Search Results - "Lacave, Guillaume"
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Potentially modifiable factors contributing to sepsis-associated encephalopathy
Published in Intensive care medicine (01-08-2017)“…Purpose Identifying modifiable factors for sepsis-associated encephalopathy may help improve patient care and outcomes. Methods We conducted a retrospective…”
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Association between the Cardiac Arrest Hospital Prognosis (CAHP) score and reason for death after successfully resuscitated cardiac arrest
Published in Scientific reports (13-04-2023)“…Individualize treatment after cardiac arrest could potentiate future clinical trials selecting patients most likely to benefit from interventions. We assessed…”
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T-piece versus pressure-support ventilation for spontaneous breathing trials before extubation in patients at high risk of reintubation: protocol for a multicentre, randomised controlled trial (TIP-EX)
Published in BMJ open (24-11-2020)“…IntroductionIn intensive care unit (ICU), the decision of extubation is a critical time because mortality is particularly high in case of reintubation. To…”
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The Artificial Kidney Initiation in Kidney Injury 2 (AKIKI2): study protocol for a randomized controlled trial
Published in Current controlled trials in cardiovascular medicine (16-12-2019)“…The Artificial Kidney Initiation in Kidney Injury (AKIKI) trial showed that a delayed renal replacement therapy (RRT) strategy for severe acute kidney injury…”
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Effect of Drought Stress on Bioactives and Starch in Chilean Potato Landraces
Published in Potato research (01-09-2022)“…Despite the importance that environmental stress plays in the agronomic performance of plants, there is little agreement on its effect on bioactive compounds…”
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Early Active Mobilization during Mechanical Ventilation in the ICU
Published in The New England journal of medicine (10-11-2022)“…In this trial involving patients undergoing mechanical ventilation in the ICU, an increase in early mobilization did not improve the number of days alive and…”
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Effect of Postextubation High-Flow Nasal Oxygen With Noninvasive Ventilation vs High-Flow Nasal Oxygen Alone on Reintubation Among Patients at High Risk of Extubation Failure: A Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (15-10-2019)“…IMPORTANCE: High-flow nasal oxygen may prevent postextubation respiratory failure in the intensive care unit (ICU). The combination of high-flow nasal oxygen…”
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Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury (AKIKI 2): a multicentre, open-label, randomised, controlled trial
Published in The Lancet (British edition) (03-04-2021)“…Delaying renal replacement therapy (RRT) for some time in critically ill patients with severe acute kidney injury and no severe complication is safe and allows…”
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Spontaneous-Breathing Trials with Pressure-Support Ventilation or a T-Piece
Published in The New England journal of medicine (17-11-2022)“…Among patients with a high risk of reintubation, spontaneous-breathing trials performed with pressure-support ventilation did not result in significantly more…”
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Beneficial Effects of Noninvasive Ventilation after Extubation in Obese or Overweight Patients: A Post Hoc Analysis of a Randomized Clinical Trial
Published in American journal of respiratory and critical care medicine (15-02-2022)“…Although noninvasive ventilation (NIV) may prevent reintubation in patients at high risk of extubation failure in ICUs, this oxygenation strategy has not been…”
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Clinical characteristics and outcomes of immunocompromised critically ill patients with cytomegalovirus end-organ disease: a multicenter retrospective cohort study
Published in Critical care (London, England) (16-07-2024)“…Cytomegalovirus (CMV) infection in patients with cellular immune deficiencies is associated with significant morbidity and mortality. However, data on CMV…”
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Attributable mortality of ICU-acquired bloodstream infections: Impact of the source, causative micro-organism, resistance profile and antimicrobial therapy
Published in The Journal of infection (01-02-2017)“…Summary Objectives ICU-acquired bloodstream infection (ICU BSI) in Intensive Care unit (ICU) is still associated with a high mortality rate. The increase of…”
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Five days of postoperative antimicrobial therapy decreases infectious complications following pancreaticoduodenectomy in patients at risk for bile contamination
Published in HPB (Oxford, England) (01-06-2013)“…Abstract Objectives Pancreaticoduodenectomy (PD) is associated with high morbidity, in part as a result of infectious complications increased by preoperative…”
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Fluid Intake in Critically Ill Patients: The “Save Useless Fluids For Intensive Resuscitation” Multicenter Prospective Cohort Study
Published in Critical care medicine (01-11-2023)“…OBJECTIVES: Patients at risk of adverse effects related to positive fluid balance could benefit from fluid intake optimization. Less attention is paid to…”
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Fluid Intake in Critically Ill Patients: The "Save Useless Fluids For Intensive Resuscitation" Multicenter Prospective Cohort Study
Published in Critical care medicine (01-02-2024)“…Patients at risk of adverse effects related to positive fluid balance could benefit from fluid intake optimization. Less attention is paid to nonresuscitation…”
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Effect of Transfusion on Mortality and Other Adverse Events Among Critically Ill Septic Patients: An Observational Study Using a Marginal Structural Cox Model
Published in Critical care medicine (01-12-2017)“…OBJECTIVES:RBC transfusion is often required in patients with sepsis. However, adverse events have been associated with RBC transfusion, raising safety…”
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Spontaneous-Breathing Trials with Pressure-Support Ventilation or a T-Piece
Published in The New England journal of medicine (17-11-2022)“…Abstract Background Patients with acute respiratory failure caused by cardiogenic pulmonary edema (CPE) may require mechanical ventilation that can cause…”
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Clinical and biological clusters of sepsis patients using hierarchical clustering
Published in PloS one (04-08-2021)“…Background Heterogeneity in sepsis expression is multidimensional, including highly disparate data such as the underlying disorders, infection source,…”
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Treatment of positive catheter tip culture without bloodstream infections in critically ill patients. A case-cohort study from the OUTCOMEREA network
Published in Intensive care medicine (01-07-2024)“…Purpose This study aimed to evaluate the impact on subsequent infections and mortality of an adequate antimicrobial therapy within 48 h after catheter removal…”
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