Search Results - "Labat, Carlos"

Low salivary resolvin D1 to leukotriene B4 ratio predicts carotid intima media thickness: A novel biomarker of non-resolving vascular inflammation by Thul, Silke, Labat, Carlos, Temmar, Mohamed, Benetos, Athanase, Bäck, Magnus

“…Background Different lipid mediators may have opposing effects on vascular inflammation. For example, whereas leukotriene B4 (LTB4) transduces inflammation,…”
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Evidence for a Prognostic Role of Orthostatic Hypertension on Survival in a Very Old Institutionalized Population by Agnoletti, Davide, Valbusa, Filippo, Labat, Carlos, Gautier, Sylvie, Mourad, Jean-Jacques, Benetos, Athanase

“…In old individuals, regulation of blood pressure during postural changes is impaired. Several studies have assessed the clinical impact of orthostatic…”
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Smooth Muscle Cell Mineralocorticoid Receptors Are Mandatory for Aldosterone–Salt to Induce Vascular Stiffness by Galmiche, Guillaume, Pizard, Anne, Gueret, Alexandre, El Moghrabi, Soumaya, Ouvrard-Pascaud, Antoine, Berger, Stefan, Challande, Pascal, Jaffe, Iris Z., Labat, Carlos, Lacolley, Patrick, Jaisser, Frédéric

“…Arterial stiffness is recognized as a risk factor for many cardiovascular diseases. Aldosterone via its binding to and activation of the mineralocorticoid…”
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Tracking and fixed ranking of leukocyte telomere length across the adult life course by Benetos, Athanase, Kark, Jeremy D., Susser, Ezra, Kimura, Masayuki, Sinnreich, Ronit, Chen, Wei, Steenstrup, Troels, Christensen, Kaare, Herbig, Utz, von Bornemann Hjelmborg, Jacob, Srinivasan, Sathanur R., Berenson, Gerald S., Labat, Carlos, Aviv, Abraham

“…Summary Short leukocyte telomere length (LTL) is associated with atherosclerosis in adults and diminished survival in the elderly. LTL dynamics are defined by…”
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endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure by Cat, Aurelie Nguyen Dinh, Griol-Charhbili, Violaine, Loufrani, Laurent, Labat, Carlos, Benjamin, Laura, Farman, Nicolette, Lacolley, Patrick, Henrion, Daniel, Jaisser, Frederic

“…Pathophysiological aldosterone (aldo)/mineralocorticoid receptor (MR) signaling has significant effects on the cardiovascular system, resulting in hypertension…”
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Functional Impairment of Endothelial Colony Forming Cells (ECFC) in Patients with Severe Atherosclerotic Cardiovascular Disease (ASCVD) by Simoncini, Stéphanie, Toupance, Simon, Labat, Carlos, Gautier, Sylvie, Dumoulin, Chloé, Arnaud, Laurent, Stathopoulou, Maria G., Visvikis-Siest, Sophie, Rossi, Pascal M., Benetos, Athanase, Dignat-George, Françoise, Sabatier, Florence

“…Endothelial dysfunction is a key factor in atherosclerosis. However, the link between endothelial repair and severity of atherosclerotic cardiovascular disease…”
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Longitudinal Association of Telomere Dynamics with Obesity and Metabolic Disorders in Young Children by Toupance, Simon, Karampatsou, Sofia I, Labat, Carlos, Genitsaridi, Sofia-Maria, Tragomalou, Athanasia, Kassari, Penio, Soulis, George, Hollander, Allyson, Charmandari, Evangelia, Benetos, Athanase

“…In adults, short leukocyte telomere length (LTL) is associated with metabolic disorders, such as obesity and diabetes mellitus type 2. These associations could…”
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Cardiotrophin 1 Is Involved in Cardiac, Vascular, and Renal Fibrosis and Dysfunction by López-Andrés, Natalia, Rousseau, Amélie, Akhtar, Riaz, Calvier, Laurent, Iñigo, Carmen, Labat, Carlos, Zhao, Xuegen, Cruickshank, Kennedy, Díez, Javier, Zannad, Faiez, Lacolley, Patrick, Rossignol, Patrick

“…Cardiotrophin 1 (CT-1), a cytokine belonging to the interleukin 6 family, is increased in hypertension and in heart failure. We aimed to study the precise role…”
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Role of smooth muscle cell mineralocorticoid receptor in vascular tone by Tarjus, Antoine, Belozertseva, Ekaterina, Louis, Huguette, El Moghrabi, Soumaya, Labat, Carlos, Lacolley, Patrick, Jaisser, Frédéric, Galmiche, Guillaume

“…Identification of the mineralocorticoid receptor (MR) in the vasculature (i.e., endothelial and smooth muscle cells) raised the question of its role in…”
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Determinants of accelerated progression of arterial stiffness in normotensive subjects and in treated hypertensive subjects over a 6-year period by BENETOS, Athanase, ADAMOPOULOS, Chris, SAFAR, Michel, GUIZE, Louis, BUREAU, Jeanne-Marie, TEMMAR, Mohamed, LABAT, Carlos, BEAN, Kathryn, THOMAS, Frédérique, PANNIER, Bruno, ASMAR, Roland, ZUREIK, Mahmoud

“…Elastic artery stiffness, a result of arterial aging, is an independent indicator of cardiovascular risk. The aim of the present longitudinal study was to…”
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Chronic oxidative stress induces a tissue-specific reduction in telomere length in CAST/Ei mice by Cattan, Valerie, Mercier, Nathalie, Gardner, Jeffrey P., Regnault, Veronique, Labat, Carlos, Mäki-Jouppila, Jenni, Nzietchueng, Rosine, Benetos, Athanase, Kimura, Masayuki, Aviv, Abraham, Lacolley, Patrick

