Search Results - "Lacal, Jesús"

NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos cell death by Martínez-Morcillo, Francisco J, Cantón-Sandoval, Joaquín, Martínez-Navarro, Francisco J, Cabas, Isabel, Martínez-Vicente, Idoya, Armistead, Joy, Hatzold, Julia, López-Muñoz, Azucena, Martínez-Menchón, Teresa, Corbalán-Vélez, Raúl, Lacal, Jesús, Hammerschmidt, Matthias, García-Borrón, José C, García-Ayala, Alfonsa, Cayuela, María L, Pérez-Oliva, Ana B, García-Moreno, Diana, Mulero, Victoriano

“…Several studies have revealed a correlation between chronic inflammation and nicotinamide adenine dinucleotide (NAD+) metabolism, but the precise mechanism…”
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Bacterial Sensor Kinases: Diversity in the Recognition of Environmental Signals by KRELL, Tino, LACAL, Jesús, BUSCH, Andreas, SILVA-JIMENEZ, Hortencia, GUAZZARONI, María-Eugenia, LUIS RAMOS, Juan

“…Bacteria sense and respond to a wide range of physical and chemical signals. Central to sensing and responding to these signals are two-component systems,…”
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Evidence for chemoreceptors with bimodular ligand-binding regions harboring two signal-binding sites by Pineda-Molina, Estela, Reyes-Darias, José-Antonio, Lacal, Jesús, Ramos, Juan L, García-Ruiz, Juan Manuel, Gavira, Jose A, Krell, Tino

“…Chemoreceptor-based signaling is a central mechanism in bacterial signal transduction. Receptors are classified according to the size of their ligand-binding…”
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Bioavailability of pollutants and chemotaxis by Krell, Tino, Lacal, Jesús, Reyes-Darias, Jose Antonio, Jimenez-Sanchez, Celia, Sungthong, Rungroch, Ortega-Calvo, Jose Julio

“…Graphical abstract Highlights ► The exposure of bacteria to pollutants induces chemoattraction or chemorepellence. ► Pollutant chemoreceptors so far identified…”
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Sensing of environmental signals: classification of chemoreceptors according to the size of their ligand binding regions by Lacal, Jesús, García‐Fontana, Cristina, Muñoz‐Martínez, Francisco, Ramos, Juan‐Luis, Krell, Tino

“…Central to the different forms of taxis are methyl‐accepting chemotaxis proteins (MCPs). The increasing number of genome sequences reveals that MCPs differ…”
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Biomarker Landscape in RASopathies by Ferrito, Noemi, Báez-Flores, Juan, Rodríguez-Martín, Mario, Sastre-Rodríguez, Julián, Coppola, Alessio, Isidoro-García, María, Prieto-Matos, Pablo, Lacal, Jesus

“…RASopathies are a group of related genetic disorders caused by mutations in genes within the RAS/MAPK signaling pathway. This pathway is crucial for cell…”
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The Dictyostelium GSK3 kinase GlkA coordinates signal relay and chemotaxis in response to growth conditions by Lacal Romero, Jesus, Shen, Zhouxin, Baumgardner, Kimberly, Wei, Jing, Briggs, Steven P., Firtel, Richard A.

“…GSK3 plays a central role in orchestrating key biological signaling pathways, including cell migration. Here, we identify GlkA as a GSK3 family kinase with…”
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Dictyostelium discoideum as a non‐mammalian biomedical model by Martín‐González, Javier, Montero‐Bullón, Javier‐Fernando, Lacal, Jesus

“…This MS opens a window to the general audience on the potential of Dictyostelium as a model microbe in biomedicine. Summary Dictyostelium discoideum is one of…”
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Integrated in silico MS-based phosphoproteomics and network enrichment analysis of RASopathy proteins by Montero-Bullón, Javier-Fernando, González-Velasco, Ãscar, Isidoro-García, María, Lacal, Jesus

“…RASopathies are a group of syndromes showing clinical overlap caused by mutations in genes affecting the RAS-MAPK pathway. Consequent disruption on cellular…”
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The therapeutic potential of neurofibromin signaling pathways and binding partners by Báez-Flores, Juan, Rodríguez-Martín, Mario, Lacal, Jesus

“…Neurofibromin controls many cell processes, such as growth, learning, and memory. If neurofibromin is not working properly, it can lead to health problems,…”
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Identification of a Chemoreceptor for Tricarboxylic Acid Cycle Intermediates: DIFFERENTIAL CHEMOTACTIC RESPONSE TOWARDS RECEPTOR LIGANDS by Lacal, Jesús, Alfonso, Carlos, Liu, Xianxian, Parales, Rebecca E, Morel, Bertrand, Conejero-Lara, Francisco, Rivas, Germán, Duque, Estrella, Ramos, Juan L, Krell, Tino

