Search Results - "Lacerda, Leandra Linhares"

Neutrophil extracellular trap-enriched supernatants carry microRNAs able to modulate TNF-α production by macrophages by Linhares-Lacerda, Leandra, Temerozo, Jairo Ramos, Ribeiro-Alves, Marcelo, Azevedo, Estefania P., Mojoli, Andres, Nascimento, Michelle T. C., Silva-Oliveira, Gustavo, Savino, Wilson, Foguel, Debora, Bou-Habib, Dumith Chequer, Saraiva, Elvira M.

“…Neutrophil extracellular traps (NETs) emerge from the cell as a DNA scaffold associated with cytoplasmic and granular proteins, able to immobilize and kill…”
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Peripheral nervous system is injured by neutrophil extracellular traps (NETs) elicited by nonstructural (NS) protein‐1 from Zika virus by Siqueira Santos, Raphael, Rochael, Natalia Cadaxo, Mattos, Thayana Roberta F., Fallett e Silva, Matheus Felipe, Linhares‐Lacerda, Leandra, Oliveira, Leandro Teixeira, Cunha, Marcela Sabino, Mohana‐Borges, Ronaldo, Gomes, Tiago Araujo, Barbosa‐Silva, Maria Carolina, Maron‐Gutierrez, Tatiana, Foguel, Debora, Saraiva, Elvira Maria

“…The involvement of innate immune mediators to the Zika virus (ZIKV)‐induced neuroinflammation is not yet well known. Here, we investigated whether neutrophil…”
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Circulating Plasma MicroRNA-208a as Potential Biomarker of Chronic Indeterminate Phase of Chagas Disease by Linhares-Lacerda, Leandra, Granato, Alessandra, Gomes-Neto, João Francisco, Conde, Luciana, Freire-de-Lima, Leonardo, de Freitas, Elisangela O, Freire-de-Lima, Celio G, Coutinho Barroso, Shana P, Jorge de Alcântara Guerra, Rodrigo, Pedrosa, Roberto C, Savino, Wilson, Morrot, Alexandre

“…Chagas cardiomyopathy is the most severe clinical manifestation of chronic Chagas disease. The disease affects most of the Latin American countries, being…”
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The role of TLR9 on Leishmania amazonensis infection and its influence on intranasal LaAg vaccine efficacy by Pratti, Juliana Elena Silveira, da Fonseca Martins, Alessandra Marcia, da Silva, Juliana Paiva, Ramos, Tadeu Diniz, Pereira, Joyce Carvalho, Firmino-Cruz, Luan, Oliveira-Maciel, Diogo, Vieira, Thiago Soares de Souza, Lacerda, Leandra Linhares, Vale, Andre Macedo, Freire-de-Lima, Celio G, Gomes, Daniel C Oliveira, Saraiva, Elvira M, Rossi-Bergmann, Bartira, de Matos Guedes, Herbert Leonel

“…Leishmania (L.) amazonensis is one of the etiological agents of cutaneous leishmaniasis (CL) in Brazil. Currently, there is no vaccine approved for human use…”
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'Leishmania infantum' axenic amastigotes induce human neutrophil extracellular traps and resist NET-mediated killing by Oliveira, Thamara K F, Oliveira-Silva, Jullyanna, Linhares-Lacerda, Leandra, da Silva Fraga-Junior, Vanderlei, Benjamim, Claudia F, Guimaraes-Costa, Anderson B, Saraiva, Elvira M

“…Neutrophils are multifaceted cells that, upon activation, release meshes of chromatin associated with different proteins, known as neutrophil extracellular…”
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Laminin Triggers Neutrophil Extracellular Traps (NETs) and Modulates NET Release Induced by Leishmania amazonensis by Silva-Oliveira, Gustavo, Linhares-Lacerda, Leandra, Mattos, Thayana R F, Sanches, Camila, Coelho-Sampaio, Tatiana, Riederer, Ingo, Saraiva, Elvira M

“…Neutrophils are recruited from the blood and transmigrate through the endothelium to reach tissues, where they are prone to respond through different…”
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Semaphorins and neuropilins: new players in the neuroendocrine control of the intrathymic T‐cell migration in humans by Mendes‐da‐Cruz, Daniella Arêas, Linhares‐Lacerda, Leandra, Smaniotto, Salete, Dardenne, Mireille, Savino, Wilson

“…Cell migration is a key event for proper intrathymic T‐cell differentiation, and several ligand–receptor interactions contribute to the well‐co ordinated…”
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Can thymic epithelial cells be infected by human T-lymphotropic virus type 1? by Moreira-Ramos, Klaysa, Castro, Flávia Madeira Monteiro de, Linhares-Lacerda, Leandra, Savino, Wilson

“…The human T-lymphotropic virus type-1 (HTLV-1) is the cause of adult T cell leukaemias/lymphoma. Because thymic epithelial cells (TEC) express recently defined…”
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Interleukin-27 Promotes Divergent Effects on HIV-1 Infection in Peripheral Blood Mononuclear Cells through BST-2/Tetherin by Temerozo, Jairo R, Ferreira, Pedro L C, Linhares-Lacerda, Leandra, Vieira, Rhaíssa C, Cister-Alves, Bruno, Gobbo, Livia, Ribeiro-Alves, Marcelo, Menna-Barreto, Rubem F S, Bou-Habib, Dumith Chequer

