Search Results - "Labeit, D."

Titin antibodies in “seronegative” myasthenia gravis — A new role for an old antigen by Stergiou, C, Lazaridis, K, Zouvelou, V, Tzartos, J, Mantegazza, R, Antozzi, C, Andreetta, F, Evoli, A, Deymeer, F, Saruhan-Direskeneli, G, Durmus, H, Brenner, T, Vaknin, A, Berrih-Aknin, S, Behin, A, Sharshar, T, De Baets, M, Losen, M, Martinez-Martinez, P, Kleopa, K.A, Zamba-Papanicolaou, E, Kyriakides, T, Kostera-Pruszczyk, A, Szczudlik, P, Szyluk, B, Lavrnic, D, Basta, I, Peric, S, Tallaksen, C, Maniaol, A, Gilhus, N.E, Casasnovas Pons, C, Pitha, J, Jakubíkova, M, Hanisch, F, Bogomolovas, J, Labeit, D, Labeit, S, Tzartos, S.J

“…Abstract Myasthenia gravis (MG) is an autoimmune disease caused by antibodies targeting the neuromuscular junction of skeletal muscles. Triple-seronegative MG…”
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Titin–Actin Interaction in Mouse Myocardium: Passive Tension Modulation and Its Regulation by Calcium/S100A1 by Yamasaki, R., Berri, M., Wu, Y., Trombitás, K., McNabb, M., Kellermayer, M.S.Z., Witt, C., Labeit, D., Labeit, S., Greaser, M., Granzier, H.

“…Passive tension in striated muscles derives primarily from the extension of the giant protein titin. However, several studies have suggested that, in cardiac…”
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Interaction Between PEVK-Titin and Actin Filaments: Origin of a Viscous Force Component in Cardiac Myofibrils by Kulke, M, Fujita-Becker, S, Rostkova, E, Neagoe, C, Labeit, D, Manstein, D J, Gautel, M, Linke, W A

“…The giant muscle protein titin contains a unique sequence, the PEVK domain, the elastic properties of which contribute to the mechanical behavior of relaxed…”
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Cardiac titin isoforms are coexpressed in the half-sarcomere and extend independently by Trombitás, K, Wu, Y, Labeit, D, Labeit, S, Granzier, H

“…Titin, the third myofilament type of cardiac muscle, contains a molecular spring segment that gives rise to passive forces in stretched myocardium and to…”
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PT105 The Mechanism of Parvovirus B19-Induced Dilated Cardiomyopathy in Mice by Bironaite, D, Bogomolovas, J, Simoliunas, E, Rinkunaite, I, Smalinskaite, L, Pogkopajev, A, Bukelskiene, V, Labeit, D, Labeit, S, Grabauskiene, V

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Tissue-specific expression and α-actinin binding properties of the Z-disc titin: implications for the nature of vertebrate Z-discs by Sorimachi, H, Freiburg, A, Kolmerer, B, Ishiura, S, Stier, G, Gregorio, C.C, Labeit, D, Linke, W.A, Suzuki, K, Labeit, S

“…Titins are giant filamentous proteins which connect Z-discs and M-lines in the sarcomeres of vertebrate striated muscles. Comparison of the N-terminal region…”
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Mechanical properties of titin isoforms by Granzier, H, Helmes, M, Cazorla, O, McNabb, M, Labeit, D, Wu, Y, Yamasaki, R, Redkar, A, Kellermayer, M, Labeit, S, Trombitás, K

“…Titin is a giant filamentous polypeptide of multi-domain construction spanning between the Z- and M-lines of the sarcomere. As a result of differential…”
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Calcium-Dependent Molecular Spring Elements in the Giant Protein Titin by Labeit, Dietmar, Watanabe, Kaori, Witt, Christian, Fujita, Hideaki, Wu, Yiming, Lahmers, Sunshine, Funck, Theodor, Labeit, Siegfried, Granzier, Henk

“…Titin (also known as connectin) is a giant protein with a wide range of cellular functions, including providing muscle cells with elasticity. Its physiological…”
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cDNA gene library shows new insights in the ultrastructure of the myometrium by Labeit, D.

