Search Results - "LaPointe, L L"
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Combined ursodeoxycholic acid (UDCA) and fenofibrate in primary biliary cholangitis patients with incomplete UDCA response may improve outcomes
Published in Alimentary pharmacology & therapeutics (01-01-2016)“…Summary Background Fibrates appear to improve biochemistry in patients with primary biliary cholangitis (PBC), but it is unclear which factors predict response…”
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A single-cell RNA-seq analysis unravels the heterogeneity of primary cultured human corneal endothelial cells
Published in Scientific reports (08-06-2023)“…The cornea is a transparent and avascular tissue located in front of the eye. Its inner surface is lined by a monolayer of corneal endothelial cells (CECs),…”
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Single cell transcriptomics reveals the heterogeneity of the human cornea to identify novel markers of the limbus and stroma
Published in Scientific reports (05-11-2021)“…The cornea is the clear window that lets light into the eye. It is composed of five layers: epithelium, Bowman’s layer, stroma, Descemet’s membrane and…”
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Sclerenchymatous ring as a barrier to phloem feeding by Asian citrus psyllid: Evidence from electrical penetration graph and visualization of stylet pathways
Published in PloS one (09-03-2017)“…Asian citrus psyllid (Diaphorina citri) feeding behaviors play a significant role in the transmission of the phloem-limited Candidatus Liberibacter asiaticus…”
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Computational evidence for multi-layer crosstalk between the cadherin-11 and PDGFR pathways
Published in Scientific reports (22-09-2023)“…Various cell surface receptors play an important role in the differentiation and self-renewal of human mesenchymal stem cells (hMSCs). One example of such…”
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Force-dependent focal adhesion assembly and disassembly: A computational study
Published in PLoS computational biology (06-10-2023)“…Cells interact with the extracellular matrix (ECM) via cell–ECM adhesions. These physical interactions are transduced into biochemical signals inside the cell…”
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Oxygen and nutrient delivery in tissue engineering: Approaches to graft vascularization
Published in Journal of tissue engineering and regenerative medicine (01-10-2019)“…The field of tissue engineering is making great strides in developing replacement tissue grafts for clinical use, marked by the rapid development of novel…”
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Overcoming kidney organoid challenges for regenerative medicine
Published in npj Regenerative medicine (30-04-2020)“…Kidney organoids derived from human induced pluripotent stem cells bear the potential to be used as a regenerative medicine renal replacement therapy. Advances…”
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The response of three-dimensional pancreatic alpha and beta cell co-cultures to oxidative stress
Published in PloS one (15-03-2022)“…The pancreatic islets of Langerhans have low endogenous antioxidant levels and are thus especially sensitive to oxidative stress, which is known to influence…”
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10
Machine Learning for Characterization of Insect Vector Feeding
Published in PLoS computational biology (01-11-2016)“…Insects that feed by ingesting plant and animal fluids cause devastating damage to humans, livestock, and agriculture worldwide, primarily by transmitting…”
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The protein tyrosine phosphatase DEP-1/PTPRJ promotes breast cancer cell invasion and metastasis
Published in Oncogene (29-10-2015)“…DEP-1/PTPRJ is a receptor-like protein tyrosine phosphatase mainly known for its antiproliferative and tumor-suppressive functions. Many identified substrates…”
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Olfactory Cues Are Subordinate to Visual Stimuli in a Neotropical Generalist Weevil
Published in PloS one (16-01-2013)“…The tropical root weevil Diaprepes abbreviatus is a major pest of multiple crops in the Caribbean Islands and has become a serious constraint to citrus…”
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Diet improvement for western corn rootworm (Coleoptera: Chrysomelidae) larvae
Published in PloS one (17-11-2017)“…The western corn rootworm (WCR), Diabrotica virgifera virgifera LeConte, is the most serious insect pest of corn (Zea mays L.) in the United States and parts…”
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Sticking together: Harnessing cadherin biology for tissue engineering
Published in Acta biomaterialia (15-10-2021)“…[Display omitted] Directing cell behavior and building a tissue for therapeutic impact is the main goal of regenerative medicine, for which scientists need to…”
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Soft, Dynamic Hydrogel Confinement Improves Kidney Organoid Lumen Morphology and Reduces Epithelial–Mesenchymal Transition in Culture
Published in Advanced science (01-07-2022)“…Pluripotent stem cell‐derived kidney organoids offer a promising solution to renal failure, yet current organoid protocols often lead to off‐target cells and…”
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The Fungus Raffaelea lauricola Modifies Behavior of Its Symbiont and Vector, the Redbay Ambrosia Beetle (Xyleborus Glabratus), by Altering Host Plant Volatile Production
Published in Journal of chemical ecology (01-05-2017)“…The redbay ambrosia beetle Xyleborus glabratus is the vector of the symbiotic fungus, Raffaelea lauricola that causes laurel wilt, a highly lethal disease to…”
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Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencing
Published in npj Regenerative medicine (11-08-2021)“…The kidney is among the most complex organs in terms of the variety of cell types. The cellular complexity of human kidneys is not fully unraveled and this…”
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Changes in cognitive load and effects on parameters of gait
Published in Cogent psychology (31-12-2017)“…Reading or texting with a mobile phone while walking requires cognitive resource allocation and consequently induces changes in gait. Fifty-six young adults…”
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The Influence of Oropalatal Dimensions on the Measurement of Tongue Strength
Published in Dysphagia (01-12-2017)“…Tongue strength is routinely evaluated in clinical swallowing evaluations since lingual weakness is an established contributor to dysphagia. Tongue strength…”
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Fertilization stimulates root production in cloudberry rhizomes transplanted in a cutover peatland
Published in Canadian journal of plant science (01-12-2017)“…Cloudberry has good economic potential for Canada, but crop practices must be improved before commercial production can be established. Transplants usually…”
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