“…Interleukin-27 (IL-27) is able to inhibit HIV-1 replication in peripheral blood mononuclear cells (PBMCs), macrophages, and dendritic cells. Here, we identify…”
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Role of Small RNAs in Trypanosomatid Infections by Linhares-Lacerda, Leandra, Morrot, Alexandre

“…Trypanosomatid parasites survive and replicate in the host by using mechanisms that aim to establish a successful infection and ensure parasite survival…”
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ILeishmania infantum/I Axenic Amastigotes Induce Human Neutrophil Extracellular Traps and Resist NET-Mediated Killing by Oliveira, Thamara K. F, Oliveira-Silva, Jullyanna, Linhares-Lacerda, Leandra, da Silva Fraga-Junior, Vanderlei, Benjamim, Claudia F, Guimaraes-Costa, Anderson B, Saraiva, Elvira M

“…Neutrophils are multifaceted cells that, upon activation, release meshes of chromatin associated with different proteins, known as neutrophil extracellular…”
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HTLV-1-infected thymic epithelial cells convey the virus to CD4+ T lymphocytes by Carvalho Barros, Luciana Rodrigues, Linhares-Lacerda, Leandra, Moreira-Ramos, Klaysa, Ribeiro-Alves, Marcelo, Machado Motta, Maria Cristina, Bou-Habib, Dumith Chequer, Savino, Wilson

“…The human T-lymphotropic virus type-1 (HTLV-1) is the causative agent of adult T cell leukemia/lymphoma (ATL) and HTLV-1 associated myelopathy/tropical spastic…”
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Differential Expression of microRNAs in Thymic Epithelial Cells from Trypanosoma cruzi Acutely Infected Mice: Putative Role in Thymic Atrophy by Linhares-Lacerda, Leandra, Palu, Cintia Cristina, Ribeiro-Alves, Marcelo, Paredes, Bruno Diaz, Morrot, Alexandre, Garcia-Silva, Maria Rosa, Cayota, Alfonso, Savino, Wilson

“…A common feature seen in acute infections is a severe atrophy of the thymus. This occurs in the murine model of acute Chagas disease. Moreover, in thymuses…”
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HAM/TSP-derived HTLV-1-infected T cell lines promote morphological and functional changes in human astrocytes cell lines: possible role in the enhanced T cells recruitment into Central Nervous System by Gudo, Eduardo Samo, Silva-Barbosa, Suse Dayse, Linhares-Lacerda, Leandra, Ribeiro-Alves, Marcelo, Real, Suzana Corte, Bou-Habib, Dumith Chequer, Savino, Wilson

“…The mechanisms through which HTLV-1 leads to and maintains damage in the central nervous system of patients undergoing HTLV-1 associated myelopathy/tropical…”
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Can thymic epithelial cells be infected by human T-lymphotropic virus type 1? by Moreira-Ramos, Klaysa, Castro, Flávia, Linhares-Lacerda, Leandra, Savino, Wilson

“…The human T-lymphotropic virus type-1 (HTLV-1) is the cause of adult T cell leukaemias/lymphoma. Because thymic epithelial cells (TEC) express recently defined…”
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RNA interference-mediated knockdown of CD49e (α5 integrin chain) in human thymic epithelial cells modulates the expression of multiple genes and decreases thymocyte adhesion by Linhares-Lacerda, Leandra, Ribeiro-Alves, Marcelo, Nogueira, Ana Cristina Martins de Almeida, Mendes-da-Cruz, Daniella Areas, Magalhães, Danielle Aparecida, Dardenne, Mireille, Passos, Geraldo Aleixo, Savino, Wilson

“…The thymus is a central lymphoid organ, in which bone marrow-derived T cell precursors undergo a complex process of maturation. Developing thymocytes interact…”
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Laminin database: a tool to retrieve high-throughput and curated data for studies on laminins by Golbert, Daiane C.F, Linhares-Lacerda, Leandra, Almeida, Luiz G, Correa-de-Santana, Eliane, de Oliveira, Alice R, Mundstein, Alex S, Savino, Wilson, de Vasconcelos, Ana T.R

“…The Laminin(LM)-database, hosted at http://www.lm.lncc.br, is the first database focusing a non-collagenous extracellular matrix protein family, the LMs. Part…”
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Genetic modulation during thymocyte development an integrative approach based on microarray meta-analysis by Palu, Cintia C., Linhares-Lacerda, Leandra, Savino, Wilson, Ribeiro-Alves, Marcelo

“…The thymus is a primary lymphoid organ where T cell development takes place. The alpha-beta T lymphocyte lineage has well defined developmental stages, wherein…”
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An intronic variant in the TP53 gene in a Brazilian woman with breast cancer by Lacerda, Leandra Linhares, Serrano, Sergio Vicente, Mathes, Angelo, Rey, Juan A., Bello, Maria Josefa, Casartelli, Cacilda

“…We screened the TP53 gene for mutational status in 40 breast tumor cases by polymerase chain reaction, single-strand conformational polymorphism, and gene…”
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