Search Results - "Laakmann, Sandra"

Load-Reducing Therapy Prevents Development of Arrhythmogenic Right Ventricular Cardiomyopathy in Plakoglobin-Deficient Mice by Fabritz, Larissa, MD, Hoogendijk, Mark G., MD, Scicluna, Brendon P., MSc, van Amersfoorth, Shirley C.M., MSc, Fortmueller, Lisa, DVM, Wolf, Susanne, DVM, Laakmann, Sandra, DVM, Kreienkamp, Nina, Piccini, Ilaria, PhD, Breithardt, Günter, MD, Ruiz Noppinger, Patricia, PhD, Witt, Henning, PhD, Ebnet, Klaus, PhD, Wichter, Thomas, MD, Levkau, Bodo, MD, Franke, Werner W., PhD, Pieperhoff, Sebastian, PhD, de Bakker, Jacques M.T., PhD, Coronel, Ruben, MD, PhD, Kirchhof, Paulus, MD

“…Objectives We used a murine model of arrhythmogenic right ventricular cardiomyopathy (ARVC) to test whether reducing ventricular load prevents or slows…”
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PITX2c Is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene Expression by Kirchhof, Paulus, Kahr, Peter C, Kaese, Sven, Piccini, Ilaria, Vokshi, Ismail, Scheld, Hans-Heinrich, Rotering, Heinrich, Fortmueller, Lisa, Laakmann, Sandra, Verheule, Sander, Schotten, Ulrich, Fabritz, Larissa, Brown, Nigel A

“…BACKGROUND—Intergenic variations on chromosome 4q25, close to the PITX2 transcription factor gene, are associated with atrial fibrillation (AF). We therefore…”
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Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability by Blana, Andreas, MD, Kaese, Sven, BS, Fortmüller, Lisa, VetD, Laakmann, Sandra, VetD, Damke, Dierk, MD, van Bragt, Kelly, BS, Eckstein, Jens, MD, Piccini, Ilaria, PhD, Kirchhefer, Uwe, MD, Nattel, Stanley, MD, FHRS, Breithardt, Günter, MD, FHRS, Carmeliet, Peter, MD, Carmeliet, Edward, PhD, Schotten, Ulrich, MD, PhD, Verheule, Sander, PhD, Kirchhof, Paulus, MD, FHRS, Fabritz, Larissa, MD

“…Background Patients with long QT syndrome (LQTS) are at increased risk not only for ventricular arrhythmias but also for atrial pathology including atrial…”
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Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3 by Fabritz, Larissa, Damke, Dierk, Emmerich, Markus, Kaufmann, Susann G., Theis, Kathrin, Blana, Andreas, Fortmüller, Lisa, Laakmann, Sandra, Hermann, Sven, Aleynichenko, Elena, Steinfurt, Johannes, Volkery, Daniela, Riemann, Burkhard, Kirchhefer, Uwe, Franz, Michael R., Breithardt, Günter, Carmeliet, Edward, Schäfers, Michael, Maier, Sebastian K.G., Carmeliet, Peter, Kirchhof, Paulus

“…Aims Clinical observations in patients with long QT syndrome carrying sodium channel mutations (LQT3) suggest that bradycardia caused by parasympathetic…”
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Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice by Froese, Alexander, Breher, Stephanie S, Waldeyer, Christoph, Schindler, Roland F R, Nikolaev, Viacheslav O, Rinné, Susanne, Wischmeyer, Erhard, Schlueter, Jan, Becher, Jan, Simrick, Subreena, Vauti, Franz, Kuhtz, Juliane, Meister, Patrick, Kreissl, Sonja, Torlopp, Angela, Liebig, Sonja K, Laakmann, Sandra, Müller, Thomas D, Neumann, Joachim, Stieber, Juliane, Ludwig, Andreas, Maier, Sebastian K, Decher, Niels, Arnold, Hans-Henning, Kirchhof, Paulus, Fabritz, Larissa, Brand, Thomas

“…Cardiac pacemaker cells create rhythmic pulses that control heart rate; pacemaker dysfunction is a prevalent disorder in the elderly, but little is known about…”
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Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice by Kirchhof, Paulus, Marijon, Eloi, Fabritz, Larissa, Li, Na, Wang, Wei, Wang, Tiannan, Schulte, Kirsten, Hanstein, Juliane, Schulte, Jan S, Vogel, Mathis, Mougenot, Nathalie, Laakmann, Sandra, Fortmueller, Lisa, Eckstein, Jens, Verheule, Sander, Kaese, Sven, Staab, Ariane, Grote-Wessels, Stephanie, Schotten, Ulrich, Moubarak, Ghassan, Wehrens, Xander H.T, Schmitz, Wilhelm, Hatem, Stéphane, Müller, Frank Ulrich

“…Abstract Background and methods Atrial fibrillation (AF) is the most common cardiac arrhythmia in clinical practice. The substrate of AF is composed of a…”
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Regional, age-dependent, and genotype-dependent differences in ventricular action potential duration and activation time in 410 Langendorff-perfused mouse hearts by Waldeyer, Christoph, Fabritz, Larissa, Fortmueller, Lisa, Gerss, Joachim, Damke, Dierk, Blana, Andreas, Laakmann, Sandra, Kreienkamp, Nina, Volkery, Daniela, Breithardt, Günter, Kirchhof, Paulus

“…Although numerous studies have reported the effects of genetic alterations on murine electrophysiology, the range of normal values for ventricular activation,…”
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Corrigendum to “Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice” Int J Cardiol 166 (2013), 366–74 by Kirchhof, Paulus, Marijon, Eloi, Fabritz, Larissa, Li, Na, Wang, Wei, Wang, Tiannan, Schulte, Kirsten, Hanstein, Juliane, Schulte, Jan S, Vogel, Mathis, Mougenot, Nathalie, Laakmann, Sandra, Fortmueller, Lisa, Eckstein, Jens, Verheule, Sander, Kaese, Sven, Staab, Ariane, Grote-Wessels, Stephanie, Schotten, Ulrich, Moubarak, Ghassan, Wehrens, Xander H.T, Schmitz, Wilhelm, Hatem, Stéphane, Müller, Frank Ulrich

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VARIATIONS IN PITX2C EXPRESSION: ALTERING SUSCEPTIBILITY TO ATRIAL FIBRILLATION? by Kahr, Peter C, Vokshi, Ismail, Kaese, Sven, Piccini, Ilaria, Scheld, Hans-Heinrich, Rotering, Heinrich, Fortmueller, Lisa, Laakmann, Sandra, Verheule, Sander, Schotten, Ulrich, Fabritz, Larissa, Brown, Nigel A, Kirchhof, Paulus

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