Gut Microbiota Dynamics in Relation to Long-COVID-19 Syndrome: Role of Probiotics to Combat Psychiatric Complications

Gut Microbiota Dynamics in Relation to Long-COVID-19 Syndrome: Role of Probiotics to Combat Psychiatric Complications

Increasing numbers of patients who recover from COVID-19 report lasting symptoms, such as fatigue, muscle weakness, dementia, and insomnia, known collectively as post-acute COVID syndrome or long COVID. These lasting symptoms have been examined in different studies and found to influence multiple or...

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Bibliographic Details
Published in:Metabolites Vol. 12; no. 10; p. 912
Main Authors: Alenazy, Maha F, Aljohar, Haya I, Alruwaili, Ashwag R, Daghestani, Maha H, Alonazi, Mona A, Labban, Ranyah S, El-Ansary, Afaf K, Balto, Hanan A
Format: Journal Article
Language:English
Published: Basel MDPI AG 27-09-2022
MDPI
Subjects:
Biomarkers
Cardiovascular disease
Coronaviruses
COVID-19
Cytokines
Dementia disorders
Disease transmission
Exocrine glands
Feces
gut microbiota
gut–organ axis
Health aspects
Infections
Inflammation
Intestinal microflora
Liver
long COVID-19
Microbiota
Microbiota (Symbiotic organisms)
Mortality
Oral hygiene
Ostomy
Pathogens
Patients
Permeability
Probiotics
psychiatric disorders
Review
Severe acute respiratory syndrome coronavirus 2
Sleep disorders
Viral infections
Saudi Arabia
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Summary:Increasing numbers of patients who recover from COVID-19 report lasting symptoms, such as fatigue, muscle weakness, dementia, and insomnia, known collectively as post-acute COVID syndrome or long COVID. These lasting symptoms have been examined in different studies and found to influence multiple organs, sometimes resulting in life-threating conditions. In this review, these symptoms are discussed in connection to the COVID-19 and long-COVID-19 immune changes, highlighting oral and psychiatric health, as this work focuses on the gut microbiota’s link to long-COVID-19 manifestations in the liver, heart, kidney, brain, and spleen. A model of this is presented to show the biological and clinical implications of gut microbiota in SARS-CoV-2 infection and how they could possibly affect the therapeutic aspects of the disease. Probiotics can support the body’s systems in fighting viral infections. This review focuses on current knowledge about the use of probiotics as adjuvant therapies for COVID-19 patients that might help to prevent long-COVID-19 complications.
Bibliography:ObjectType-Article-2
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ObjectType-Review-1
ISSN:2218-1989
2218-1989
DOI:10.3390/metabo12100912