Search Results - "Lab, Max J"

Loss of T-tubules and Other Changes to Surface Topography in Ventricular Myocytes from Failing Human and Rat Heart by Lyon, Alexander R., MacLeod, Ken T., Zhang, Yanjun, Garcia, Edwin, Kanda, Gaelle Kikonda, Lab, Max J., Korchev, Yuri E., Harding, Sian E., Gorelik, Julia, Marks, Andrew R.

“…T-tubular invaginations of the sarcolemma of ventricular cardiomyocytes contain junctional structures functionally coupling L-type calcium channels to the…”
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Microtubule-Dependent Mitochondria Alignment Regulates Calcium Release in Response to Nanomechanical Stimulus in Heart Myocytes by Miragoli, Michele, Sanchez-Alonso, Jose L., Bhargava, Anamika, Wright, Peter T., Sikkel, Markus, Schobesberger, Sophie, Diakonov, Ivan, Novak, Pavel, Castaldi, Alessandra, Cattaneo, Paola, Lyon, Alexander R., Lab, Max J., Gorelik, Julia

“…Arrhythmogenesis during heart failure is a major clinical problem. Regional electrical gradients produce arrhythmias, and cellular ionic transmembrane…”
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An alternative mechanism of clathrin-coated pit closure revealed by ion conductance microscopy by Shevchuk, Andrew I, Novak, Pavel, Taylor, Marcus, Diakonov, Ivan A, Ziyadeh-Isleem, Azza, Bitoun, Marc, Guicheney, Pascale, Lab, Max J, Gorelik, Julia, Merrifield, Christien J, Klenerman, David, Korchev, Yuri E

“…Current knowledge of the structural changes taking place during clathrin-mediated endocytosis is largely based on electron microscopy images of fixed…”
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Pathophysiology and prevention of atrial fibrillation by ALLESSIE, Maurits A, BOYDEN, Penelope A, WALDO, Albert L, CAMM, A. John, KLEBER, André G, LAB, Max J, LEGATO, Marianne J, ROSEN, Michael R, SCHWARTZ, Peter J, SPOONER, Peter M, VAN WAGONER, David R

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Scanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cells by Miragoli, Michele, Moshkov, Alexey, Novak, Pavel, Shevchuk, Andrew, Nikolaev, Viacheslav O., El-Hamamsy, Ismail, Potter, Claire M. F., Wright, Peter, Kadir, S.H. Sheikh Abdul, Lyon, Alexander R., Mitchell, Jane A., Chester, Adrian H., Klenerman, David, Lab, Max J., Korchev, Yuri E., Harding, Sian E., Gorelik, Julia

“…Cardiovascular diseases are complex pathologies that include alterations of various cell functions at the levels of intact tissue, single cells and subcellular…”
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Imaging Single Virus Particles on the Surface of Cell Membranes by High-Resolution Scanning Surface Confocal Microscopy by Shevchuk, Andrew I., Hobson, Phil, Lab, Max J., Klenerman, David, Krauzewicz, Nina, Korchev, Yuri E.

“…We have developed a high-resolution scanning surface confocal microscopy technique capable of imaging single virus-like particles (VLPs) on the surfaces of…”
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Endocytic pathways: combined scanning ion conductance and surface confocal microscopy study by Shevchuk, Andrew I., Hobson, Phil, Lab, Max J., Klenerman, David, Krauzewicz, Nina, Korchev, Yuri E.

“…We introduce a novel high resolution scanning surface confocal microscopy technique that enables imaging of endocytic pits in apical membranes of live cells…”
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Dynamic Assembly of Surface Structures in Living Cells by Gorelik, Julia, Shevchuk, Andrew I., Frolenkov, Gregory I., Diakonov, Ivan A., Lab, Max J., Kros, Corné J., Richardson, Guy P., Vodyanoy, Igor, Christopher R. W. Edwards, Klenerman, David, Korchev, Yuri E.

“…Although the dynamics of cell membranes and associated structures is vital for cell function, little is known due to lack of suitable methods. We found, using…”
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Imaging Proteins in Membranes of Living Cells by High-Resolution Scanning Ion Conductance Microscopy by Shevchuk, Andrew I., Frolenkov, Gregory I., Sánchez, Daniel, James, Peter S., Freedman, Noah, Lab, Max J., Jones, Roy, Klenerman, David, Korchev, Yuri E.

