Search Results - "Laboute, Thibaut"
-
1
Publisher Correction: Cryo-EM structure of human class C orphan GPCR GPR179 involved in visual processing
Published in Nature communications (21-10-2024)Get full text
Journal Article -
2
Cryo-EM structure of human class C orphan GPCR GPR179 involved in visual processing
Published in Nature communications (27-09-2024)“…GPR179, an orphan class C GPCR, is expressed at the dendritic tips of ON-bipolar cells in the retina. It plays a pivotal role in the initial synaptic…”
Get full text
Journal Article -
3
Facilitating mGluR4 activity reverses the long-term deleterious consequences of chronic morphine exposure in male mice
Published in Neuropsychopharmacology (01-06-2021)“…Understanding the neurobiological underpinnings of abstinence from drugs of abuse is critical to allow better recovery and ensure relapse prevention in…”
Get full text
Journal Article -
4
The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs
Published in eLife (31-01-2020)“…GPR88 is an orphan G protein-coupled receptor (GPCR) considered as a promising therapeutic target for neuropsychiatric disorders; its pharmacology, however,…”
Get full text
Journal Article -
5
Bispecific antibodies tethering innate receptors induce human tolerant-dendritic cells and regulatory T cells
Published in Frontiers in immunology (26-03-2024)“…There is an urgent need for alternative therapies targeting human dendritic cells (DCs) that could reverse inflammatory syndromes in many autoimmune and…”
Get full text
Journal Article -
6
Orphan receptor GPR158 serves as a metabotropic glycine receptor: mGlyR
Published in Science (American Association for the Advancement of Science) (31-03-2023)“…Glycine is a major neurotransmitter involved in several fundamental neuronal processes. The identity of the metabotropic receptor mediating slow…”
Get full text
Journal Article -
7
μ opioid receptor, social behaviour and autism spectrum disorder: reward matters
Published in British journal of pharmacology (01-07-2018)“…The endogenous opioid system is well known to relieve pain and underpin the rewarding properties of most drugs of abuse. Among opioid receptors, the μ receptor…”
Get full text
Journal Article -
8
Visualizing an orphan receptor GPR158 and it complex with neuronal regulator RGS7‐Gβ5 via cryoEM
Published in The FASEB journal (01-05-2022)“…G protein‐coupled receptors (GPCR) form the largest family of proteins (∼800 GPCRs) encoded in mammalian genomes that detect extracellular signals to program…”
Get full text
Journal Article -
9
Adhesion GPCR Latrophilin 3 regulates synaptic function of cone photoreceptors in a transsynaptic manner
Published in Proceedings of the National Academy of Sciences - PNAS (09-11-2021)“…Cone photoreceptors mediate daylight vision in vertebrates. Changes in neurotransmitter release at cone synapses encode visual information and is subject to…”
Get full text
Journal Article -
10
Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179
Published in Science signaling (25-07-2023)“…Precise synapse formation is essential for normal functioning of the nervous system. Retinal photoreceptors establish selective contacts with bipolar cells,…”
Get more information
Journal Article -
11
Adhesion GPCR Latrophilin 3 regulates synaptic function of cone photoreceptors in a trans-synaptic manner
Published in Proceedings of the National Academy of Sciences - PNAS (09-11-2021)“…Cone photoreceptors mediate daylight vision in vertebrates. Changes in neurotransmitter release at cone synapses encode visual information and is subject to…”
Get full text
Journal Article -
12
Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex
Published in Science (American Association for the Advancement of Science) (07-01-2022)“…GPR158 is an orphan G protein–coupled receptor (GPCR) highly expressed in the brain, where it controls synapse formation and function. GPR158 has also been…”
Get full text
Journal Article