Search Results - "Lacolley, Patrick"

Vascular Smooth Muscle Cells and Arterial Stiffening: Relevance in Development, Aging, and Disease by Lacolley, Patrick, Regnault, Véronique, Segers, Patrick, Laurent, Stéphane

“…The cushioning function of large arteries encompasses distension during systole and recoil during diastole which transforms pulsatile flow into a steady flow…”
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Smooth muscle cell and arterial aging: basic and clinical aspects by Lacolley, Patrick, Regnault, Veronique, Avolio, Alberto P

“…Abstract Arterial aging engages a plethora of key signalling pathways that act in concert to induce vascular smooth muscle cell (VSMC) phenotypic changes…”
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Arterial Stiffness: From Basic Primers to Integrative Physiology by Regnault, Véronique, Lacolley, Patrick, Laurent, Stéphane

“…The elastic properties of conductance arteries are one of the most important hemodynamic functions in the body, and data continue to emerge regarding the…”
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Arterial Stiffness in Hypertension and Function of Large Arteries by Zhang, Yi, Lacolley, Patrick, Protogerou, Athanase D, Safar, Michel E

“…Abstract BACKGROUND Arterial stiffness—typically assessed from non-invasive measurement of pulse wave velocity along a straight portion of the vascular tree…”
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Targeting vascular smooth muscle cell to improve arterial stiffness by Lacolley, Patrick

“…Hypertension and arterial aging engage a plethora of key signaling pathways that act in concert to induce vascular smooth muscle cell (VSMC) phenotypic changes…”
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Galectin-3 Mediates Aldosterone-Induced Vascular Fibrosis by Calvier, Laurent, Miana, Maria, Reboul, Pascal, Cachofeiro, Victoria, Martinez-Martinez, Ernesto, de Boer, Rudolf A, Poirier, Françoise, Lacolley, Patrick, Zannad, Faiez, Rossignol, Patrick, López-Andrés, Natalia

“…OBJECTIVE—Aldosterone (Aldo) is involved in arterial stiffness and heart failure, but the mechanisms have remained unclear. Galectin-3 (Gal-3), a…”
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International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease by Olivera, Pablo A., Zuily, Stephane, Kotze, Paulo G., Regnault, Veronique, Al Awadhi, Sameer, Bossuyt, Peter, Gearry, Richard B., Ghosh, Subrata, Kobayashi, Taku, Lacolley, Patrick, Louis, Edouard, Magro, Fernando, Ng, Siew C., Papa, Alfredo, Raine, Tim, Teixeira, Fabio V., Rubin, David T., Danese, Silvio, Peyrin-Biroulet, Laurent

“…Patients with inflammatory bowel disease (IBD) are at increased risk of thrombotic events. Therapies for IBD have the potential to modulate this risk. The aims…”
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Elastase and exacerbation of neutrophil innate immunity are involved in multi‐visceral manifestations of COVID‐19 by Guéant, Jean‐Louis, Guéant‐Rodriguez, Rosa‐Maria, Fromonot, Julien, Oussalah, Abderrahim, Louis, Huguette, Chery, Celine, Gette, Mickael, Gleye, Stanislas, Callet, Jonas, Raso, Jeremie, Blanchecotte, François, Lacolley, Patrick, Guieu, Régis, Regnault, Véronique

“…Background Many arguments suggest that neutrophils could play a prominent role in COVID‐19. However, the role of key components of neutrophil innate immunity…”
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Vimentin as a target for the treatment of COVID-19 by Li, Zhenlin, Paulin, Denise, Lacolley, Patrick, Coletti, Dario, Agbulut, Onnik

“…We and others propose vimentin as a possible cellular target for the treatment of COVID-19. This innovative idea is so recent that it requires further…”
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Smooth Muscle Cell Mineralocorticoid Receptors Are Mandatory for Aldosterone–Salt to Induce Vascular Stiffness by Galmiche, Guillaume, Pizard, Anne, Gueret, Alexandre, El Moghrabi, Soumaya, Ouvrard-Pascaud, Antoine, Berger, Stefan, Challande, Pascal, Jaffe, Iris Z., Labat, Carlos, Lacolley, Patrick, Jaisser, Frédéric

“…Arterial stiffness is recognized as a risk factor for many cardiovascular diseases. Aldosterone via its binding to and activation of the mineralocorticoid…”
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Structural and Genetic Bases of Arterial Stiffness by Laurent, Stéphane, Boutouyrie, Pierre, Lacolley, Patrick

