Search Results - "Labeda, David P"

Diversity and abundance of phosphonate biosynthetic genes in nature by Yu, Xiaomin, Daraghazi, James R, Janga, Sarath C, Zhang, Jun Kai, Circello, Benjamin, Griffin, Benjamin M, Labeda, David P, Metcalf, William W

“…Phosphonates, molecules containing direct C-P bonds, comprise a structurally diverse class of natural products with interesting and useful biological…”
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Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes by Ju, Kou-San, Gao, Jiangtao, Doroghazi, James R., Wang, Kwo-Kwang A., Thibodeaux, Christopher J., Li, Steven, Metzger, Emily, Fudala, John, Su, Joleen, Zhang, Jun Kai, Lee, Jaeheon, Cioni, Joel P., Evans, Bradley S., Hirota, Ryuichi, Labeda, David P., van der Donk, Wilfred A., Metcalf, William W.

“…Although natural products have been a particularly rich source of human medicines, activity-based screening results in a very high rate of rediscovery of known…”
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Streptomyces aridus sp. nov., isolated from a high altitude Atacama Desert soil and emended description of Streptomyces noboritoensis Isono et al. 1957 by Idris, Hamidah, Labeda, David P., Nouioui, Imen, Castro, Jean Franco, del Carmen Montero-Calasanz, Maria, Bull, Alan T., Asenjo, Juan A., Goodfellow, Michael

“…A polyphasic study was undertaken to determine the taxonomic status of a Streptomyces strain which had been isolated from a high altitude Atacama Desert soil…”
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A Proteomic Survey of Nonribosomal Peptide and Polyketide Biosynthesis in Actinobacteria by Chen, Yunqiu, Ntai, Ioanna, Ju, Kou-San, Unger, Michelle, Zamdborg, Leonid, Robinson, Sarah J, Doroghazi, James R, Labeda, David P, Metcalf, William W, Kelleher, Neil L

“…Actinobacteria such as streptomycetes are renowned for their ability to produce bioactive natural products including nonribosomal peptides (NRPs) and…”
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Quinovosamycins: new tunicamycin-type antibiotics in which the α, β-1″,11′-linked N-acetylglucosamine residue is replaced by N-acetylquinovosamine by Price, Neil PJ, Labeda, David P, Naumann, Todd A, Vermillion, Karl E, Bowman, Michael J, Berhow, Mark A, Metcalf, William W, Bischoff, Kenneth M

“…Tunicamycins (TUN) are potent inhibitors of polyprenyl phosphate N -acetylhexosamine 1-phosphate transferases (PPHP), including essential eukaryotic GPT…”
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Multilocus sequence analysis of phytopathogenic species of the genus Streptomyces by Labeda, David P

“…The identification and classification of species within the genus Streptomyces is difficult because there are presently 576 species with validly published…”
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Genome sequences of three tunicamycin-producing Streptomyces strains, S. chartreusis NRRL 12338, S. chartreusis NRRL 3882, and S. lysosuperificus ATCC 31396 by Doroghazi, James R, Ju, Kou-San, Brown, Daren W, Labeda, David P, Deng, Zixin, Metcalf, William W, Chen, Wenqing, Price, Neil P.J

“…We announce the sequencing of Streptomyces chartreusis NRRL 12338 and NRRL 3882 and Streptomyces lysosuperificus ATCC 31396. These are producers of…”
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Taxonomic evaluation of putative Streptomyces scabiei strains held in the ARS Culture Collection (NRRL) using multi-locus sequence analysis by Labeda, David P

“…Multi-locus sequence analysis has been demonstrated to be a useful tool for identification of Streptomyces species and was previously applied to…”
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roadmap for natural product discovery based on large-scale genomics and metabolomics by Doroghazi, James R, Albright, Jessica C, Goering, Anthony W, Ju, Kou-San, Haines, Robert R, Tchalukov, Konstantin A, Labeda, David P, Kelleher, Neil L, Metcalf, William W

“…Actinobacteria encode a wealth of natural product biosynthetic gene clusters, whose systematic study is complicated by numerous repetitive motifs. By combining…”
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Phylogenetic relationships in the family Streptomycetaceae using multi-locus sequence analysis by Labeda, David P., Dunlap, Christopher A., Rong, Xiaoying, Huang, Ying, Doroghazi, James R., Ju, Kou-San, Metcalf, William W.

