Search Results - "Labelle, Caroline"
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Genetic characterization of ABT-199 sensitivity in human AML
Published in Leukemia (01-01-2020)“…Acute myeloid leukemias (AML) with mutations in the NPM1 gene (NPM1c+) represent a large AML subgroup with varying response to conventional treatment,…”
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Enhancing the drug discovery process: Bayesian inference for the analysis and comparison of dose–response experiments
Published in Bioinformatics (15-07-2019)“…Abstract Motivation The efficacy of a chemical compound is often tested through dose–response experiments from which efficacy metrics, such as the IC50, can be…”
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Journal Article -
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Genetic Characterization of ABT-199 Sensitivity in Human AML
Published in Blood (29-11-2018)“…Acute myeloid leukemias (AML) are aggressive blood cancers characterized by an overall survival of 27% at 5 years. The main challenge in AML treatment…”
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Journal Article