Search Results - "Lachant, Daniel"
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Chronic therapeutic anticoagulation is associated with decreased thrombotic complications in SARS‐CoV‐2 infection
Published in Journal of thrombosis and haemostasis (01-10-2020)“…Background Thrombotic disease complicates severe SARS‐CoV‐2 infection and is associated with increased morbidity and mortality. Various anticoagulation…”
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Pulmonary Hypertension: How to Best Treat the Different Scleroderma Phenotypes?
Published in Rheumatic diseases clinics of North America (01-05-2023)“…Pulmonary hypertension (PH) is a leading cause of morbidity and mortality in systemic sclerosis (SSc). PH is a heterogenous condition and several different…”
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Selexipag Use in Clinical Practice: Mind the Gap
Published in Chest (01-04-2020)Get full text
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Risk scores as a surrogate in pulmonary arterial hypertension: a different lens
Published in The lancet respiratory medicine (01-03-2024)Get full text
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Resting heart rate as a surrogate for improvement in intermediate risk pulmonary embolus patients?
Published in Respiratory medicine (01-10-2021)“…Pulmonary embolism (PE) response teams (PERT) have been developed to improve in-hospital mortality. Identifying intermediate risk PE patients that will…”
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Combination therapy improves vascular volume in female rats with pulmonary hypertension
Published in American journal of physiology. Lung cellular and molecular physiology (01-10-2019)“…Pulmonary arterial hypertension (PAH) is a female predominant disease in which progressive vascular remodeling and vasoconstriction result in right ventricular…”
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An untapped resource: characteristics of thrombus recovered from intermediate or high risk pulmonary embolus patients
Published in Cardiovascular pathology (01-03-2022)“…•Little is known about acute pulmonary embolism histology in survivors.•In thrombus obtained during acute embolectomy there was varying age of clots.•The age…”
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Cardiac effort and 6‐min walk distance correlate with stroke volume measured by cardiac magnetic resonance imaging
Published in Pulmonary circulation (01-04-2024)“…Right ventricular (RV) dysfunction in pulmonary arterial hypertension (PAH) is associated with poor outcomes. Cardiac magnetic resonance imaging (cMRI) is the…”
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CMV Encephalitis/Radiculitis: The Difficulty in Diagnosing in an Intubated Patient
Published in Case reports in critical care (2019)“…Cytomegalovirus (CMV) can cause severe disease including colitis, pneumonitis, and less commonly encephalitis, in profoundly immunocompromised individuals. CNS…”
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Nasopharyngeal viral PCR in immunosuppressed patients and its association with virus detection in bronchoalveolar lavage by PCR
Published in Respirology (Carlton, Vic.) (01-08-2017)“…ABSTRACT Background and objective Pulmonary infiltrates are common in immunosuppressed patients. Bronchoscopy with bronchoalveolar lavage (BAL) is often used…”
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Asymptomatic necrotizing myositis in a young male with progressive interstitial lung disease
Published in Respiratory medicine case reports (01-01-2021)“…Necrotizing autoimmune myopathy (NAM) is a rare inflammatory process characterized by bilateral proximal muscle weakness and elevated creatinine kinase levels…”
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12
Transitioning selexipag to oral treprostinil in patients with pulmonary artery hypertension
Published in Respiratory medicine case reports (01-01-2022)“…There are no prospective studies or guidelines describing transition between selexipag and oral treprostinil. We present two different transition strategies…”
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Direct oral anticoagulant therapy in patients with morbid obesity after intermediate- or high-risk pulmonary emboli
Published in ERJ open research (01-01-2021)“…There is little reported on the efficacy and safety of direct oral anticoagulants (DOACs) in morbid obesity after venous thromboembolism (VTE). In this…”
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Angiopoietin-2 and D-dimer add prognostic information to clinical risk in pulmonary arterial hypertension
Published in JHLT open (01-02-2025)“…Thrombosis and endothelial injury are pathologic hallmarks of pulmonary arterial hypertension (PAH). We aimed to evaluate whether markers of endothelial…”
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Evaluation of Clinical Recovery After Surgical Treatment for Hand Ischemia From Vasospastic and Occlusive Disease Using PROMIS
Published in Hand (New York, N.Y.) (01-01-2023)“…Background There is a paucity of literature describing the recovery trajectory after surgery for upper extremity ischemia. Using Patient-Reported Outcomes…”
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16
Heart rate monitoring improves clinical assessment during 6-min walk
Published in Pulmonary circulation (01-10-2020)“…Right ventricular (RV) function is a predictor of outcomes in pulmonary arterial hypertension (PAH). The 6-min walk test (6MWT) is likely an indirect measure…”
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The clinical impact of pneumocystis and viral PCR testing on bronchoalveolar lavage in immunosuppressed patients
Published in Respiratory medicine (01-12-2018)“…Pulmonary infiltrates in immunosuppressed patients are common. Yields from bronchoscopy with bronchoalveolar lavage (BAL) has been reported to be between 31…”
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Peak steps: Capacity for activity improves after adding approved therapy in pulmonary arterial hypertension
Published in Pulmonary circulation (01-07-2023)“…Pulmonary arterial hypertension (PAH) patients have low activity. Activity intensity or duration could be a measure of clinical status or improvement. We aimed…”
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Low dose monocrotaline causes a selective pulmonary vascular lesion in male and female pneumonectomized rats
Published in Experimental lung research (02-01-2018)“…Purpose/Aim: Low doses (30-80 mg/kg) of monocrotaline are commonly used to create experimental models of pulmonary hypertension in rats. At these doses,…”
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Pulmonary perfusion defects or residual vascular obstruction and persistent symptoms after pulmonary embolism: a systematic review and meta-analysis
Published in ERJ open research (01-07-2024)“…Up to 50% of pulmonary embolism (PE) patients have perfusion defects or residual vascular obstruction during follow-up despite adequate anticoagulant…”
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