Search Results - "Lacraz, G"

IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat by Ehses, J.A, Lacraz, G, Giroix, M.-H, Schmidlin, F, Coulaud, J, Kassis, N, Irminger, J.-C, Kergoat, M, Portha, B, Homo-Delarche, F, Donath, M.Y

“…Recent studies suggest an inflammatory process, characterized by local cytokine/chemokine production and immune cell infiltration, regulates islet dysfunction…”
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The GK rat beta-cell: A prototype for the diseased human beta-cell in type 2 diabetes? by Portha, B., Lacraz, G., Kergoat, M., Homo-Delarche, F., Giroix, M.-H., Bailbé, D., Gangnerau, M.-N., Dolz, M., Tourrel-Cuzin, C., Movassat, J.

“…Increasing evidence indicates that decreased functional beta-cell mass is the hallmark of type 2 diabetes (T2D) mellitus. Nowadays, the debate focuses on the…”
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P255 A PATHOGENIC ROLE FOR IL-15 IN FATTY LIVER DISEASE by Cepero-Donates, Y, Lacraz, G, Mayhue, M, Ramanathan, S, Ilangumaran, S

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Hypercholesterolaemia, signs of islet microangiopathy and altered angiogenesis precede onset of type 2 diabetes in the Goto–Kakizaki (GK) rat by Giroix, M-H., Irminger, J-C., Lacraz, G., Noll, C., Calderari, S., Ehses, J. A., Coulaud, J., Cornut, M., Kassis, N., Schmidlin, F., Paul, J-L., Kergoat, M., Janel, N., Halban, P. A., Homo-Delarche, F.

“…Aims/hypothesis The adult non-obese Goto–Kakizaki (GK) rat model of type 2 diabetes, particularly females, carries in addition to hyperglycaemia a genetic…”
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Lack of starvation-induced activation of AMP-activated protein kinase in the hypothalamus of the Lou/C rats resistant to obesity by Taleux, N, Potter, I. de, Deransart, C, Lacraz, G, Favier, R, Leverve, X.M, Hue, L, Guigas, B

“…Objective: The AMP-activated protein kinase (AMPK) is involved in the control of food intake by the hypothalamus. The aim of this work was to investigate if…”
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Liver mitochondrial properties from the obesity-resistant Lou/C rat by Lacraz, G, Couturier, K, Taleux, N, Servais, S, Sibille, B, Letexier, D, Guigas, B, Dubouchaud, H, Leverve, X, Favier, R

“…Objective: The first objective was to evaluate the influence of caloric intake on liver mitochondrial properties. The second objective was aimed at determining…”
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O8 Signes précoces de microangiopathie dans les îlots pancréatiques du rat GK, modèle spontané de diabète de type 2 (DT2) by Giroix, M.H, Homo-Delarche, F, Lacraz, G, Cornut, M, Coulaud, J, Irminger, J.C

“…Introduction La microangiopathie diabétique est reconnue au niveau rénal et oculaire, mais pas encore au niveau de l’îlot bien qu’une réaction inflammatoire…”
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P61 Chez le rat diabétique GK, les cellules β pancréatiques présentent une résistance inattendue au stress oxydant by Lacraz, G, Kassis, N, Galinier, A, Corinne, L, Bailbé, D, Portha, B

“…Introduction De fortes présomptions désignent l’hyperglycémie chronique comme agent causal direct des anomalies de la cellule β diabétique. Des preuves de…”
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P54 L’endothélium, principal responsable de l’inflammation de l’îlot pancréatique chez le rat GK, modèle spontané de diabète de type 2 (DT2) ? by Giroix, M.H, Lacraz, G, Ehses, J.A, Kassis, N, Coulaud, J, Portha, B, Donath, M.Y, Homo-Delarche, F

“…Introduction Un syndrome inflammatoire infraclinique circulant est associé au DT2 et, récemment, une réaction inflammatoire insulaire a été identifiée chez des…”
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