Search Results - "Labrecque, Matthew T"
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Sex-Dependent effects of developmental arsenic exposure on methylation capacity and methylation regulation of the glucocorticoid receptor system in the embryonic mouse brain
Published in Toxicology reports (01-01-2015)“…Previously we have shown that prenatal moderate arsenic exposure (50 ppb) disrupts glucocorticoid receptor (GR) programming and that these changes continue…”
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Prenatal arsenic exposure alters the programming of the glucocorticoid signaling system during embryonic development
Published in Neurotoxicology and teratology (01-01-2015)“…Abstract The glucocorticoid system, which plays a critical role in a host of cellular functions including mood disorders and learning and memory, has been…”
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Perinatal exposure to 50ppb sodium arsenate induces hypothalamic-pituitary-adrenal axis dysregulation in male C57BL/6 mice
Published in Neurotoxicology (Park Forest South) (01-10-2012)“…► Perinatal arsenic exposure (PAE) induced multiple alterations in the HPA axis. ► PAE decreased hippocampal levels of 11β-HSD 1, a regulator of intracellular…”
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Prenatal arsenic exposure alters REST/NRSF and microRNA regulators of embryonic neural stem cell fate in a sex-dependent manner
Published in Neurotoxicology and teratology (01-01-2017)“…Abstract Exposure to arsenic, a common environmental toxin found in drinking water, leads to a host of neurological pathologies. We have previously…”
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Perinatal exposure to 50 ppb sodium arsenate induces hypothalamic-pituitary-adrenal axis dysregulation in male C57BL/6 mice
Published in Neurotoxicology (Park Forest South) (01-10-2012)“…Over the past two decades, key advancements have been made in understanding the complex pathology that occurs following not only high levels of arsenic…”
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The Impact of Prenatal Alcohol Exposure on Hippocampal-Dependent Outcome Measures is Influenced by Prenatal and Early-Life Rearing Conditions
Published in Alcoholism, clinical and experimental research (01-04-2015)“…Background The clinical course of individuals exposed to alcohol in utero is influenced by multiple factors, including the social environments of the gravid…”
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Reduced expression of MAPK/ERK genes in perinatal arsenic-exposed offspring induced by glucocorticoid receptor deficits
Published in Neurotoxicology and teratology (01-09-2011)“…Abstract Changes within the glucocorticoid receptor (GR) cellular signaling pathway were evaluated in adolescent mice exposed to 50 ppb arsenic during…”
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