Search Results - "Laast, Victoria A."
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Distinguishing Cystic Degeneration from Other Aging Lesions in the Adrenal Cortex of Sprague-Dawley Rats
Published in Toxicologic pathology (01-07-2014)“…Cystic degeneration of the adrenal cortex is a common age-related finding in the Sprague-Dawley (SD) rat strain occurring more frequently in females…”
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Proceedings of the 2012 National Toxicology Program Satellite Symposium
Published in Toxicologic pathology (01-02-2013)“…The 2012 annual National Toxicology Program (NTP) Satellite Symposium, entitled “Pathology Potpourri,” was held in Boston in advance of the Society of…”
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Regulatory Forum Opinion Piece: The Value of Publishing Negative Scientific Study Data
Published in Toxicologic pathology (01-10-2015)“…Historically it has been easier to publish positive scientific results than negative data not supporting the research hypothesis. This appears to be…”
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Tracking Epidermal Nerve Fiber Changes in Asian Macaques: Tools and Techniques for Quantitative Assessment
Published in Toxicologic pathology (01-08-2016)“…Quantitative assessment of epidermal nerve fibers (ENFs) has become a widely used clinical tool for the diagnosis of small fiber neuropathies such as diabetic…”
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Persistent Peripheral Nervous System Damage in Simian Immunodeficiency Virus—Infected Macaques Receiving Antiretroviral Therapy
Published in Journal of neuropathology and experimental neurology (01-11-2015)“…Human immunodeficiency virus (HIV)–induced peripheral neuropathy is the most common neurologic complication associated with HIV infection. In addition to…”
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Macrophage-Mediated Dorsal Root Ganglion Damage Precedes Altered Nerve Conduction in SIV-Infected Macaques
Published in The American journal of pathology (01-11-2011)“…Peripheral neuropathy is the most common neurological complication of HIV-1 infection, affecting over one-third of infected individuals, including those…”
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Neuroinflammation and Virus Replication in the Spinal Cord of Simian Immunodeficiency Virus–Infected Macaques
Published in Journal of neuropathology and experimental neurology (01-01-2015)“…ABSTRACTStudies of neurologic diseases induced by simian immunodeficiency virus (SIV) in Asian macaques have contributed greatly to the current understanding…”
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Occurrence of Spontaneous Amphophilic-Vacuolar Renal Tubule Tumors in Sprague-Dawley Rats from Subchronic Toxicity Studies
Published in Toxicologic pathology (01-08-2013)“…The low background incidence of tumors in rodents from subchronic toxicity studies makes it difficult to assess their relevance, especially when present only…”
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Unraveling the Pathogenesis of HIV Peripheral Neuropathy: Insights from a Simian Immunodeficiency Virus Macaque Model
Published in ILAR journal (01-01-2014)“…Peripheral neuropathy (PN) is the most frequent neurologic complication in individuals infected with human immunodeficiency virus (HIV). It affects over one…”
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Altered cutaneous nerve regeneration in a simian immunodeficiency virus / macaque intracutaneous axotomy model
Published in Journal of comparative neurology (1911) (20-05-2009)“…To characterize the regenerative pattern of cutaneous nerves in simian immunodeficiency virus (SIV)‐infected and uninfected macaques, excisional axotomies were…”
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Pathogenesis of Simian Immunodeficiency Virus-Induced Alterations in Macaque Trigeminal Ganglia
Published in Journal of neuropathology and experimental neurology (01-01-2007)“…Peripheral neuropathy is the most frequent neurologic complication associated with human immunodeficiency virus (HIV) infection, yet its pathogenesis remains…”
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From mice to macaques--animal models of HIV nervous system disease
Published in Current HIV research (01-07-2006)“…Lentiviral diseases of animals have been recognized for over a century, long before HIV was recognized as the cause of AIDS. All lentiviruses cause…”
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