Search Results - "Lacroix, Benjamin"
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Spatial and Temporal Scaling of Microtubules and Mitotic Spindles
Published in Cells (Basel, Switzerland) (01-01-2022)“…During cell division, the mitotic spindle, a macromolecular structure primarily comprised of microtubules, drives chromosome alignment and partitioning between…”
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2
In Vitro Reconstitution of Dynein Force Exertion in a Bulk Viscous Medium
Published in Current biology (16-11-2020)“…The forces generated by microtubules (MTs) and their associated motors orchestrate essential cellular processes ranging from vesicular trafficking to…”
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3
Tubulin polyglutamylation stimulates spastin-mediated microtubule severing
Published in The Journal of cell biology (14-06-2010)“…Posttranslational glutamylation of tubulin is present on selected subsets of microtubules in cells. Although the modification is expected to contribute to the…”
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4
A Targeted Multienzyme Mechanism for Selective Microtubule Polyglutamylation
Published in Molecular cell (11-05-2007)“…Polyglutamylases are enzymes that form polyglutamate side chains of variable lengths on proteins. Polyglutamylation of tubulin is believed to regulate…”
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5
Structural, enzymatic and spatiotemporal regulation of PP2A-B55 phosphatase in the control of mitosis
Published in Frontiers in cell and developmental biology (29-08-2022)“…Cells require major physical changes to induce a proper repartition of the DNA. Nuclear envelope breakdown, DNA condensation and spindle formation are promoted…”
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6
Synergistic stabilization of microtubules by BUB-1, HCP-1, and CLS-2 controls microtubule pausing and meiotic spindle assembly
Published in eLife (17-02-2023)“…During cell division, chromosome segregation is orchestrated by a microtubule-based spindle. Interaction between spindle microtubules and kinetochores is…”
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Kinetochore components are required for central spindle assembly
Published in Nature cell biology (01-05-2015)“…Using C. elegans zygotes, Dumont and colleagues find that kinetochore proteins, including KNL-1, participate in assembly of central spindle microtubules for…”
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Quantitative analysis of cytokinesis in situ during C. elegans postembryonic development
Published in PloS one (20-10-2014)“…The physical separation of a cell into two daughter cells during cytokinesis requires cell-intrinsic shape changes driven by a contractile ring. However, in…”
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Polyglutamylation Is a Post-translational Modification with a Broad Range of Substrates
Published in The Journal of biological chemistry (15-02-2008)“…Polyglutamylation is a post-translational modification that generates lateral acidic side chains on proteins by sequential addition of glutamate amino acids…”
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10
Kinetic Analysis of Tubulin Assembly in the Presence of the Microtubule-associated Protein TOGp
Published in The Journal of biological chemistry (23-02-2007)“…The microtubule-associated protein TOGp, which belongs to a widely distributed protein family from yeasts to humans, is highly expressed in human tumors and…”
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11
Cytokinesis, ploidy and aneuploidy
Published in The Journal of pathology (01-01-2012)“…Cytokinesis is the last step of cell division that physically separates the daughter cells. As such, it ensures the proper inheritance of both nuclear and…”
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12
Region-based memetic algorithm with archive for multimodal optimisation
Published in Information sciences (01-11-2016)“…In this paper we propose a specially designed memetic algorithm for multimodal optimisation problems. The proposal uses a niching strategy, called region-based…”
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13
Increases in cyclin A/Cdk activity and in PP2A-B55 inhibition by FAM122A are key mitosis-inducing events
Published in The EMBO journal (15-03-2024)“…Entry into mitosis has been classically attributed to the activation of a cyclin B/Cdk1 amplification loop via a partial pool of this kinase becoming active at…”
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14
Increases in cyclin A/Cdk activity and in PP2A-B55 inhibition by FAM122A are key mitosis-inducing events
Published in The EMBO journal (20-02-2024)“…Entry into mitosis has been classically attributed to activation of a cyclin B/Cdk1 amplification loop via a partial pool of this kinase becoming active at the…”
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15
Increases in cyclin A/Cdk activity and in PP2A-B55 inhibition by FAM122A are key mitosis-inducing events
Published in The EMBO journal (20-02-2024)“…Abstract Entry into mitosis has been classically attributed to the activation of a cyclin B/Cdk1 amplification loop via a partial pool of this kinase becoming…”
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16
Structural, enzymatic and spatiotemporal regulation of PP2A-B55 phosphatase in the control of mitosis
Published in Frontiers in cell and developmental biology (29-08-2022)“…Cells require major physical changes to induce a proper repartition of the DNA. Nuclear envelope breakdown, DNA condensation and spindle formation are promoted…”
Get full text
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17
Region based memetic algorithm for real-parameter optimisation
Published in Information sciences (20-03-2014)“…Memetic algorithms with an appropriate trade-off between the exploration and exploitation can obtain very good results in continuous optimisation. That implies…”
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18
Microtubule Dynamics Scale with Cell Size to Set Spindle Length and Assembly Timing
Published in Developmental cell (21-05-2018)“…Successive cell divisions during embryonic cleavage create increasingly smaller cells, so intracellular structures must adapt accordingly. Mitotic spindle size…”
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19
A Family of Protein-Deglutamylating Enzymes Associated with Neurodegeneration
Published in Cell (12-11-2010)“…Polyglutamylation is a posttranslational modification that generates glutamate side chains on tubulins and other proteins. Although this modification has been…”
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20
In Vitro Reconstitution of Dynein Force Exertion in a Bulk Viscous Medium
Published in Current biology (01-11-2020)Get full text
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