancer cell death. Cytotoxic ER stress is…”
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Corrigendum: Preclinical and Clinical Assessment of Cannabinoids as Anti-Cancer Agents by Ladin, Daniel A., Soliman, Eman, Griffin, LaToya, Van Dross, Rukiyah

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Glycopyrrolate Premedication and Procedure-Related Events in Pediatric Upper Endoscopy by Tumin, Dmitry, Ladin, Daniel A, Ledoux, Matthew

“…Glycopyrrolate premedication is used for pediatric upper endoscopy procedures, with limited clinical evidence for efficacy. We investigated whether…”
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Cardiac Complications of Radiation Therapy by Zaghlol, Raja, Pedersen, Lauren, Qamer, Syed, Yoo, Sang Gune K., Ladin, Daniel A., Parvathaneni, Adeesh, Bergom, Carmen, Mitchell, Joshua D.

“…Radiation therapy is a critical component in managing many malignancies by improving local control and survival. The benefits of radiation may come at the…”
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Calcium signaling induced by 15-deoxy-prostamide-J2 promotes cell death by activating PERK, IP3R, and the mitochondrial permeability transition pore by Ladin, Daniel A, Nelson, Margaret M, Cota, Estefani, Colonna, Catherine, Burns, Colin, Robidoux, Jacques, Fisher-Wellman, Kelsey H, Van Dross-Anderson, Rukiyah

“…Melanoma is the deadliest form of skin cancer in the US. Although immunotherapeutic checkpoint inhibitors and small-molecule kinase inhibitors have…”
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Prostaglandin D 2 -ethanolamide induces skin cancer apoptosis by suppressing the activity of cellular antioxidants by Elhassanny, Ahmed E M, Ladin, Daniel A, Soliman, Eman, Albassam, Hussam, Morris, Andrew, Kobet, Robert, Thayne, Kathleen, Burns, Colin, Danell, Allison S, Van Dross, Rukiyah

“…The combined incidence of melanoma and non-melanoma skin cancer (NMSC) is greater than the incidence of all other malignancies in the US. Previously, we…”
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p53 and apoptosis alterations in keloids and keloid fibroblasts by Ladin, Daniel A., Hou, Zizheng, Patel, Dipa, McPhail, Monica, Olson, Jennifer C., Saed, Ghassan M., Fivenson, David P.

“…Keloids are the result of a dysregulated wound‐healing process and are characterized by formation of excess scar tissue that proliferates beyond the boundaries…”
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Prostaglandin D2-ethanolamide induces skin cancer apoptosis by suppressing the activity of cellular antioxidants by Elhassanny, Ahmed E.M., Ladin, Daniel A., Soliman, Eman, Albassam, Hussam, Morris, Andrew, Kobet, Robert, Thayne, Kathleen, Burns, Colin, Danell, Allison S., Van Dross, Rukiyah

“…•PGD2-EA causes apoptotic cell death in melanoma and non-melanoma skin cancer cells.•PGD2-EA is metabolized to J-series prostaglandin-ethanolamides in skin…”
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Synthesis and Evaluation of the Novel Prostamide, 15-Deoxy, Δ12,14-Prostamide J2, as a Selective Antitumor Therapeutic by Ladin, Daniel A., Soliman, Eman, Escobedo, Rene, Fitzgerald, Timothy L., Yang, Li V., Burns, Colin, Van Dross, Rukiyah

“…15-deoxy, Δ12,14-prostaglandin J2-ethanolamide, also known as 15-deoxy, Δ12,14-prostamide J2 (15d-PMJ2) is a novel product of the metabolism of arachidonoyl…”
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Abstract 3873: CHOP10/TRB3/Akt signaling regulates ER stress apoptosis in colon cancer cells treated with prostamide-J by Albassam, Hussam, Ladin, Daniel A., Dross, Rukiyah Van

“…The endoplasmic reticulum (ER) is a cellular organelle that is primarily responsible for oxidative protein folding. When the protein folding load in cells…”
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α1-Antitrypsin Is Degraded and Non-Functional in Chronic Wounds But Intact and Functional in Acute Wounds: The Inhibitor Protects Fibronectin from Degradation by Chronic Wound Fluid Enzymes by Rao, C.N., Ladin, Daniel A., Chilukuri, Krishna, Woodley, David T., Liu, Yiu Ying, Hou, Zi Zheng

“…Fluid obtained from chronic and acute wounds were examined for the presence of fibronectin, α1-antitrypsin, and proteinases capable of degrading both proteins…”
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Abstract 2097: A novel J-series prostamide induces ER stress-mediated apoptosis and upregulates ER oxidoreductase 1 alpha (ERO1α) in human colon cancer cells by Albassam, Hussam M., Ladin, Daniel A., Dross, Rukiyah Van

“…Colon cancer is the third most common cancer and the third leading cause of cancer-related death in the United States. The endoplasmic reticulum (ER) is a…”
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Abstract 3217: Novel prostamide, 15-deoxy-delta12,14 prostamide J2, displays activity against melanoma in vitro and in vivo : potential role of endoplasmic reticulum stress by Ladin, Daniel A., Yang, Li V., Fitzgerald, Timothy L., Dross, Rukiyah Van

“…Melanoma is the most aggressive and deadly form of cutaneous neoplasm in the United States, representing a major clinical challenge. Our lab previously…”
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Synthesis and Evaluation of the Novel Prostamide, 15-Deoxy, Delta 12,14-Prostamide J2, as a Selective Antitumor Therapeutic by Ladin, Daniel A, Soliman, Eman, Escobedo, Rene, Fitzgerald, Timothy L, Yang, Li V, Burns, Colin, Van Dross, Rukiyah

“…15-deoxy, Delta 12,14-prostaglandin J2-ethanolamide, also known as 15-deoxy, Delta 12,14-prostamide J2 (15d-PMJ2) is a novel product of the metabolism of…”
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Synthesis and Molecular Evaluation of 15-Deoxy-Δ 12,14-Prostamide J2 as a Novel Anti-Skin Cancer Agent by Ladin, Daniel A

“…Skin cancers including non-melanoma skin cancer (NMSC) and melanoma are the most common form of cancer in the United States and thus represent a substantial…”
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Synthesis and Evaluation of the Novel Prostamide, 15-Deoxy, Δ 12,14 -Prostamide J 2 , as a Selective Antitumor Therapeutic by Ladin, Daniel A, Soliman, Eman, Escobedo, Rene, Fitzgerald, Timothy L, Yang, Li V, Burns, Colin, Van Dross, Rukiyah

“…15-deoxy, Δ -prostaglandin J -ethanolamide, also known as 15-deoxy, Δ -prostamide J (15d-PMJ ) is a novel product of the metabolism of arachidonoyl…”
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Understanding dressings by Ladin, D A

“…Currently our understanding of chronic wound pathophysiology is deficient in knowing what specifically is lacking during arrested wound healing. Autologous or…”
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Effects of oxygen on wound responses to growth factors: Kaposi's FGF, but not basic FGF stimulates repair in ischemic wounds by Wu, L, Pierce, G F, Ladin, D A, Zhao, L L, Rogers, D, Mustoe, T A

“…Kaposi's fibroblast growth factor (K-FGF, FGF-4) is a newer member of FGF family with uncharacterized wound healing properties. Basic fibroblast growth factor…”
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Acute repair of a full-thickness right ventricular defect with a composite myofascial pedicle flap by Ladin, D A, Smith, D P, Izenberg, P H, Deschner, W P

“…A full-thickness defect of the right ventricle presented acutely after mediastinitis and sternal dehiscence. This developed 29 days after bilateral internal…”
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