“…The family Streptomycetaceae , notably species in the genus Streptomyces , have long been the subject of investigation due to their well-known ability to…”
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Western Bats as a Reservoir of Novel Streptomyces Species with Antifungal Activity by Hamm, Paris S, Caimi, Nicole A, Northup, Diana E, Valdez, Ernest W, Buecher, Debbie C, Dunlap, Christopher A, Labeda, David P, Lueschow, Shiloh, Porras-Alfaro, Andrea

“…At least two-thirds of commercial antibiotics today are derived from , more specifically from the genus Antibiotic resistance and new emerging diseases pose…”
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Discovery of the Tyrobetaine Natural Products and Their Biosynthetic Gene Cluster via Metabologenomics by Parkinson, Elizabeth I, Tryon, James H, Goering, Anthony W, Ju, Kou-San, McClure, Ryan A, Kemball, Jeremy D, Zhukovsky, Sara, Labeda, David P, Thomson, Regan J, Kelleher, Neil L, Metcalf, William W

“…Natural products (NPs) are a rich source of medicines, but traditional discovery methods are often unsuccessful due to high rates of rediscovery. Genetic…”
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Streptomyces leeuwenhoekii sp. nov., the producer of chaxalactins and chaxamycins, forms a distinct branch in Streptomyces gene trees by Busarakam, Kanungnid, Bull, Alan T., Girard, Geneviève, Labeda, David P., van Wezel, Gilles P., Goodfellow, Michael

“…A polyphasic study was carried out to establish the taxonomic status of an Atacama Desert isolate, Streptomyces strain C34 T , which synthesises novel…”
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Streptomyces asenjonii sp. nov., isolated from hyper-arid Atacama Desert soils and emended description of Streptomyces viridosporus Pridham et al. 1958 by Goodfellow, Michael, Busarakam, Kanungnid, Idris, Hamidah, Labeda, David P., Nouioui, Imen, Brown, Roselyn, Kim, Byung-Yong, del Carmen Montero-Calasanz, Maria, Andrews, Barbara A., Bull, Alan T.

“…A polyphasic study was undertaken to establish the taxonomic status of Streptomyces strains isolated from hyper-arid Atacama Desert soils. Analysis of the 16S…”
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Entomopathogen ID: a curated sequence resource for entomopathogenic fungi by Dunlap, Christopher A., Ramirez, José Luis, Mascarin, Gabriel Moura, Labeda, David P.

“…We report the development of a publicly accessible, curated nucleotide sequence database of hypocrealean entomopathogenic fungi. The goal is to provide a…”
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Streptomyces odonnellii sp. nov., a proteolytic streptomycete isolated from soil under cerrado (savanna) vegetation cover by Pereira, Pedro Henrique Freitas, Macrae, Andrew, Reinert, Fernanda, de Souza, Rodrigo Fonseca, Coelho, Rosalie Reed Rodrigues, Pötter, Gabrielle, Klenk, Hans-Peter, Labeda, David P

“…A novel streptomycete, strain 594 , isolated from Brazilian soil collected under cerrado (savanna) vegetation cover is described. Strain 594 produced…”
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Streptomyces violaceusniger clade: a home for streptomycetes with rugose ornamented spores by Goodfellow, Michael, Kumar, Yashawant, Labeda, David P, Sembiring, Langkah

“…The taxonomic status of 16 strains received as Streptomyces hygroscopicus, Streptomyces melanosporofaciens, Streptomyces sparsogenes, Streptomyces…”
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Taxonomic evaluation of species in the Streptomyces hirsutus clade using multi-locus sequence analysis and proposals to reclassify several species in this clade by Labeda, David P, Rong, Xiaoying, Huang, Ying, Doroghazi, James R, Ju, Kou-San, Metcalf, William W

“…Previous phylogenetic analysis of species of the genus Streptomyces based on 16S rRNA gene sequences resulted in a statistically well-supported clade (100 %…”
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Streptomyces corynorhini sp. nov., isolated from Townsend’s big-eared bats (Corynorhinus townsendii) by Hamm, Paris S., Caimi, Nicole A., Northup, Diana E., Valdez, Ernest W., Buecher, Debbie C., Dunlap, Christopher A., Labeda, David P., Porras-Alfaro, Andrea

“…Four bacterial strains, with the capability of inhibiting Pseudogymnoascus destructans , the causative agent of white-nose syndrome, were isolated from male…”
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Evaluation of microbial strains for linoleic acid hydroxylation and reclassification of strain ALA2 by HOU, Ching T, LABEDA, David P, ROONEY, Alejandro

“…In previous studies, a new microbial strain ALA2 was isolated which produced many new products from linoleic acid [Gardner H.W., Hou C.T., Weisleder D. and…”
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