Search Results - "LaRosée, Paul"
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1
The soluble transferrin receptor reflects tumor load in chronic lymphocytic leukemia
Published in Clinical chemistry and laboratory medicine (01-10-2007)“…The soluble transferrin receptor (sTfR) is a parameter of erythropoietic activity and iron deficiency. Increased levels have also been described in…”
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2
Regulation of protein kinase C isozymes in volume overload cardiac hypertrophy
Published in Molecular and cellular biochemistry (01-07-2004)“…Protein kinase C (PKC) is a family of at least 11 isozymes and known to play a crucial role in myocardial growth. The present study was performed to…”
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3
Tyrosinekinase inhibition facilitates cooperation of transcription factor SALL4 and ABC transporter A3 towards intrinsic CML cell drug resistance
Published in British journal of haematology (01-04-2013)“…Summary Although BCR‐ABL1 tyrosine kinase inhibitors reliably induce disease remission for patients with chronic myeloid leukaemia (CML), unlimited extension…”
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4
Differential regulation of cardiac protein kinase C isozyme expression after aortic banding in rat
Published in Cardiovascular research (01-10-2002)“…Protein kinase C (PKC) plays a key role in myocardial hypertrophy. To evaluate whether its isoforms are expressed differentially during gradual development of…”
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5
Positron Emission Tomography (PET) Guided Therapy of Aggressive Lymphomas – a Randomized Controlled Trial Comparing Different Treatment Approaches Based on Interim PET Results (PETAL Trial)
Published in Blood (06-12-2014)“…Introduction: The predictive value of 18-fluorodeoxyglucose PET performed after a few cycles of chemotherapy has been questioned in aggressive lymphomas…”
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6
Desensitization of the pulmonary adenylyl cyclase system : A cause of airway hyperresponsiveness in congestive heart failure?
Published in Journal of the American College of Cardiology (01-09-1999)“…This study was designed to investigate whether the adrenergic signal transduction in the lung and the responsiveness of airway smooth muscle to adrenergic…”
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7
Temsirolimus in Combination with Bendamustine and Rituximab (BeRT) for the Treatment of Relapsed Mantle Cell and Follicular Lymphoma: Final Phase I/II Results
Published in Blood (02-12-2016)“…Background: mTOR inhibition has been shown to be effective in various subtypes of malignant lymphomas (Smith et al, JCO 2010). Furthermore, in relapsed MCL a…”
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8
Temsirolimus in Combination with Bendamustine and Rituximab for the Treatment of Relapsed Mantle Cell and Follicular Lymphoma: Report on an Ongoing Phase I/II Trial
Published in Blood (03-12-2015)“…Background: mTOR inhibition has been shown to be effective in various subtypes of malignant lymphomas. In relapsed MCL a phase III trial could prove…”
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9
Safety and Clinical Activity of Temsirolimus in Combination with Rituximab and DHAP in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma - Report of the Prospective, Multicenter Phase II STORM Trial
Published in Blood (02-12-2016)“…Purpose. To evaluate the safety, tolerability and efficacy of the combination of the mTOR inhibitor Temsirolimus and a standard salvage regimen (R-DHAP) in…”
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10
Tyrosinekinase inhibition facilitates cooperation of transcription factor SALL 4 and ABC transporter A3 towards intrinsic CML cell drug resistance
Published in British journal of haematology (01-04-2013)“…Although BCR ‐ ABL 1 tyrosine kinase inhibitors reliably induce disease remission for patients with chronic myeloid leukaemia ( CML ), unlimited extension of…”
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11
Desensitization of the pulmonary adenylyl cyclase system
Published in Journal of the American College of Cardiology (01-09-1999)“…OBJECTIVES This study was designed to investigate whether the adrenergic signal transduction in the lung and the responsiveness of airway smooth muscle to…”
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