Search Results - "LaNoue, K.F."

Mitochondrial transport proteins of the brain by Berkich, D.A., Ola, M.S., Cole, J., Sweatt, A.J., Hutson, S.M., LaNoue, K.F.

“…In this study, cellular distribution and activity of glutamate and γ‐aminobutyric acid (GABA) transport as well as oxoglutarate transport across brain…”
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Regulation of plasma membrane permeability to calcium in primary cultures of rat hepatocytes by Zhang, Y, Duszynski, J, Hreniuk, S, Waybill, M M, LaNoue, K F

“…Experiments were designed to characterize the hormone sensitive transport of Ca2+ from the external media into rat hepatocytes maintained in culture. In the…”
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A multistep validation process of biomarkers for preclinical drug development by Freeman, W M, Bixler, G V, Brucklacher, R M, Lin, C-M, Patel, K M, VanGuilder, H D, LaNoue, K F, Kimball, S R, Barber, A J, Antonetti, D A, Gardner, T W, Bronson, S K

“…Biomarkers that can be measured in preclinical models in a high-throughput, reproducible manner offer the potential to increase the speed and efficacy of drug…”
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Tissue-specific effects of in vivo adenosine receptor blockade on glucose uptake in Zucker rats by Crist, G.H. (The Pennsylvania State University College of Medicine, Hershey, PA.), Xu, B.Y, LaNoue, K.F, Lang, C.H

“…Previous studies have shown that treatment of obese Zucker rats with the adenosine receptor antagonist 1,3‐dipropyl‐8‐(p‐acrylic) phenyl xanthine (BWA1433)…”
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Kinetic analysis of dynamic 13C NMR spectra: metabolic flux, regulation, and compartmentation in hearts by Yu, X., White, L.T., Doumen, C., Damico, L.A., LaNoue, K.F., Alpert, N.M., Lewandowski, E.D.

“…Control of oxidative metabolism was studied using 13C NMR spectroscopy to detect rate-limiting steps in 13C labeling of glutamate. 13C NMR spectra were…”
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A1 adenosine receptor antagonism improves glucose tolerance in Zucker rats by Xu, B, Berkich, D.A, Crist, G.H, LaNoue, K.F

“…The A1 adenosine receptor (A1ar) antagonist 1,3-dipropyl-8-(p-acrylic)-phenylxanthine (BW-1433) was administered to lean and obese Zucker rats to probe the…”
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Hormone-regulated Ca 2+ channel in rat hepatocytes revealed by whole cell patch clamp by Duszynski, J., Elensky, M., Cheung, J.Y., Tillotson, D.L., LaNoue, K.F.

“…An inward current responsible for hormone regulated Ca 2+ entry has been identified in cultured rat hepatocytes using whole cell patch clamp. Addition of 20 nM…”
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A sup 31 P NMR study of mitochondrial inorganic phosphate visibility: Effects of Ca sup 2+ , Mn sup 2+ , and the pH gradient by Hutson, S.M., Williams, G.D., Berkich, D.A., LaNoue, K.F., Briggs, R.W.

“…The effects of external pH, temperature, and Ca{sup 2+} and Mn{sup 2+} concentrations on the compartmentation and NMR visibility of inorganic phosphate (P{sub…”
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Attenuated adenosine-sensitivity and decreased adenosine-receptor number in adipocyte plasma membranes in human obesity by Kaartinen, J.M, Hreniuk, S.P, Martin, L.F, Ranta, S, LaNoue, K.F, Ohisalo, J.J

“…Fat-cells were isolated from patients of body-mass indices (BMIs) ranging from 17.9 to 83.9 kg/m2. Isoprenaline-stimulated cyclic AMP accumulation in cells…”
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Hormone-regulated Ca2+ channel in rat hepatocytes revealed by whole cell patch clamp by Duszynski, J, Elensky, M, Cheung, J Y, Tillotson, D L, LaNoue, K F

“…An inward current responsible for hormone regulated Ca2+ entry has been identified in cultured rat hepatocytes using whole cell patch clamp. Addition of 20 nM…”
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sup 31 P NMR saturation-transfer study of the in situ kinetics of the mitochondrial adenine nucleotide translocase by Masiakos, P.T., Williams, G.D., Berkich, D.A., Smith, M.B., LaNoue, K.F.

“…The exchange of intramitochondrial ATP (ATP{sub in}) for extramitochondrial ATP (ATP{sub out}) was measured by using {sup 31}P NMR spectroscopy over a range of…”
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A1-adenosine receptor-mediated inhibition of adipocyte adenylate cyclase and lipolysis in Zucker rats by Vannucci, S.J. (The Pennsylvania State University, Hershey, PA), Klim, C.M, Martin, L.F, LaNoue, K.F

“…Hormone-stimulated lipolysis is reduced in genetically obese rodents and may contribute to the increased adiposity characteristic of the obese state…”
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β-Adrenergic responsiveness of adenylate cyclase in human adipocyte plasma membranes in obesity and after massive weight reduction by Kaartinen, Johanna M., LaNoue, Kathryn F., Martin, Louis F., Vikman, Hanna-Leena, Ohisalo, Jorma J.

“…The aim of this study was to find out how β-adrenergic responsiveness of adipocytes is altered in obesity and by weight loss and to investigate what mechanisms…”
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Rates of various reactions catalyzed by ATP synthase as related to the mechanism of ATP synthesis by Berkich, D A, Williams, G D, Masiakos, P T, Smith, M B, Boyer, P D, LaNoue, K F

“…The forward and reverse rates of the overall reaction catalyzed by the ATP synthase in intact rat heart mitochondria, as measured with 32P, were compared with…”
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The role of microcompartmentation in the regulation of glutamate metabolism by rat kidney mitochondria by Schoolwerth, A C, LaNoue, K F

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Glutamate dehydrogenase activation and ammonia formation by rat kidney mitochondria by Schoolwerth, A C, Nazar, B L, LaNoue, K F

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Phosphorus-31 NMR visibility and characterization of rat liver mitochondrial matrix adenine nucleotides by Hutson, Susan M, Berkich, Deborah, Williams, Gerald D, LaNoue, Kathryn F, Briggs, Richard W

“…Compartmentation and NMR visibility of mitochondrial adenine nucleotides were quantitated in isolated rat liver mitochondria respiring on succinate and…”
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