Search Results - "LaVange, LM"

The role of nonrandomized trials in the evaluation of oncology drugs by Simon, R, Blumenthal, GM, Rothenberg, ML, Sommer, J, Roberts, SA, Armstrong, DK, LaVange, LM, Pazdur, R

“…Although randomized trials provide the most reliable evidence of a drug's safety and efficacy, there are situations where randomized trials are not possible or…”
Get full text

Master Protocols to Study Multiple Therapies, Multiple Diseases, or Both by Woodcock, Janet, LaVange, Lisa M

“…This review considers master protocols, which involve the study of one or more interventions in multiple diseases or of a single disease with multiple…”
Get full text

Aspirin Use and Respiratory Morbidity in COPD: A Propensity Score-Matched Analysis in Subpopulations and Intermediate Outcome Measures in COPD Study by Fawzy, Ashraf, Putcha, Nirupama, Aaron, Carrie P, Bowler, Russell P, Comellas, Alejandro P, Cooper, Christopher B, Dransfield, Mark T, Han, MeiLan K, Hoffman, Eric A, Kanner, Richard E, Krishnan, Jerry A, Labaki, Wassim W, Paine, 3rd, Robert, Paulin, Laura M, Peters, Stephen P, Wise, Robert, Barr, R Graham, Hansel, Nadia N

“…Aspirin use in COPD has been associated with reduced all-cause mortality in meta-regression analysis with few equivocal studies. However, the effect of aspirin…”
Get full text

Alignment of Inhaled Chronic Obstructive Pulmonary Disease Therapies with Published Strategies. Analysis of the Global Initiative for Chronic Obstructive Lung Disease Recommendations in SPIROMICS by Ghosh, Sohini, Anderson, Wayne H, Putcha, Nirupama, Han, Meilan K, Curtis, Jeffrey L, Criner, Gerard J, Dransfield, Mark T, Barr, R Graham, Krishnan, Jerry A, Lazarus, Stephen C, Cooper, Christopher B, Paine, 3rd, Robert, Peters, Stephen P, Hansel, Nadia N, Martinez, Fernando J, Drummond, M Bradley

“…Despite awareness of chronic obstructive pulmonary disease (COPD) treatment recommendations, uptake is poor. The Subpopulations and Intermediate Outcome…”
Get full text

Phase 2 Randomized Safety and Efficacy Trial of Nebulized Denufosol Tetrasodium in Cystic Fibrosis by Deterding, Robin R, LaVange, Lisa M, Engels, Jean M, Mathews, Dave W, Coquillette, Sarah J, Brody, Alan S, Millard, Steve P, Ramsey, Bonnie W, Cystic Fibrosis Therapeutics Development Network and Inspire 08-103 Working Group

“…Denufosol tetrasodium is a selective P2Y(2) agonist that enhances mucosal hydration and mucus clearance by activating Cl(-) secretion and inhibiting epithelial…”
Get full text

Double-Masked, Placebo-Controlled Safety and Efficacy Trial of Diquafosol Tetrasodium (INS365) Ophthalmic Solution for the Treatment of Dry Eye by Tauber, J, Davitt, W F, Bokosky, J E, Nichols, K K, Yerxa, B R, Schaberg, A E, LaVange, L M, Mills-Wilson, M C, Kellerman, D J

“…PURPOSE:To investigate the safety and efficacy of diquafosol tetrasodium, a P2Y2 receptor agonist that stimulates fluid and mucin secretion on the ocular…”
Get full text

Randomization-based nonparametric methods for the analysis of multicentre trials by LaVange, Lisa M, Durham, Todd A, Koch, Gary G

“…Multicentre trials offer several advantages over single centre trials in clinical research, including the ability to recruit patients at a faster rate over the…”
Get full text

Applying sample survey methods to clinical trials data by LaVange, L. M., Koch, G. G., Schwartz, T. A.

