Search Results - "Lacerda, Daniel I."

Design and synthesis of 3,4-methylenedioxy-6-nitrophenoxyacetylhydrazone derivatives obtained from natural safrole: New lead-agents with analgesic and antipyretic properties by Bezerra-Netto, Heleno J.C., Lacerda, Daniel I., Miranda, Ana Luisa P., Alves, Hélio M., Barreiro, Eliezer J., Fraga, Carlos A.M.

“…The discovery of the new powerful analgesic and long-lasting antipyretic N-acylhydrazone prototype LASSBio-891 is reported. In this work, we reported the…”
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Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl- N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors by Duarte, Carolina D., Tributino, Jorge L.M., Lacerda, Daniel I., Martins, Marina V., Alexandre-Moreira, Magna S., Dutra, Fernando, Bechara, Etelvino J.H., De-Paula, Francine S., Goulart, Marilia O.F., Ferreira, Juliano, Calixto, João B., Nunes, Marise P., Bertho, Alvaro L., Miranda, Ana Luisa P., Barreiro, Eliezer J., Fraga, Carlos A.M.

“…We describe herein the discovery of LASSBio-881 ( 3c) as a novel in vivo antinociceptive, anti-inflammatory, and in vitro antiproliferative and antioxidant…”
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