Search Results - "LaMarche, Nelson M."

Cutting edge: STAT6 signaling in eosinophils is necessary for development of allergic airway inflammation by Stokes, Kindra, LaMarche, Nelson M, Islam, Nasif, Wood, Amie, Huang, Weishan, August, Avery

“…Eosinophils are critical cellular mediators in allergic asthma and inflammation; however, the signals that regulate their functions are unclear. The…”
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Longitudinal analysis of invariant natural killer T cell activation reveals a cMAF-associated transcriptional state of NKT10 cells by Kane, Harry, LaMarche, Nelson M, Ní Scannail, Áine, Garza, Amanda E, Koay, Hui-Fern, Azad, Adiba I, Kunkemoeller, Britta, Stevens, Brenneth, Brenner, Michael B, Lynch, Lydia

“…Innate T cells, including CD1d-restricted invariant natural killer T (iNKT) cells, are characterized by their rapid activation in response to non-peptide…”
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Distinct iNKT Cell Populations Use IFNγ or ER Stress-Induced IL-10 to Control Adipose Tissue Homeostasis by LaMarche, Nelson M., Kane, Harry, Kohlgruber, Ayano C., Dong, Han, Lynch, Lydia, Brenner, Michael B.

“…Adipose tissue invariant natural killer T (iNKT) cells are phenotypically different from other iNKT cells because they produce IL-10 and control metabolic…”
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Adipose tissue at the nexus of systemic and cellular immunometabolism by Kohlgruber, Ayano C, LaMarche, Nelson M, Lynch, Lydia

“…Highlights • Immunometabolism can be split into two main themes: whole-body metabolism and cellular bioenergetics. • Adipose tissue is a prime example to…”
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TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer by Park, Matthew D., Reyes-Torres, Ivan, LeBerichel, Jessica, Hamon, Pauline, LaMarche, Nelson M., Hegde, Samarth, Belabed, Meriem, Troncoso, Leanna, Grout, John A., Magen, Assaf, Humblin, Etienne, Nair, Achuth, Molgora, Martina, Hou, Jinchao, Newman, Jenna H., Farkas, Adam M., Leader, Andrew M., Dawson, Travis, D’Souza, Darwin, Hamel, Steven, Sanchez-Paulete, Alfonso Rodriguez, Maier, Barbara, Bhardwaj, Nina, Martin, Jerome C., Kamphorst, Alice O., Kenigsberg, Ephraim, Casanova-Acebes, Maria, Horowitz, Amir, Brown, Brian D., De Andrade, Lucas Ferrari, Colonna, Marco, Marron, Thomas U., Merad, Miriam

“…Natural killer (NK) cells are commonly reduced in human tumors, enabling many to evade surveillance. Here, we sought to identify cues that alter NK cell…”
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Innate T Cells Govern Adipose Tissue Biology by LaMarche, Nelson M, Kohlgruber, Ayano C, Brenner, Michael B

“…During the past 25 y, the immune system has appeared as a key regulator of adipose tissue biology and metabolic homeostasis. In lean animals, adipose-resident…”
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Maternal infection programmes offspring immunity by LaMarche, Nelson M., Faith, Jeremiah J.

“…A preprint by Lim et al. looks at the effects of maternal infection on long-term immunity in offspring, showing that maternal IL-6-induced signalling in mice…”
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Adipose Dendritic Cells Come Out of Hiding by LaMarche, Nelson M., Lynch, Lydia

