Search Results - "Ladd, David L"

Polymeric Gadolinium Chelate Magnetic Resonance Imaging Contrast Agents:  Design, Synthesis, and Properties by Ladd, David L, Hollister, Robert, Peng, Xin, Wei, Donna, Wu, Gang, Delecki, Daniel, Snow, Robert A, Toner, John L, Kellar, Kenneth, Eck, Jennifer, Desai, Vinay C, Raymond, Gemma, Kinter, Lewis B, Desser, Terry S, Rubin, Daniel L

“…We have synthesized and evaluated five series of polymeric gadolinium chelates which are of interest as potential MRI blood pool contrast agents. The polymers…”
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Synthesis and dopaminergic binding of 2-aryldopamine analogs: phenethylamines, 3-benzazepines, and 9-(aminomethyl)fluorenes by Ladd, David L, Weinstock, Joseph, Wise, Margaret, Gessner, George W, Sawyer, John L, Flaim, Kathryn E

“…A series of 2-aryldopamine analogues were synthesized and evaluated for their effects on D1 and D2 dopamine receptors. The 2-phenyldopamine and…”
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Synthesis and tubulin binding of 4'-(1-azi-2,2,2-trifluoroethyl)oncodazole, a photolabile analog of oncodazole by Ladd, David L, Harrsch, Peter B, Kruse, Lawrence I

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Separation of potent central and renal dopamine agonist activity in substituted 6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepines by Weinstock, Joseph, Wilson, James W, Ladd, David L, Brush, Charles K, Pfeiffer, Francis R, Kuo, George Y, Holden, Kenneth G, Yim, Nelson C. F, Hahn, Richard A

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Synthesis of optically active dialkylarylsulfonium salts from alkyl aryl sulfoxides by Andersen, Kenneth K, Caret, Robert L, Ladd, David L

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Synthesis, tubulin binding, antineoplastic evaluation, and structure-activity relationship of oncodazole analogs by Kruse, Lawrence I, Ladd, David L, Harrsch, Peter B, McCabe, Francis L, Mong, Shau Ming, Faucette, Leo, Johnson, Randall

“…In an attempt to identify a soluble oncodazole analogue that could be easily formulated, a series of substituted oncodazoles was synthesized and evaluated for…”
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Improved synthesis of fluoroveratroles and fluorophenethylamines via organolithium reagents by Ladd, David L, Weinstock, Joseph

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Synthesis and renal vasodilator activity of some dopamine agonist 1-aryl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diols: halogen and methyl analogs of fenoldopam by Weinstock, Joseph, Ladd, David L, Wilson, James W, Brush, Charles K, Yim, Nelson C. F, Gallagher, Gregory, McCarthy, Mary E, Silvestri, Joanne, Sarau, Henry M

“…Certain 6-halo-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines were found to be potent D-1 dopamine agonists. The 1-(4-hydroxyphenyl) analogues did not have…”
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Steroidal A ring aryl carboxylic acids: a new class of steroid 5.alpha.-reductase inhibitors by Holt, Dennis A, Levy, Mark A, Ladd, David L, Oh, Hye Ja, Erb, Jill M, Heaslip, Julie I, Brandt, Martin, Metcalf, Brian W

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Dynamics of tumor imaging with Gd-DTPA-polyethylene glycol polymers: dependence on molecular weight by Desser, T S, Rubin, D L, Muller, H H, Qing, F, Khodor, S, Zanazzi, G, Young, S W, Ladd, D L, Wellons, J A, Kellar, K E

“…Macromolecular contrast media offer potential advantages over freely diffusible agents in magnetic resonance (MR) imaging outside the central nervous system…”
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Time-of-flight MR angiography with Gd-DTPA hexamethylene diamine co-polymer blood pool contrast agent: Comparison of enhanced MRA and conventional angiography for arterial stenosis induced in rabbits by Bonk, R. Thomas, Schmiedl, Udo P., Yuan, Chun, Nelson, James A., Black, Chris D.V., Ladd, David L.

“…Vascular stenoses were induced in the external iliac arteries of New Zealand white rabbits by a combination of hypercholesterolemic diet and repeat balloon…”
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Synthesis and NMR Characterization of Monomethoxypoly(Ethylene Glycol) Aldehydes from Monomethoxypoly(Ethylene Glycol) Tosylates by Ladd, David L., Henrichs, P. Mark

“…A procedure for the synthesis of monomethoxypoly(ethylene glycol) aldehydes from monomethoxypoly(ethylene glycol) tosylates is described. The tosylates are…”
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Black blood magnetic resonance angiography with Dy-DTPA polymer: effect on arterial intraluminal signal intensity, lumen diameter, and wall thickness by Eubank, W B, Schmiedl, U P, Yuan, C, Black, C D, Kellar, K E, Ladd, D L, Nelson, J A

“…Four rabbits in which atherosclerotic disease was induced by diet and balloon angioplasty underwent conventional angiography and MR angiography (MRA) using a…”
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Steroidal a ring aryl carboxylic acids : a new class of steroid 5α-reductase inhibitors by HOLT, D. A, LEVY, M. A, LADD, D. L, HYE-JA OH, ERB, J. M, HEASLIP, J. I, BRANDT, M, METCALF, B. W

“…A series of 17 beta-carbamoyl-1,3,5(10)-estratriene-3-carboxylic acids has been prepared and evaluated in vitro as inhibitors of human and rat prostatic…”
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Reagents for the preparation of chromophorically labeled polyethylene glycol-protein conjugates by Ladd, D L, Snow, R A

“…We have developed a new class of reagents (2) for the covalent attachment of polyethylene glycol to proteins. These reagents (2) are the…”
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Synthesis of some substituted guanidinopyrimidines and their structural assignment by 13C and 1H NMR by Ladd, David L.

“…A series of substituted 2‐ and 4‐guanidinopyrimidines were prepared by reaction of halopyrimidines with guanidine; alkylamino and amino substituents were…”
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Synthesis of some substituted guanidinopyrimidines and their structural assignment by 13 C and 1 H NMR by Ladd, David L.

“…Abstract A series of substituted 2‐ and 4‐guanidinopyrimidines were prepared by reaction of halopyrimidines with guanidine; alkylamino and amino substituents…”
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Binding constant determination of WIN 22169, a novel polymeric ligand by Chellquist, E M, Searle, R, Ladd, D L, Hollister, R K

“…WIN 22169 is a co-polymer containing approximately 11 repeating units of polyoxyethylene and diethylenetriamine pentaacetic acid (DTPA). WIN 66368, a magnetic…”
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BUSINESS AGGRESSION UNDER THE PATENT SYSTEM by Ladd, David L

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Business Aggression under the Patent System by Ladd, David L.

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