“…We report the identification of McpS as the specific chemoreceptor for 6 tricarboxylic acid (TCA) cycle intermediates and butyrate in Pseudomonas putida. The…”
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Bacterial chemotaxis towards aromatic hydrocarbons in Pseudomonas by Lacal, Jesús, Muñoz-Martínez, Francisco, Reyes-Darías, José-Antonio, Duque, Estrella, Matilla, Miguel, Segura, Ana, Calvo, José-J. Ortega, Jímenez-Sánchez, Celía, Krell, Tino, Ramos, Juan L.

“…Summary Bacterial chemotaxis is an adaptive behaviour, which requires sophisticated information‐processing capabilities that cause motile bacteria to either…”
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Diversity at its best: bacterial taxis by Krell, Tino, Lacal, Jesús, Muñoz-Martínez, Francisco, Reyes-Darias, José Antonio, Cadirci, Bilge Hilal, García-Fontana, Cristina, Ramos, Juan Luis

“…Bacterial taxis is one of the most investigated signal transduction mechanisms. Studies of taxis have primarily used Escherichia coli and Salmonella as model…”
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Catabolite Repression of the TodS/TodT Two-Component System and Effector-Dependent Transphosphorylation of TodT as the Basis for Toluene Dioxygenase Catabolic Pathway Control by BUSCH, Andreas, LACAL, Jesús, SILVA-JIMENEZ, Hortencia, KRELL, Tino, RAMOS, Juan L

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Bacterial Sensor Kinase TodS Interacts with Agonistic and Antagonistic Signals by Busch, Andreas, Lacal, Jesús, Martos, Ariadna, Ramos, Juan L., Krell, Tino

“…The TodS/TodT two-component system controls expression of the toluene dioxygenase (TOD) pathway for the metabolism of toluene in Pseudomonas putida DOT-T1E…”
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Cardioprotective function of sclerostin by reducing calcium deposition, proliferation, and apoptosis in human vascular smooth muscle cells by González-Salvatierra, Sheila, García-Fontana, Cristina, Lacal, Jesus, Andújar-Vera, Francisco, Martínez-Heredia, Luis, Sanabria-de la Torre, Raquel, Ferrer-Millán, María, Moratalla-Aranda, Enrique, Muñoz-Torres, Manuel, García-Fontana, Beatriz

“…Sclerostin is an inhibitor of the Wnt/b-catenin pathway, which regulates bone formation, and can be expressed in vascular smooth muscle cells (VSMCs). Type 2…”
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Non-Mammalian Models for Understanding Neurological Defects in RASopathies by Rodríguez-Martín, Mario, Báez-Flores, Juan, Ribes, Vanessa, Isidoro-García, María, Lacal, Jesus, Prieto-Matos, Pablo

“…RASopathies, a group of neurodevelopmental congenital disorders stemming from mutations in the RAS/MAPK pathway, present a unique opportunity to delve into the…”
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Identification of Germinal Neurofibromin Hotspots by Lois, Sergio, Báez-Flores, Juan, Isidoro-García, María, Lacal, Jesus, Triviño, Juan Carlos

“…Neurofibromin is engaged in many cellular processes and when the proper protein functioning is impaired, it causes neurofibromatosis type 1 (NF1), one of the…”
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Proteomic and Transcriptomic Profiling Identifies Early Developmentally Regulated Proteins in Dictyostelium Discoideum by González-Velasco, Óscar, De Las Rivas, Javier, Lacal, Jesus

“…Cyclic AMP acts as a secondary messenger involving different cellular functions in eukaryotes. Here, proteomic and transcriptomic profiling has been combined…”
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Analysis of solvent tolerance in Pseudomonas putida DOT-T1E based on its genome sequence and a collection of mutants by Udaondo, Zulema, Duque, Estrella, Fernández, Matilde, Molina, Lázaro, Torre, Jesús de la, Bernal, Patricia, Niqui, José-Luis, Pini, Cecilia, Roca, Amalia, Matilla, Miguel A., Antonia Molina-Henares, M., Silva-Jiménez, Hortencia, Navarro-Avilés, Gloria, Busch, Andreas, Lacal, Jesús, Krell, Tino, Segura, Ana, Ramos, Juan-Luis

“…Pseudomonas putida strains are prevalent in a variety of pristine and polluted environments. The genome of the solvent-tolerant P. putida strain DOT-T1E which…”
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