Search Results - "LaToya Jones"

Silicone oil induced aggregation of proteins by Jones, Latoya S, Kaufmann, Allyn, Middaugh, C Russell

“…Prior to delivery to the patient, protein pharmaceuticals often come in contact with a variety of surfaces (e.g., syringes and stoppers), which are treated to…”
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Effects of Adsorption to Aluminum Salt Adjuvants on the Structure and Stability of Model Protein Antigens by Jones, LaToya S., Peek, Laura J., Power, Jonathan, Markham, Aaron, Yazzie, Brian, Middaugh, C. Russell

“…The effect of adsorption onto aluminum salt adjuvants on the structure and stability of three model protein antigens was studied using fluorescence and Fourier…”
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Vaccines with aluminum-containing adjuvants: optimizing vaccine efficacy and thermal stability by Clapp, Tanya, Siebert, Paul, Chen, Dexiang, Jones Braun, LaToya

“…Aluminum-containing adjuvants have been used to enhance the immune response against killed, inactivated, and subunit antigens for more than seven decades…”
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Polyanions and the Proteome by Jones, LaToya S, Yazzie, Brian, Middaugh, C Russell

“…The behavior of the proteome reflects spatial and temporal organization both within and without cells. We propose that various macromolecular entities…”
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Tribute to Evan Weissman on behalf of the Syracuse-Onondaga Food Systems Alliance by Ackerman, Maura, Carney, Mary, Colebrook, Brandy, Gaudé, Nel, Johnson, Elissa, Jones, LaToya, Knapp, David, Lyons, Jessi, Ricardo, Peter, Robinson, Jonnell, Viens, Rachel, Waterman, Curtis

“…An obituary for Ewan Weissman, professor at the Syracuse University, is presented. Weissman was a driving force behind the formation of the Syracuse-Onondaga…”
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Thermal stability of vaccines by Brandau, Duane T, Jones, Latoya S, Wiethoff, Christopher M, Rexroad, Jason, Middaugh, C Russell

“…Worldwide vaccination programs against infectious diseases and toxins are estimated to save approximately 3 million lives yearly. Tragically, however, another…”
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A systematic approach to stabilizing EBA-175 RII-NG for use as a malaria vaccine by Peek, Laura J., Brandau, Duane T., Jones, LaToya S., Joshi, Sangeeta B., Middaugh, C. Russell

“…Region II of the erythrocyte-binding antigen (EBA-175 RII) has been identified as a promising target for a malaria vaccine. A systematic approach to identify…”
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Secondary structures of proteins adsorbed onto aluminum hydroxide: Infrared spectroscopic analysis of proteins from low solution concentrations by Dong, Aichun, Jones, LaToya S., Kerwin, Bruce A., Krishnan, Sampath, Carpenter, John F.

“…Comparative studies of the secondary structures of six model proteins, adsorbed onto aluminum hydroxide gel (Alhydrogel) or in aqueous solution, were carried…”
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Effects of sucrose on conformational equilibria and fluctuations within the native‐state ensemble of proteins by Kim, Yong‐Sung, Jones, Latoya S., Dong, Aichun, Kendrick, Brent S., Chang, Byeong S., Manning, Mark C., Randolph, Theodore W., Carpenter, John F.

“…Osmolytes increase the thermodynamic conformational stability of proteins, shifting the equilibrium between native and denatured states to favor the native…”
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Characterization of the freeze sensitivity of a hepatitis B vaccine by Chen, Dexiang, Tyagi, Anil, Carpenter, John, Perkins, Shalimar, Sylvester, David, Guy, Mark, Kristensen, Debra D., Jones Braun, LaToya

“…Recent studies have revealed that vaccines containing aluminum adjuvant are exposed to sub-zero temperatures while in the cold chain more frequently than was…”
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Surfactant-protein interactions by Randolph, Theodore W, Jones, LaToya S

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A heat-stable hepatitis B vaccine formulation by Jezek, Jan, Chen, Dexiang, Watson, Lynne, Crawford, Jill, Perkins, Shalimar, Tyagi, Anil, Jones Braun, LaToya

“…The purpose of the present study was to develop a formulation of recombinant hepatitis B vaccine with improved stability at elevated temperatures. A validated,…”
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Mechanism for benzyl alcohol-induced aggregation of recombinant human interleukin-1 receptor antagonist in aqueous solution by Zhang, Ye, Roy, Shouvik, Jones, Latoya S, Krishnan, Sampathkumar, Kerwin, Bruce A, Chang, Byeong S, Manning, Mark C, Randolph, Theodore W, Carpenter, John F

“…Benzyl alcohol, an antimicrobial preservative, accelerates aggregation and precipitation of recombinant human interleukin-1 receptor antagonist (rhIL-1ra) in…”
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The role of adjuvant in mediating antigen structure and stability by Braun, Latoya Jones, Eldridge, Aimee M, Cummiskey, Jessica, Arthur, Kelly K, Wuttke, Deborah S

“…The purpose of this study was to probe the fate of a model antigen, a cysteine-free mutant of bacteriophage T4 lysozyme, to the level of fine structural…”
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The effects of Tween 20 and sucrose on the stability of anti-L-selectin during lyophilization and reconstitution by Jones, L S, Randolph, T W, Kohnert, U, Papadimitriou, A, Winter, G, Hagmann, M L, Manning, M C, Carpenter, J F

“…We have chosen an anti-L-selectin antibody as a model protein to investigate the effects of sucrose and/or Tween 20 on protein stability during lyophilization…”
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Effect of Tween 20 on freeze-thawing- and agitation-induced aggregation of recombinant human factor XIII by Kreilgaard, L, Jones, L S, Randolph, T W, Frokjaer, S, Flink, J M, Manning, M C, Carpenter, J F

“…Agitation- and freeze-thawing-induced aggregation of recombinant human factor XIII (rFXIII) is due to interfacial adsorption and denaturation at the air-liquid…”
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Effect of zinc binding and precipitation on structures of recombinant human growth hormone and nerve growth factor by Yang, T H, Cleland, J L, Lam, X, Meyer, J D, Jones, L S, Randolph, T W, Manning, M C, Carpenter, J F

“…Metal-induced precipitation of protein therapeutics is being used and further developed as a processing step in protein formulation and may have utility in…”
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Freezing-induced perturbation of tertiary structure of a monoclonal antibody by Liu, Lu, Braun, Latoya Jones, Wang, Wei, Randolph, Theodore W, Carpenter, John F

“…We studied the effects of pH and solution additives on freezing-induced perturbations in the tertiary structure of a monoclonal antibody (mAb) by intrinsic…”
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Freeze-thaw stress of Alhydrogel® alone is sufficient to reduce the immunogenicity of a recombinant hepatitis B vaccine containing native antigen by Clapp, Tanya, Munks, Michael W, Trivedi, Ruchit, Kompella, Uday B, Braun, LaToya Jones

“…Highlights • We examined the effects on the immunogenicity of a vaccine containing freeze-thaw stressed Alhydrogel® with non-stressed antigen. • Protecting a…”
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An Examination of Elementary Teachers' Reasons for Leaving the Teaching Profession With Traditional and Alternative Certifications in South Carolina by Curry-Jones, LaToya S

“…This research study will examine elementary school level traditionally and alternatively certified teachers who leave the teaching profession. The sole focus…”
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