Search Results - "Labeur, Marta"

Migratory Activity and Functional Changes of Green Fluorescent Effector Cells before and during Experimental Autoimmune Encephalomyelitis by Flügel, Alexander, Berkowicz, Tomasz, Ritter, Thomas, Labeur, Marta, Jenne, Dieter E, Li, Zhaoxia, Ellwart, Joachim W, Willem, Michael, Lassmann, Hans, Wekerle, Hartmut

“…Homing behavior and function of autoimmune CD4 + T cells in vivo was analyzed before and during EAE, using MBP-specific T cells retrovirally engineered to…”
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Retinoic Acid as a Novel Medical Therapy for Cushing’s Disease in Dogs by Castillo, Victor, Giacomini, Damiana, Páez-Pereda, Marcelo, Stalla, Johanna, Labeur, Marta, Theodoropoulou, Marily, Holsboer, Florian, Grossman, Ashley B, Stalla, Günter K, Arzt, Eduardo

“…Cushing’s disease is almost always caused by an ACTH-secreting pituitary tumor, but effective medical therapy is currently limited. Because retinoic acid has…”
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Generation of Tumor Immunity by Bone Marrow-Derived Dendritic Cells Correlates with Dendritic Cell Maturation Stage by Labeur, Marta S, Roters, Berthold, Pers, Birgit, Mehling, Annette, Luger, Thomas A, Schwarz, Thomas, Grabbe, Stephan

“…Bone marrow-derived dendritic cells (BmDC) are potent APC and can promote antitumor immunity in mice when pulsed with tumor Ag. This study aimed to define the…”
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Bone Morphogenetic Protein-4 Inhibits Corticotroph Tumor Cells: Involvement in the Retinoic Acid Inhibitory Action by Giacomini, Damiana, Páez-Pereda, Marcelo, Theodoropoulou, Marily, Labeur, Marta, Refojo, Damian, Gerez, Juan, Chervin, Alberto, Berner, Silvia, Losa, Marco, Buchfelder, Michael, Renner, Ulrich, Stalla, Günter K, Arzt, Eduardo

“…The molecular mechanisms governing the pathogenesis of ACTH-secreting pituitary adenomas are still obscure. Furthermore, the pharmacological treatment of these…”
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Regulation of pituitary function by cytokines by Haedo, Mariana R, Gerez, Juan, Fuertes, Mariana, Giacomini, Damiana, Páez-Pereda, Marcelo, Labeur, Marta, Renner, Ulrich, Stalla, Gunter K, Arzt, Eduardo

“…Research performed on the pituitary has proven that cytokines play an important role in maintaining pituitary physiology, affecting not only cell proliferation…”
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Interferon-γ inhibits cellular proliferation and ACTH production in corticotroph tumor cells through a novel janus kinases–signal transducer and activator of transcription 1/nuclear factor-kappa B inhibitory signaling pathway by Labeur, Marta, Refojo, Damian, Wölfel, Barbara, Stalla, Johanna, Vargas, Vivian, Theodoropoulou, Marily, Buchfelder, Michael, Paez-Pereda, Marcelo, Arzt, Eduardo, Stalla, Günter K

“…Interferon-γ (IFNG) is a cytokine that exerts potent antiproliferative and tumoricidal effects in a variety of cancers. Moreover, IFNG modulates normal…”
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Potential of retinoic acid derivatives for the treatment of corticotroph pituitary adenomas by Labeur, Marta, Paez-Pereda, Marcelo, Arzt, Eduardo, Stalla, Günter K.

“…Cushing’s disease is a severe clinical condition caused by hypersecretion of corticosteroids due to excessive ACTH secretion from a pituitary adenoma. This…”
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NOD2 receptors in adenopituitary folliculostellate cells: expression and function by Correa-de-Santana, Eliane, Fröhlich, Bianca, Labeur, Marta, Páez-Pereda, Marcelo, Theodoropoulou, Marily, Monteserin, Jose Luis, Renner, Ulrich, Stalla, Günter K

“…Folliculostellate cells (FS cells) are non-endocrine cells from the pituitary gland that respond to bacterial endotoxins by producing cytokines. In immune…”
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Nur77 induction and activation are necessary for interleukin-1 stimulation of proopiomelanocortin in AtT-20 corticotrophs by Kovalovsky, Damian, Paez Pereda, Marcelo, Labeur, Marta, Renner, Ulrich, Holsboer, Florian, Stalla, Günter K, Arzt, Eduardo

“…Nur77 and Nurr1 are critical for proopiomelanocortin (POMC) regulation by corticotrophin releasing hormone (CRH) in corticotrophs. We analyze the regulation…”
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Bone morphogenetic protein-4 control of pituitary pathophysiology by Giacomini, Damiana, Páez-Pereda, Marcelo, Theodoropoulou, Marily, Gerez, Juan, Nagashima, Alberto Carbia, Chervin, Alberto, Berner, Silvia, Labeur, Marta, Refojo, Damian, Renner, Ulrich, Stalla, Günter K, Arzt, Eduardo