“…This paper outlines the utility of statistical methods for sample surveys in analysing clinical trials data. Sample survey statisticians face a variety of…”
Get full text

Statistical approaches to effectiveness measurement and outcome-driven re-randomizations in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) studies by Davis, Sonia M, Koch, Gary G, Davis, C E, LaVange, Lisa M

“…The design of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia and Alzheimer's disease studies pose several statistical…”
Get full text

Sertraline versus imipramine to prevent relapse in chronic depression by Koran, Lorrin M., Gelenberg, Alan J., Kornstein, Susan G., Howland, Robert H., Friedman, Richard A., DeBattista, Charles, Klein, Daniel, Kocsis, James H., Schatzberg, Alan F., Thase, Michael E., Rush, A.John, Hirschfeld, Robert M.A., LaVange, Lisa M., Keller, Martin B.

“…Background: Chronic depressions are common, disabling and under-treated, and long-term treatment is little studied. We report the continuation phase results…”
Get full text

Infant health and development program for low birth weight, premature infants : program elements, family participation, and child intelligence by RAMEY, C. T, BRYANT, D. ML, WASIK, B. H, SPARLING, J. J, FENDT, K. H, LAVANGE, L. M

“…The Infant Health and Development Program was an eight-site randomized controlled trial testing the efficacy of early intervention to enhance the cognitive,…”
Get full text

MSQ: Migraine-Specific Quality-of-Life Questionnaire. Further investigation of the factor structure by Jhingran, P, Davis, S M, LaVange, L M, Miller, D W, Helms, R W

“…MSQ, the 16-item Migraine-Specific Quality-of-Life Questionnaire (Version 1.0), was developed by Glaxo Wellcome Inc. to assess the effect of migraine and its…”
Get full text

Urinary cotinine and parent history (questionnaire) as indicators of passive smoking and predictors of lower respiratory illness in infants by Margolis, Peter A., Keyes, Lynette L., Greenberg, Robert A., Bauman, Karl E., LaVange, Lisa M.

“…Studies of the effects of passive smoking on lower respiratory illness (LRI) have relied on questionnaires to measure exposure. We studied the association…”
Get full text

Evaluation of a home-based intervention program to reduce infant passive smoking and lower respiratory illness by GREENBERG, R. A, STRECHER, V. J, GLOVER, L. H, HALEY, N. J, LODA, F. A, BAUMAN, K. E, BOAT, B. W, FOWLER, M. G, KEYES, L. L, DENNY, F. W, CHAPMAN, R. S, STEDMAN, H. C, LAVANGE, L. M

“…We conducted a randomized controlled trial to determine whether a home-based intervention program could reduce infant passive smoking and lower respiratory…”
Get full text

Application of sample survey methods for modelling ratios to incidence densities by Lavange, L M, Keyes, L L, Koch, G G, Margolis, P A

“…We describe ratio estimation methods for multivariately analysing incidence densities from prospective epidemiologic studies. Commonly used in survey data…”
Get more information

Lower respiratory illness in infants and low socioeconomic status by Margolis, P A, Greenberg, R A, Keyes, L L, LaVange, L M, Chapman, R S, Denny, F W, Bauman, K E, Boat, B W

“…Infants from families of low socioeconomic status are said to suffer higher rates of lower respiratory illness, but this assertion has not been carefully…”
Get full text

Quality control of oncology clinical trials by Meyerson, L J, Wiens, B L, LaVange, L M, Koutsoukos, A D

“…This article discusses issues that are essential to ensuring the reliability of the conclusions of oncology clinical trials. Though quality control is…”
Get more information

Double-blind Switch Study of Imipramine or Sertraline Treatment of Antidepressant-Resistant Chronic Depression by Thase, Michael E, Rush, A. John, Howland, Robert H, Kornstein, Susan G, Kocsis, James H, Gelenberg, Alan J, Schatzberg, Alan F, Koran, Lorrin M, Keller, Martin B, Russell, James M, Hirschfeld, Robert M. A, LaVange, Lisa M, Klein, Daniel N, Fawcett, Jan, Harrison, Wilma

“…BACKGROUND Although various strategies have been proposed to treat antidepressant nonresponders, little controlled research has been published that examines…”
Get full text