Search Results - "Lacroix, Sonia"
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Intestinal organoids in farm animals
Published in Veterinary research (Paris) (25-02-2021)“…In livestock species, the monolayer of epithelial cells covering the digestive mucosa plays an essential role for nutrition and gut barrier function. However,…”
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Eimeria tenella ROP kinase EtROP1 induces G0/G1 cell cycle arrest and inhibits host cell apoptosis
Published in Cellular microbiology (01-07-2019)“…Coccidia are obligate intracellular protozoan parasites responsible for human and veterinary diseases. Eimeria tenella, the aetiologic agent of caecal…”
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Paneth Cell Defects Induce Microbiota Dysbiosis in Mice and Promote Visceral Hypersensitivity
Published in Gastroenterology (New York, N.Y. 1943) (01-12-2017)“…Separation of newborn rats from their mothers induces visceral hypersensitivity and impaired epithelial secretory cell lineages when they are adults. Little is…”
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Mapping the scientific output of organoids for animal and human modeling infectious diseases: a bibliometric assessment
Published in Veterinary research (Paris) (26-06-2024)“…The escalation of antibiotic resistance, pandemics, and nosocomial infections underscores the importance of research in both animal and human infectious…”
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Cross-Talk Between the Intestinal Epithelium and Salmonella Typhimurium
Published in Frontiers in microbiology (06-06-2022)“…Salmonella enterica serovars are invasive gram-negative bacteria, causing a wide range of diseases from gastroenteritis to typhoid fever, representing a public…”
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Differential Salmonella Typhimurium intracellular replication and host cell responses in caecal and ileal organoids derived from chicken
Published in Veterinary research (Paris) (31-07-2023)“…Chicken infection with Salmonella Typhimurium is an important source of foodborne human diseases. Salmonella colonizes the avian intestinal tract and more…”
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Intestinal organoids to model Salmonella infection and its impact on progenitors
Published in Scientific reports (02-07-2024)“…In order to survive and replicate, Salmonella has evolved mechanisms to gain access to intestinal epithelial cells of the crypt. However, the impact of…”
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Downregulation of the Na/K-ATPase pump by leptospiral glycolipoprotein activates the NLRP3 inflammasome
Published in The Journal of immunology (1950) (15-03-2012)“…Leptospira interrogans is responsible for a zoonotic disease known to induce severe kidney dysfunction and inflammation. In this work, we demonstrate that L…”
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Poly(I:C)-Induced Protection of Neonatal Mice Against Intestinal Cryptosporidium parvum Infection Requires an Additional TLR5 Signal Provided by the Gut Flora
Published in The Journal of infectious diseases (01-02-2014)“…The neonatal intestinal immune system is still undergoing development at birth, leading to a higher susceptibility to mucosal infections. In this study, we…”
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Characterization of intestinal mononuclear phagocyte subsets in young ruminants at homeostasis and during Cryptosporidium parvum infection
Published in Frontiers in immunology (02-05-2024)“…Cryptosporidiosis is a poorly controlled zoonosis caused by an intestinal parasite, , with a high prevalence in livestock (cattle, sheep, and goats). Young…”
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TLR4- and TLR2-Mediated B Cell Responses Control the Clearance of the Bacterial Pathogen, Leptospira interrogans
Published in The Journal of immunology (1950) (15-08-2009)“…Leptospirosis is a widespread zoonosis caused by pathogenic Leptospira interrogans that are transmitted by asymptomatic infected rodents. Leptospiral…”
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Intestinal CD103+ dendritic cells are key players in the innate immune control of Cryptosporidium parvum infection in neonatal mice
Published in PLoS pathogens (01-12-2013)“…Cryptosporidium parvum is a zoonotic protozoan parasite found worldwide, that develops only in the gastrointestinal epithelium and causes profuse diarrhea…”
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Cryptosporidium parvum increases intestinal permeability through interaction with epithelial cells and IL‐1β and TNFα released by inflammatory monocytes
Published in Cellular microbiology (01-12-2016)“…Summary Intestinal epithelial cells form a single layer separating the intestinal lumen containing nutriments and microbiota from the underlying sterile tissue…”
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Leptospira Interrogans induces fibrosis in the mouse kidney through Inos-dependent, TLR- and NLR-independent signaling pathways
Published in PLoS neglected tropical diseases (01-01-2014)“…Leptospira (L.) interrogans are bacteria responsible for a worldwide reemerging zoonosis. Rodents carry L. interrogans asymptomatically in their kidneys and…”
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The caecal microbiota promotes the acute inflammatory response and the loss of the intestinal barrier integrity during severe Eimeria tenella infection
Published in Frontiers in cellular and infection microbiology (23-08-2023)“…Introduction Coccidiosis, a disease caused by intestinal apicomplexan parasites Eimeria , is a threat to poultry production. Eimeria tenella is one of the most…”
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Update on Cryptosporidium spp.: highlights from the Seventh International Giardia and Cryptosporidium Conference
Published in Parasite (Paris) (2020)“…While cryptosporidiosis is recognized as being among the most common causes of human parasitic diarrhea in the world, there is currently limited knowledge on…”
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Exploring the impact of digestive physicochemical parameters of adults and infants on the pathophysiology of Cryptosporidium parvum using the dynamic TIM-1 gastrointestinal model
Published in Gut pathogens (01-10-2024)“…Human cryptosporidiosis is distributed worldwide, and it is recognised as a leading cause of acute diarrhoea and death in infants in low- and middle-income…”
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The Absence of Gut Microbiota Alters the Development of the Apicomplexan Parasite Eimeria tenella
Published in Frontiers in cellular and infection microbiology (04-02-2021)“…Coccidiosis is a widespread intestinal disease of poultry caused by a parasite of the genus is one of the most virulent species that specifically colonizes the…”
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Overexpression of Eimeria tenella Rhoptry Kinase 2 Induces Early Production of Schizonts
Published in Microbiology spectrum (17-08-2023)“…Eimeria tenella is an obligate intracellular parasite responsible for avian coccidiosis. Like other apicomplexan parasites, such as Toxoplasma gondii, cell…”
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Reduced parasite motility and micronemal protein secretion by a p38 MAPK inhibitor leads to a severe impairment of cell invasion by the apicomplexan parasite Eimeria tenella
Published in PloS one (17-02-2015)“…E. tenella infection is associated with a severe intestinal disease leading to high economic losses in poultry industry. Mitogen activated protein kinases…”
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