“…Arterial stiffness has independent predictive value for cardiovascular events. We review data concerning the heritability of arterial stiffness, and propose an…”
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Tribute to Michel E. Safar (1937–2024): A Groundbreaker in the Concept of Hypertension by Lacolley, Patrick, Struijker-Boudier, Harry, Regnault, Veronique, Barbier, Moyra

“…The authors present a short review of the personality, clinical and scientific contributions of a distinguished member of our Academy, the Artery Society and…”
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Sex Difference in Cardiovascular Risk by Regnault, Véronique, PhD, Thomas, Frédérique, PhD, Safar, Michel E., MD, Osborne-Pellegrin, Mary, PhD, Khalil, Raouf A., MD, Pannier, Bruno, MD, Lacolley, Patrick, MD

“…Objectives The study was to explore whether the brachial/carotid pulse pressure (B/C-PP) ratio selectively predicts the sex difference in age-related…”
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Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy by Esslinger, Ulrike, Garnier, Sophie, Korniat, Agathe, Proust, Carole, Kararigas, Georgios, Müller-Nurasyid, Martina, Empana, Jean-Philippe, Morley, Michael P, Perret, Claire, Stark, Klaus, Bick, Alexander G, Prasad, Sanjay K, Kriebel, Jennifer, Li, Jin, Tiret, Laurence, Strauch, Konstantin, O'Regan, Declan P, Marguiles, Kenneth B, Seidman, Jonathan G, Boutouyrie, Pierre, Lacolley, Patrick, Jouven, Xavier, Hengstenberg, Christian, Komajda, Michel, Hakonarson, Hakon, Isnard, Richard, Arbustini, Eloisa, Grallert, Harald, Cook, Stuart A, Seidman, Christine E, Regitz-Zagrosek, Vera, Cappola, Thomas P, Charron, Philippe, Cambien, François, Villard, Eric

“…Dilated cardiomyopathy (DCM) is an important cause of heart failure with a strong familial component. We performed an exome-wide array-based association study…”
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Systematic Review of Antiphospholipid Antibodies in COVID-19 Patients: Culprits or Bystanders? by Foret, Thomas, Dufrost, Virginie, Salomon Du Mont, Lucie, Costa, Patricia, Lefevre, Benjamin, Lacolley, Patrick, Regnault, Veronique, Zuily, Stephane, Wahl, Denis

“…Purpose of Review COVID-19 patients have a procoagulant state with a high prevalence of thrombotic events. The hypothesis of an involvement of antiphospholipid…”
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endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure by Cat, Aurelie Nguyen Dinh, Griol-Charhbili, Violaine, Loufrani, Laurent, Labat, Carlos, Benjamin, Laura, Farman, Nicolette, Lacolley, Patrick, Henrion, Daniel, Jaisser, Frederic

“…Pathophysiological aldosterone (aldo)/mineralocorticoid receptor (MR) signaling has significant effects on the cardiovascular system, resulting in hypertension…”
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Estrogen Receptor and Vascular Aging by Davezac, Morgane, Buscato, Melissa, Zahreddine, Rana, Lacolley, Patrick, Henrion, Daniel, Lenfant, Francoise, Arnal, Jean-Francois, Fontaine, Coralie

“…Cardiovascular diseases remain an age-related pathology in both men and women. These pathologies are 3-fold more frequent in men than in women before…”
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Cardiotrophin 1 Is Involved in Cardiac, Vascular, and Renal Fibrosis and Dysfunction by López-Andrés, Natalia, Rousseau, Amélie, Akhtar, Riaz, Calvier, Laurent, Iñigo, Carmen, Labat, Carlos, Zhao, Xuegen, Cruickshank, Kennedy, Díez, Javier, Zannad, Faiez, Lacolley, Patrick, Rossignol, Patrick

“…Cardiotrophin 1 (CT-1), a cytokine belonging to the interleukin 6 family, is increased in hypertension and in heart failure. We aimed to study the precise role…”
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Role of smooth muscle cell mineralocorticoid receptor in vascular tone by Tarjus, Antoine, Belozertseva, Ekaterina, Louis, Huguette, El Moghrabi, Soumaya, Labat, Carlos, Lacolley, Patrick, Jaisser, Frédéric, Galmiche, Guillaume

“…Identification of the mineralocorticoid receptor (MR) in the vasculature (i.e., endothelial and smooth muscle cells) raised the question of its role in…”
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Sodium Intake and Vascular Stiffness in Hypertension by Safar, Michel E, Temmar, Mohamed, Kakou, Augustine, Lacolley, Patrick, Thornton, Simon N

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