Search Results - "Labarre, Denis"
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Complement activation by core-shell poly(isobutylcyanoacrylate)-polysaccharide nanoparticles: influences of surface morphology, length, and type of polysaccharide
Published in Pharmaceutical research (01-06-2006)“…Biodistribution of intravenously administered nanoparticles depends on opsonization. The aim of this study was the evaluation of complement activation induced…”
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Journal Article -
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The Interactions between Blood and Polymeric Nanoparticles Depend on the Nature and Structure of the Hydrogel Covering the Surface
Published in Polymers (01-06-2012)“…Polymeric surfaces in contact with blood in vivo are foreign bodies and are quickly isolated from blood by the non-specific defense systems. Nanoparticles (NP)…”
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Journal Article Book Review -
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Design aspects of poly(alkylcyanoacrylate) nanoparticles for drug delivery
Published in Journal of drug targeting (01-01-2007)“…Poly(alkylcyanoacrylate) (PACA) nanoparticles were first developed 25 years ago taking advantage of the in vivo degradation potential of the polymer and of its…”
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4
Relationship between complement activation, cellular uptake and surface physicochemical aspects of novel PEG-modified nanocapsules
Published in Biomaterials (01-11-2001)“…The aim of our work was to examine the relationship between modifications of the surface of nanocapsules (NC) by adsorption or covalent grafting of…”
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5
Recanalization and particle exclusion after embolization of uterine arteries in sheep: a long-term study
Published in Fertility and sterility (01-03-2009)“…Objective To compare the long-term evolution of uterine arteries after embolization with the two most commonly used embolic agents for fibroid embolization:…”
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Journal Article Conference Proceeding -
6
Determination of scission, crosslinking and branching parameters of electron beam irradiated methacrylate–acrylamide copolymer
Published in Polymer degradation and stability (01-04-2009)“…The aim of this work was to investigate the impact of electron beam irradiation at different dose rates on the molecular structure of linear…”
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Journal Article -
7
Heparin coated poly(alkylcyanoacrylate) nanoparticles coupled to hemoglobin: a new oxygen carrier
Published in Biomaterials (01-07-2004)“…A new generation of drug delivery systems based on heparin–poly(isobutylcyanoacrylate) copolymers has been developed to carry hemoglobin. These copolymers…”
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Journal Article -
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Long-circulating nanoparticles bearing heparin or dextran covalently bound to poly(methyl methacrylate)
Published in Pharmaceutical research (01-07-1998)“…In a biomimetic approach to the development of drug carriers escaping early capture by phagocytes, nanoparticles made of amphiphilic copolymers of either…”
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Journal Article -
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MR Imaging Detection of Superparamagnetic Iron Oxide–loaded Tris-acryl Embolization Microspheres
Published in Journal of vascular and interventional radiology (01-10-2007)“…Purpose To assess by magnetic resonance (MR) imaging the detectability of superparamagnetic iron oxide (SPIO)-labeled microspheres (MSs) in vitro on gelose, ex…”
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10
Complement consumption by poly(ethylene glycol) in different conformations chemically coupled to poly(isobutyl 2-cyanoacrylate) nanoparticles
Published in Life sciences (1973) (1997)“…There is an increasing interest to develop injectable drug polymeric carriers not recognizable by the body as foreign particles and eliminated very quickly…”
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Journal Article -
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A novel injectable tissue adhesive based on oxidized dextran and chitosan
Published in Acta biomaterialia (15-04-2017)“…[Display omitted] A surgical adhesive that can be used in different surgical situations with or without sutures is a surgeons’ dream and yet none has been able…”
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12
Effect of PEO surface density on long-circulating PLA-PEO nanoparticles which are very low complement activators
Published in Biomaterials (1996)“…The rapid uptake of injected nanoparticles by cells of the mononuclear phagocytes system (MRS) is a major obstacle when a long blood circulation time is…”
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13
Tunable delivery of niflumic acid from resorbable embolization microspheres for uterine fibroid embolization
Published in International journal of pharmaceutics (10-09-2016)“…[Display omitted] Uterine arteries embolization (UAE) is a recent technique that aims, by means of particles injected percutaneously, to stifle fibroids…”
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Journal Article -
14
Poly(ethylene glycol) methacrylate hydrolyzable microspheres for transient vascular embolization
Published in Acta biomaterialia (01-03-2014)“…Poly(ethylene glycol) methacrylate (PEGMA) hydrolyzable microspheres intended for biomedical applications were readily prepared from poly(lactide-co-glycolide)…”
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Synthesis of hydrophilic intra-articular microspheres conjugated to ibuprofen and evaluation of anti-inflammatory activity on articular explants
Published in International journal of pharmaceutics (01-01-2014)“…The main limitation of current microspheres for intra-articular delivery of non-steroidal anti-inflammatory drugs (NSAIDs) is a significant initial burst…”
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Characterization of Dextran−Poly(isobutylcyanoacrylate) Copolymers Obtained by Redox Radical and Anionic Emulsion Polymerization
Published in Macromolecules (16-05-2006)“…Characteristics of polymer forming poly(isobutylcyanoacrylate) (PIBCA) nanoparticles used as drug delivery systems were investigated. The nanoparticles were…”
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Journal Article -
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Intra-articular fate of degradable poly(ethyleneglycol)-hydrogel microspheres as carriers for sustained drug delivery
Published in International journal of pharmaceutics (18-11-2013)“…A novel degradable microsphere (MS) for intra-articular drug delivery, composed of a polyethylene glycol (PEG) core containing degradable regions made of short…”
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Journal Article -
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Artificial oxygen carrier based on polysaccharides–poly(alkylcyanoacrylates) nanoparticle templates
Published in Biomaterials (01-08-2010)“…Abstract Biomimetic nanoparticles based on polysaccharides–poly(alkylcyanoacrylates) copolymers were initially developed in view of drug delivery. Core-shell…”
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Journal Article -
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Anti-angiogenic drug delivery from hydrophilic resorbable embolization microspheres: An in vitro study with sunitinib and bevacizumab
Published in International journal of pharmaceutics (30-04-2015)“…[Display omitted] Anti-angiogenic (AA) drugs are proposed as novel agents for targeted therapies in hepatocellular carcinoma (HCC). Loading of AA drugs into…”
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Journal Article -
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Properties of Polysaccharides Grafted on Nanoparticles Investigated by EPR
Published in Langmuir (06-06-2006)“…The in vivo fate of nanoparticles developed as drug delivery systems is influenced by the surface characteristics of the colloidal particles. In the present…”
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