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Functional localization of single active ion channels on the surface of a living cell by Korchev, Yuri E, Negulyaev, Yuri A, Edwards, Christopher R.W, Vodyanoy, Igor, Lab, Max J

“…The spatial distribution of ion channels in the cell plasma membrane has an important role in governing regional specialization, providing a precise and…”
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Nanoscale live-cell imaging using hopping probe ion conductance microscopy by Frolenkov, Gregory I, Klenerman, David, Korchev, Yuri E, Novak, Pavel, Li, Chao, Shevchuk, Andrew I, Stepanyan, Ruben, Caldwell, Matthew, Hughes, Simon, Smart, Trevor G, Gorelik, Julia, Ostanin, Victor P, Lab, Max J, Moss, Guy W J

“…We describe hopping mode scanning ion conductance microscopy that allows noncontact imaging of the complex three-dimensional surfaces of live cells with…”
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Scanning Surface Confocal Microscopy for Simultaneous Topographical and Fluorescence Imaging: Application to Single Virus-like Particle Entry into a Cell by Gorelik, J., Shevchuk, A., Ramalho, M., Elliott, M., Lei, C., Higgins, C. F., Lab, Max J., Klenerman, D., Krauzewicz, N., Korchev, Y.

“…We have developed a method for simultaneous recording of high-resolution topography and cell surface fluorescence in a single scan which we call scanning…”
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Imaging Single Nanoparticle Interactions with Human Lung Cells Using Fast Ion Conductance Microscopy by Novak, Pavel, Shevchuk, Andrew, Ruenraroengsak, Pakatip, Miragoli, Michele, Thorley, Andrew J, Klenerman, David, Lab, Max J, Tetley, Teresa D, Gorelik, Julia, Korchev, Yuri E

“…Experimental data on dynamic interactions between individual nanoparticles and membrane processes at nanoscale, essential for biomedical applications of…”
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The use of scanning ion conductance microscopy to image A6 cells by Gorelik, Julia, Zhang, Yanjun, Shevchuk, Andrew I, Frolenkov, Gregory I, Sánchez, Daniel, Lab, Max J, Vodyanoy, Igor, Edwards, Christopher R.W, Klenerman, David, Korchev, Yuri E

“…Background: Continuous high spatial resolution observations of living A6 cells would greatly aid the elucidation of the relationship between structure and…”
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The scanning ion conductance microscope for cellular physiology by Lab, Max J, Bhargava, Anamika, Wright, Peter T, Gorelik, Julia

“…The quest for nonoptical imaging methods that can surmount light diffraction limits resulted in the development of scanning probe microscopes. However, most of…”
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Stretch-induced regional mechanoelectric dispersion and arrhythmia in the right ventricle of anesthetized lambs by Chen, Ruo L, Penny, Daniel J, Greve, Gottfried, Lab, Max J

“…Regional mechanical and electrophysiological changes accompany most ventricular arrhythmias and, it has been suggested, by mechanoelectric feedback. We…”
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Hybrid Scanning Ion Conductance and Scanning Near-Field Optical Microscopy for the Study of Living Cells by Korchev, Yuri E., Raval, Meera, Lab, Max J., Gorelik, Julia, Edwards, Christopher R.W., Rayment, Trevor, Klenerman, David

“…We have developed a hybrid scanning ion conductance and scanning near-field optical microscope for the study of living cells. The technique allows…”
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A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart by Miragoli, Michele, Kadir, Siti H. Sheikh Abdul, Sheppard, Mary N., Salvarani, Nicoló, Virta, Matilda, Wells, Sarah, Lab, Max J., Nikolaev, Viacheslav O., Moshkov, Alexey, Hague, William M., Rohr, Stephan, Williamson, Catherine, Gorelik, Julia

“…Intrahepatic cholestasis of pregnancy may be complicated by fetal arrhythmia, fetal hypoxia, preterm labor, and, in severe cases, intrauterine death. The…”
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Functional interaction between charged nanoparticles and cardiac tissue: a new paradigm for cardiac arrhythmia? by Miragoli, Michele, Novak, Pavel, Ruenraroengsak, Pakatip, Shevchuk, Andrew I, Korchev, Yuri E, Lab, Max J, Tetley, Teresa D, Gorelik, Julia

“…To investigate the effect of surface charge of therapeutic nanoparticles on sarcolemmal ionic homeostasis and the initiation of arrhythmias. Cultured neonatal…”
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Simultaneous measurement of Ca(2+) and cellular dynamics: Combined scanning ion conductance and optical microscopy to study contracting cardiac myocytes by Shevchuk, Andrew I, Gorelik, Julia, Harding, Sian E, Lab, Max J

“…We have developed a distnace modulated protocol for scanning ion conductance microscopy to provide a robuts and reliable distance control mechanism for imaging…”
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