“…In this issue of Cell Metabolism, Macdougall et al. (2018) identify two subsets of conventional dendritic cells in visceral adipose tissue and demonstrate that…”
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An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis by LaMarche, Nelson M., Hegde, Samarth, Park, Matthew D., Maier, Barbara B., Troncoso, Leanna, Le Berichel, Jessica, Hamon, Pauline, Belabed, Meriem, Mattiuz, Raphaël, Hennequin, Clotilde, Chin, Theodore, Reid, Amanda M., Reyes-Torres, Iván, Nemeth, Erika, Zhang, Ruiyuan, Olson, Oakley C., Doroshow, Deborah B., Rohs, Nicholas C., Gomez, Jorge E., Veluswamy, Rajwanth, Hall, Nicole, Venturini, Nicholas, Ginhoux, Florent, Liu, Zhaoyuan, Buckup, Mark, Figueiredo, Igor, Roudko, Vladimir, Miyake, Kensuke, Karasuyama, Hajime, Gonzalez-Kozlova, Edgar, Gnjatic, Sacha, Passegué, Emmanuelle, Kim-Schulze, Seunghee, Brown, Brian D., Hirsch, Fred R., Kim, Brian S., Marron, Thomas U., Merad, Miriam

“…Myeloid cells are known to suppress antitumour immunity 1 . However, the molecular drivers of immunosuppressive myeloid cell states are not well defined. Here…”
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Activation strategies for invariant natural killer T cells by Kohlgruber, Ayano C., Donado, Carlos A., LaMarche, Nelson M., Brenner, Michael B., Brennan, Patrick J.

“…Invariant natural killer T (iNKT) cells are a specialized T cell subset that plays an important role in host defense, orchestrating both innate and adaptive…”
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Hematopoietic aging promotes cancer by fueling IL-1⍺-driven emergency myelopoiesis by Park, Matthew D, Le Berichel, Jessica, Hamon, Pauline, Wilk, C Matthias, Belabed, Meriem, Yatim, Nader, Saffon, Alexis, Boumelha, Jesse, Falcomatà, Chiara, Tepper, Alexander, Hegde, Samarth, Mattiuz, Raphaël, Soong, Brian Y, LaMarche, Nelson M, Rentzeperis, Frederika, Troncoso, Leanna, Halasz, Laszlo, Hennequin, Clotilde, Chin, Theodore, Chen, Earnest P, Reid, Amanda M, Su, Matthew, Cahn, Ashley Reid, Koekkoek, Laura L, Venturini, Nicholas, Wood-Isenberg, Shira, D'souza, Darwin, Chen, Rachel, Dawson, Travis, Nie, Kai, Chen, Zhihong, Kim-Schulze, Seunghee, Casanova-Acebes, Maria, Swirski, Filip K, Downward, Julian, Vabret, Nicolas, Brown, Brian D, Marron, Thomas U, Merad, Miriam

“…Age is a major risk factor for cancer, but how aging impacts tumor control remains unclear. Here, we establish that aging of the immune system, regardless of…”
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Transnuclear mice reveal Peyer's patch iNKT cells that regulate B‐cell class switching to IgG1 by Clancy‐Thompson, Eleanor, Chen, Gui Zhen, LaMarche, Nelson M, Ali, Lestat R, Jeong, Hee‐Jin, Crowley, Stephanie J, Boelaars, Kelly, Brenner, Michael B, Lynch, Lydia, Dougan, Stephanie K

“…Tissue‐resident iNKT cells maintain tissue homeostasis and peripheral surveillance against pathogens; however, studying these cells is challenging due to their…”
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Transnuclear mice reveal Peyer's patch iNKT cells that regulate B-cell class switching to IgG1 by Clancy-Thompson, Eleanor, Chen, Gui Zhen, LaMarche, Nelson M, Ali, Lestat R, Jeong, Hee-Jin, Crowley, Stephanie J, Boelaars, Kelly, Brenner, Michael B, Lynch, Lydia, Dougan, Stephanie K

“…Tissue-resident iNKT cells maintain tissue homeostasis and peripheral surveillance against pathogens; however, studying these cells is challenging due to their…”
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Author Correction: γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis by Kohlgruber, Ayano C., Gal-Oz, Shani T., LaMarche, Nelson M., Shimazaki, Moto, Duquette, Danielle, Koay, Hui-Fern, Nguyen, Hung N., Mina, Amir I., Paras, Tyler, Tavakkoli, Ali, von Andrian, Ulrich, Uldrich, Adam P., Godfrey, Dale I., Banks, Alexander S., Shay, Tal, Brenner, Michael B., Lynch, Lydia