“…We examine whether increased oxidative stress in vivo promotes telomere shortening in CAST/Ei mice. We explored the effects of L-buthionine sulfoximine…”
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Do Arterial Hemodynamic Parameters Predict Cognitive Decline Over a Period of 2 Years in Individuals Older Than 80 Years Living in Nursing Homes? The PARTAGE Study by Watfa, Ghassan, MD, PhD, Benetos, Athanase, MD, PhD, Kearney-Schwartz, Anna, MD, Labat, Carlos, BSc, Gautier, Sylvie, MD, Hanon, Olivier, MD, PhD, Salvi, Paolo, MD, PhD, Joly, Laure, MD, PhD

“…Abstract Objectives Several studies have highlighted a link between vascular alterations and cognitive decline. The PARTAGE study showed that arterial…”
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Telomere Length in Valve Tissue Is Shorter in Individuals With Aortic Stenosis and in Calcified Valve Areas by Saraieva, Ilona, Benetos, Athanase, Labat, Carlos, Franco-Cereceda, Anders, Bäck, Magnus, Toupance, Simon

“…Short telomere length (TL) is associated with age-related diseases, in particular cardiovascular diseases. However, whether the onset and course of aortic…”
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Number and Replating Capacity of Endothelial Colony-Forming Cells are Telomere Length Dependent: Implication for Human Atherogenesis by Toupance, Simon, Simonici, Stéphanie, Labat, Carlos, Dumoulin, Chloé, Lai, Tsung-Po, Lakomy, Cécile, Regnault, Véronique, Lacolley, Patrick, Dignat George, Françoise, Sabatier, Florence, Aviv, Abraham, Benetos, Athanase

“…Background Short leukocyte telomere length (TL) is associated with atherosclerotic cardiovascular disease. Endothelial repair plays a key role in the…”
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Changes in aortic stiffness related to elastic fiber network anomalies in the Brown Norway rat during maturation and aging by Osborne-Pellegrin, Mary, Labat, Carlos, Mercier, Nathalie, Challande, Pascal, Lacolley, Patrick

“…Adult Brown Norway (BN) rats exhibit numerous internal elastic lamina (IEL) ruptures in the abdominal aorta (AA) and a lower aortic elastin-to-collagen ratio…”
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Increased microparticle production and impaired microvascular endothelial function in aldosterone-salt-treated rats: protective effects of polyphenols by López Andrés, Natalia, Tesse, Angela, Regnault, Véronique, Louis, Huguette, Cattan, Valérie, Thornton, Simon N, Labat, Carlos, Kakou, Agustine, Tual-Chalot, Simon, Faure, Sébastien, Challande, Pascale, Osborne-Pellegrin, Mary, Martínez, M Carmen, Lacolley, Patrick, Andriantsitohaina, Ramaroson

“…We aimed to characterize circulating microparticles in association with arterial stiffness, inflammation and endothelial dysfunction in…”
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Pulse Wave Velocity is Associated With 1-Year Cognitive Decline in the Elderly Older than 80 Years: The PARTAGE Study by Benetos, Athanase, MD, PhD, Watfa, Ghassan, MD, MSc, Hanon, Olivier, MD, PhD, Salvi, Paolo, MD, PhD, Fantin, Francesco, MD, Toulza, Olivier, MD, Manckoundia, Patrick, MD, PhD, Agnoletti, Davide, MD, Labat, Carlos, BSc, Gautier, Sylvie, MD

“…Abstract Objectives Studies have shown the importance of vascular risk factors in the pathogenesis and evolution of cognitive disorders and dementia especially…”
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TERC Variants Associated with Short Leukocyte Telomeres: Implication of Higher Early Life Leukocyte Telomere Attrition as Assessed by the Blood-and-Muscle Model by Toupance, Simon, Stathopoulou, Maria G, Petrelis, Alexandros M, Gorenjak, Vesna, Labat, Carlos, Lai, Tsung-Po, Visvikis-Siest, Sophie, Benetos, Athanase

“…Short leukocyte telomere length (LTL) is associated with atherosclerotic cardiovascular disease (ASCVD). Mendelian randomisation studies, using single…”
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Simultaneous characterization of metabolic, cardiac, vascular and renal phenotypes of lean and obese SHHF rats by Youcef, Gina, Olivier, Arnaud, L'Huillier, Clément P J, Labat, Carlos, Fay, Renaud, Tabcheh, Lina, Toupance, Simon, Rodriguez-Guéant, Rosa-Maria, Bergerot, Damien, Jaisser, Frédéric, Lacolley, Patrick, Zannad, Faiez, Laurent Vallar, Pizard, Anne

“…Individuals with metabolic syndrome (MetS) are prone to develop heart failure (HF). However, the deleterious effects of MetS on the continuum of events leading…”
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Klotho KL-VS genotype is involved in blood pressure regulation by Nzietchueng, Rosine, El Shamieh, Said, Benachour, Hamanou, Labat, Carlos, Herbeth, Bernard, Ndiaye, Ndeye Coumba, Masson, Christine, Visvikis-Siest, Sophie, Benetos, Athanase

“…Genome-wide linkage analysis studies reported the importance of the long arm of chromosome 13 in systolic blood pressure regulation. Therefore, isolating a…”
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