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The Muscle Ankyrin Repeat Proteins: CARP, ankrd2/Arpp and DARP as a Family of Titin Filament-based Stress Response Molecules by Miller, Melanie K., Bang, Marie-Louise, Witt, Christian C., Labeit, Dietmar, Trombitas, Charles, Watanabe, Kaori, Granzier, Henk, McElhinny, Abigail S., Gregorio, Carol C., Labeit, Siegfried

“…CARP, ankrd-2/Arpp, and DARP, are three members of a conserved gene family, referred to here as MARPs (muscle ankyrin repeat proteins). The expression of MARPs…”
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MuRF1-dependent Regulation of Systemic Carbohydrate Metabolism as Revealed from Transgenic Mouse Studies by Hirner, Stephanie, Krohne, Christian, Schuster, Alexander, Hoffmann, Sigrid, Witt, Stephanie, Erber, Ralf, Sticht, Carsten, Gasch, Alexander, Labeit, Siegfried, Labeit, Dittmar

“…Under various pathophysiological muscle-wasting conditions, such as diabetes and starvation, a family of ubiquitin ligases, including muscle-specific…”
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The titin cDNA sequence and partial genomic sequences: insights into the molecular genetics, cell biology and physiology of the titin filament system by Kolmerer, B, Witt, C C, Freiburg, A, Millevoi, S, Stier, G, Sorimachi, H, Pelin, K, Carrier, L, Schwartz, K, Labeit, D, Gregorio, C C, Linke, W A, Labeit, S

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Association of the Chaperone αB-crystallin with Titin in Heart Muscle by Bullard, Belinda, Ferguson, Charles, Minajeva, Ave, Leake, Mark C., Gautel, Mathias, Labeit, Dietmar, Ding, Linlin, Labeit, Siegfried, Horwitz, Joseph, Leonard, Kevin R., Linke, Wolfgang A.

“…αB-crystallin, a major component of the vertebrate lens, is a chaperone belonging to the family of small heat shock proteins. These proteins form oligomers…”
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Changes in Titin and Collagen Underlie Diastolic Stiffness Diversity of Cardiac Muscle by Wu, Yiming, Cazorla, Olivier, Labeit, Dietmar, Labeit, Siegfried, Granzier, Henk

“…Small (N2B) and large (N2BA) cardiac titin isoforms are differentially expressed in a species-specific and heart location-specific manner. To understand how…”
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Molecular Mechanics of Cardiac Titin's PEVK and N2B Spring Elements by Watanabe, Kaori, Nair, Preetha, Labeit, Dietmar, Kellermayer, Miklós S.Z., Greaser, Marion, Labeit, Siegfried, Granzier, Henk

“…Titin is a giant elastic protein that is responsible for the majority of passive force generated by the myocardium. Titin's force is derived from its…”
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Specific interaction of the potassium channel β-subunit minK with the sarcomeric protein T-cap suggests a T-tubule-myofibril linking system by Furukawa, Tetsushi, Ono, Yasuko, Tsuchiya, Hiroyuki, Katayama, Yoshifumi, Bang, Marie-Louise, Labeit, Dietmar, Labeit, Siegfried, Inagaki, Nobuya, Gregorio, Carol C

“…Ion-channel β-subunits are ancillary proteins that co-assemble with α-subunits to modulate gating kinetics and enhance stability of multimeric channel…”
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Increased detection of HPV 16 virus in invasive, but not in early cervical cancers by Labeit, D, Back, W, von Weizsäcker, F, Hermann, P, Melchert, F, Leonard, K, Labeit, S

“…Human papilloma virus type 16 (HPV 16) DNA is found in about 50% of cervical squamous cell carcinomas (SCCs), and this association has raised the possibility…”
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Induction and Myofibrillar Targeting of CARP, and Suppression of the Nkx2.5 Pathway in the MDM Mouse with Impaired Titin-based Signaling by Witt, Christian C., Ono, Yasuko, Puschmann, Eva, McNabb, Mark, Wu, Yiming, Gotthardt, Michael, Witt, Stephanie H., Haak, Markus, Labeit, Dietmar, Gregorio, Carol C., Sorimachi, Hiroyuki, Granzier, Henk, Labeit, Siegfried

“…Muscular dystrophy with myositis ( mdm) is a recessive mouse mutation that is caused by a small deletion in the giant elastic muscle protein titin. Homozygous…”
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Titin isoform-dependent effect of calcium on passive myocardial tension by Fujita, Hideaki, Labeit, Dietmar, Gerull, Brenda, Labeit, Siegfried, Granzier, Henk L

“…We studied the effects of Ca2+ on titin (connectin)-based passive tension in skinned myocardium expressing either predominantly N2B titin (rat right ventricle,…”
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Einblicke in die Remodellierung des Myometriums während der Schwangerschaft by Labeit, D

“…Abstract only…”
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