“…In the version of this article initially published, three authors (Hui-Fern Kuoy, Adam P. Uldrich and Dale. I. Godfrey) and their affiliations, acknowledgments…”
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γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis by Kohlgruber, Ayano C., Gal-Oz, Shani T., LaMarche, Nelson M., Shimazaki, Moto, Duquette, Danielle, Koay, Hui-Fern, Nguyen, Hung N., Mina, Amir I., Paras, Tyler, Tavakkoli, Ali, von Andrian, Ulrich, Uldrich, Adam P., Godfrey, Dale I., Banks, Alexander S., Shay, Tal, Brenner, Michael B., Lynch, Lydia

“…γδ T cells are situated at barrier sites and guard the body from infection and damage. However, little is known about their roles outside of host defense in…”
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Author Correction: [gamma][delta] T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis by Kohlgruber, Ayano C, Gal-Oz, Shani T, LaMarche, Nelson M, Shimazaki, Moto, Duquette, Danielle, Koay, Hui-Fern, Nguyen, Hung N

“…In the version of this article initially published, three authors (Hui-Fern Kuoy, Adam P. Uldrich and Dale. I. Godfrey) and their affiliations, acknowledgments…”
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Hematopoietic aging promotes cancer by fueling IL-1α-driven emergency myelopoiesis by Park, Matthew D., Berichel, Jessica Le, Hamon, Pauline, Wilk, C. Matthias, Belabed, Meriem, Yatim, Nader, Saffon, Alexis, Boumelha, Jesse, Falcomatà, Chiara, Tepper, Alexander, Hegde, Samarth, Mattiuz, Raphaël, Soong, Brian Y., LaMarche, Nelson M., Rentzeperis, Frederika, Troncoso, Leanna, Halasz, Laszlo, Hennequin, Clotilde, Chin, Theodore, Chen, Earnest P., Reid, Amanda M., Su, Matthew, Cahn, Ashley Reid, Koekkoek, Laura L., Venturini, Nicholas, Wood-isenberg, Shira, D’souza, Darwin, Chen, Rachel, Dawson, Travis, Nie, Kai, Chen, Zhihong, Kim-Schulze, Seunghee, Casanova-Acebes, Maria, Swirski, Filip K., Downward, Julian, Vabret, Nicolas, Brown, Brian D., Marron, Thomas U., Merad, Miriam

“…Age is a major risk factor for cancer, but how aging impacts tumor control remains unclear. Here, we establish that aging of the immune system, regardless of…”
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[delta] T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis by Kohlgruber, Ayano C, Gal-Oz, Shani T, LaMarche, Nelson M, Shimazaki, Moto, Duquette, Danielle, Nguyen, Hung N, Mina, Amir I

“…[gamma][delta] T cells are situated at barrier sites and guard the body from infection and damage. However, little is known about their roles outside of host…”
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Abstract CT199: Rescuing response to ICI by blocking the type-2 immune axis in patients with NSCLC progressing on immunotherapy: A phase 1b/2 trial of dupilumab administered with checkpoint blockade by Marron, Thomas Urban, LaMarche, Nelson M., Park, Matthew D., Hegde, Samarth, Fitzgerald, Bailey, Hennequin, Clotilde, Mattiuz, Raphael, Belabed, Meriem, Berichel, Jessica Le, Maier, Barbara, Hall, Nicole, Miller, Justin, Doroshow, Deborah B., Rohs, Nicholas, Veluswamy, Rajwanth, Venturini, Nicholas, Gomez, Jorge E., Rolfo, Christian, Yankelevitz, David, Chaddha, Udit, Harkin, Timothy, Beasley, Mary B., Kim-schulze, Seunghee, Gnjatic, Sacha, Hirsch, Fred R., Merad, Miriam

“…Abstract Type-2 cytokines are hypothesized to promote an immune-permissive milieu for cancer to grow. Through scRNAseq and CITEseq on human non-small cell lung…”
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