Search Results - "Labyntsev, A J"
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EFFECT OF DIPHTHERIA TOXIN T-DOMAIN ON ENDOSOMAL pH
Published in Ukrainian biochemical journal (01-07-2015)“…A key step in the mode of cytotoxic action of diphtheria toxin (DT) is the transfer of its catalytic domain (Cd) from endosomes into the cytosol. The main…”
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Influence of human HB-EGF secreted form on cells with different EGFR and ErbB4 quantity
Published in Ukrainian biochemical journal (01-10-2019)“…HB-EGF is one of the most potent ligands of EGFR and ErbB4 receptors. This growth factor plays a pivotal role in many cellular processes, but its effect…”
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Enhancement of internalization of diphtheria toxin recombinant fragments in sensitive cells mediated by toxin’s T-domain
Published in Ukrainian biochemical journal (25-10-2017)“…Subunit B of diphtheria toxin (DT) and its R-domain differ by the presence of T-domain. The aim of the present work was to analyze the interaction of these…”
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Effect of the T-domain on intracellular transport of diphtheria toxin
Published in Ukrainian biochemical journal (01-05-2014)“…Subunit B of diphtheria toxin (DT), which consists of two domains: R (receptor-binding) and T (transmembrane), plays an important role in toxin-receptor…”
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Polyclonal antibodies against the human cell surface CD34 marker
Published in Cytology and genetics (2011)“…A highly efficient and inexpensive laboratory method of production and purification of polyclonal antibodies against the human cell surface CD34 marker was…”
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Study on toxin-neutralization properties of recombinant single-chain variable antibody’s fragments against diphtheria toxin B subunit
Published in Biopolimery i kletka (20-07-2009)Get full text
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Heparin-binding EGF-like growth factor: mechanisms of biological activity and potential therapeutic applications
Published in Ukrainian biochemical journal (23-10-2024)“…The diphtheria toxin receptor on sensitive mammalian cells is known as the membrane anchored precursor of heparin-binding EGF-like growth factor (HB-EGF). When…”
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Recombinant fluorescent models for studying the diphtheria toxin
Published in Russian journal of bioorganic chemistry (01-07-2014)“…Diphtheria toxin is a major factor of the pathogenicity of the causative agent of diphtheria Corynebacterium . Due to a small size, it is of considerable…”
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