“…Bone morphogenetic protein-4 (BMP-4), a member of the transforming growth factor-Beta(TGF-Beta) family, is overexpressed in different prolactinoma models and…”
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Long-Term Intracerebroventricular Infusion of Corticotropin-Releasing Hormone Alters Neuroendocrine, Neurochemical, Autonomic, Behavioral, and Cytokine Responses to a Systemic Inflammatory Challenge by Linthorst, Astrid C. E, Flachskamm, Cornelia, Hopkins, Stephen J, Hoadley, Margaret E, Labeur, MartaS, Holsboer, Florian, Reul, Johannes M. H. M

“…Corticotropin-releasing hormone (CRH) was infused intracerebroventricularly into rats for 7 d via a miniosmotic pump (1 microg . microl-1 . hr-1). Body…”
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High-throughput screening of glucocorticoid-induced enhancer activity reveals mechanisms of stress-related psychiatric disorders by Penner-Goeke, Signe, Bothe, Melissa, Rek, Nils, Kreitmaier, Peter, Pöhlchen, Dorothee, Kühnel, Anne, Glaser, Laura V, Kaya, Ezgi, Krontira, Anthi C, Röh, Simone, Czamara, Darina, Ködel, Maik, Monteserin-Garcia, Jose, Diener, Laura, Wölfel, Barbara, Sauer, Susann, Rummel, Christine, Riesenberg, Stephan, Arloth-Knauer, Janine, Ziller, Michael, Labeur, Marta, Meijsing, Sebastiaan, Binder, Elisabeth B

“…Exposure to stressful life events increases the risk for psychiatric disorders. Mechanistic insight into the genetic factors moderating the impact of stress…”
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Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression by Krontira, Anthi C, Cruceanu, Cristiana, Dony, Leander, Kyrousi, Christina, Link, Marie-Helen, Rek, Nils, Pöhlchen, Dorothee, Raimundo, Catarina, Penner-Goeke, Signe, Schowe, Alicia, Czamara, Darina, Lahti-Pulkkinen, Marius, Sammallahti, Sara, Wolford, Elina, Heinonen, Kati, Roeh, Simone, Sportelli, Vincenza, Wölfel, Barbara, Ködel, Maik, Sauer, Susann, Rex-Haffner, Monika, Räikkönen, Katri, Labeur, Marta, Cappello, Silvia, Binder, Elisabeth B

“…Glucocorticoids are important for proper organ maturation, and their levels are tightly regulated during development. Here, we use human cerebral organoids and…”
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TMEFF2 is an endogenous inhibitor of the CRH signal transduction pathway by Labeur, Marta, Wölfel, Barbara, Stalla, Johanna, Stalla, Günter K

“…TMEFF2 is a transmembrane protein with unknown function, containing an altered epidermal growth factor (EGF)-like motif, two follistatin-like domains, and a…”
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Molecular mechanisms of glucocorticoid receptor signaling by Labeur, Marta, Holsboer, Florian

“…This review highlights the most recent findings on the molecular mechanisms of the glucocorticoid receptor (GR). Most effects of glucocorticoids are mediated…”
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Pituitary tumors: Cell type-specific roles for BMP-4 by Labeur, Marta, Páez-Pereda, Marcelo, Haedo, Mariana, Arzt, Eduardo, Stalla, Günter K.

“…BMP-4 plays a crucial role not only in the formation of the anterior pituitary during embryo development but also in the pathogenesis of pituitary tumors in…”
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Effect of SOM230 (pasireotide) on corticotropic cells: action in dogs with Cushing's disease by Castillo, Victor, Theodoropoulou, Marily, Stalla, Johanna, Gallelli, Maria Florencia, Cabrera-Blatter, Maria Fernanda, Haedo, Mariana R, Labeur, Marta, Schmid, Herbert A, Stalla, Günter K, Arzt, Eduardo

“…SOM230 (pasireotide) is a multiligand somatostatin (SRIF) analog able to bind to somatostatin receptor (SSTR) subtypes 1, 2, 3 and 5, and trigger antisecretory…”
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Differential gene expression in models of pituitary prolactin-producing tumoral cells by Giacomini, Damiana, Haedo, Mariana, Gerez, Juan, Druker, Jimena, Páez-Pereda, Marcelo, Labeur, Marta, Stalla, Gunter K, Arzt, Eduardo

“…Although several genes and signalling pathways have been identified as important effectors in the development of pituitary tumours, our understanding of…”
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14. TLR4 and NOD innate immune receptors modulate the response of tumor pituitary AtT-20 cells through the PI3K/Akt survival pathway by Fröhlich, Bianca, Correa-de-Santana, Eliane, Theodoropoulou, Marily, Labeur, Marta, Paez-Pereda, Marcelo, Stalla, G.K, Renner, Ulrich

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Interferon-y inhibits cellular proliferation and ACTH production in corticotroph tumor cells through a novel janus kinases-signal transducer and activator of transcription 1/nuclear factor-kappa B inhibitory signaling pathway by LABEUR, Marta, REFOJO, Damian, WÖLFEL, Barbara, STALLA, Johanna, VARGAS, Vivian, THEODOROPOULOU, Marily, BUCHFELDER, Michael, PAEZ-PEREDA, Marcelo, ARZT, Eduardo, STALLA, Günter K

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