Search Results - "LaJeunesse, D"

Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs by Martel-Pelletier, J, Lajeunesse, D, Reboul, P, Pelletier, J-P

“…Dual 5-LOX/COX inhibitors are potential new drugs to treat inflammation. They act by blocking the formation of both prostaglandins and leucotrienes but do not…”
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Elevated hepatocyte growth factor levels in osteoarthritis osteoblasts contribute to their altered response to bone morphogenetic protein-2 and reduced mineralization capacity by Abed, E, Bouvard, B, Martineau, X, Jouzeau, J.-Y, Reboul, P, Lajeunesse, D

“…Abstract Purpose Clinical and in vitro studies suggest that subchondral bone sclerosis due to abnormal osteoblasts is involved in the progression of…”
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I-12 ROLE OF BONE IN THE DEVELOPMENT AND PROGRESSION OF OSTEOARTHRITIS by Lajeunesse, D

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Carboxylated and uncarboxylated osteocalcin levels are not linked with insulin resistance in osteoarthritis patients by Abed, É, Martel-Pelletier, J, Pelletier, J.-P, Mineau, F, Delorme, P, Lajeunesse, D

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DOES SUBCHONDRAL BONE TISSUE REMODELING OR CELL FUNCTION PLAY A ROLE IN ARTICULAR CARTILAGE LOSS IN OSTEOARTHRITIS? by Lajeunesse, D

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Alterations of the non-canonical Wnt/PKC pathway in human osteoarthritis osteoblasts by Abed, É, Siwing, V, Martineau, X, Delalandre, A, Lajeunesse, D

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Targeting the Atypical Chemokine Receptor ACKR3/CXCR7: Phase 1 - Phage Display Peptide Identification and Characterization by Vestal, R D, LaJeunesse, D R, Taylor, E W

“…One of the greatest challenges in fighting cancer is cell targeting and biomarker selection. The Atypical Chemokine Receptor ACKR3/CXCR7 is expressed on many…”
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Resveratrol Regulates the Wnt/ß-catenin pathway in human osteoarthritis osteoblasts by Abed, É, Delalandre, A, Pelletier, J.-P, Martel-Pelletier, J, Lajeunesse, D

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Elevated endogenous sclerostin levels in osteoarthritis subchondral osteoblasts contribute to reduced Wnt/B-catenin signaling in these cells by Abed, E, Delalandre, A, Couchourel, D, Lajeunesse, D

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Elevated hepatocyte growth factor levels in osteoarthritis osteoblasts contribute to their altered response to bone morphogenetic protein-2 and reduced mineralization by Abed, É, Bouvard, B, Delalandre, A, Jouzeau, J.-Y, Reboul, P, Lajeunesse, D

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153 MODULATION OF THE PHENOTYPE OF HUMAN OSTEOARTHRITIC SUBCHONDRAL OSTEOBLASTS BY CONJUGATED LIPIDS by Abed, É, Reboul, P, Delalandre, A, Lajeunesse, D

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058 R-SPONDINS ARE NEW PLAYERS IN OSTEOARTHRITIS THAT REGULATE WNT SIGNALING IN OSTEOBLASTS by Abed, É, Chan, T, Delalandre, A, Lajeunesse, D

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241 ELEVATED ENDOGENOUS SCLEROSTIN LEVELS IN OSTEOARTHRITIS SUBCHONDRAL OSTEOBLASTS CONTRIBUTE TO REDUCED WNT/B-CATENIN SIGNALING IN THESE CELLS by Abed, E, Couchourel, D, Delalandre, A, Martel Pelletier, J, Pelletier, J.-P, Lajeunesse, D

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Bronchoalveolar Lavage MMP-9 and TIMP-1 in Preschool Wheezers and Their Relationship to Persistent Wheeze by Erlewyn-Lajeunesse, Michel D S, Hunt, Linda P, Pohunek, Petr, Dobson, Sarah J, Kochhar, Puja, Warner, Jane A, Warner, John O

“…Atopic preschool children are more likely to develop persistent wheezing, which could be a consequence of early airway remodeling. Protease–antiprotease…”
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056 ALTERED WNT/b-CATENIN SIGNALING IN HUMAN OSTEOARTHRITIC SUBCHONDRAL OSTEOBLASTS IS DUE TO DICKKOPF-2 (DKK2) AND PROSTAGLANDIN E2 (PGE2) LEVELS by Chan, T.F, Couchourel, D, Delalandre, A, Lajeunesse, D

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Hyperimmunoglobulin-E syndrome with recurrent infection: A review of current opinion and treatment by Erlewyn-Lajeunesse, Michel D. S.

“…Hyperimmunoglobulin E (hyper‐IgE) syndrome with recurrent infection is a rare idiopathic primary immunodeficiency. It consists of a severe dermatitis with…”
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Subchondral and trabecular bone metabolism regulation in canine experimental knee osteoarthritis by Lavigne, P., Benderdour, M., Lajeunesse, D., Reboul, P., Shi, Q., Pelletier, J.-P., Martel-Pelletier, J., Fernandes, J.C.

“…To determine trabecular and subchondral bone metabolic changes in experimental canine osteoarthritis (OA). OA was induced in 19 dogs by transection of the…”
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E(z): a polycomb group gene or a trithorax group gene? by LaJeunesse, D, Shearn, A

“…The products of the Polycomb group of genes are cooperatively involved in repressing expression of homeotic selector genes outside of their appropriate…”
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IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis by Martel-Pelletier, J, Di Battista, J A, Lajeunesse, D, Pelletier, J P

“…In the context of joint biology, insulin-like growth factor-1 (IGF-1) is the most likely candidate to affect the anabolism of cartilage matrix molecules…”
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Treatment with licofelone prevents abnormal subchondral bone cell metabolism in experimental dog osteoarthritis by Lajeunesse, D, Martel-Pelletier, J, Fernandes, J C, Laufer, S, Pelletier, J-P

“…Objectives: To determine if treatment with licofelone, a combined 5-lipoxygenase and cyclo-oxygenase inhibitor, in vivo in experimental dog osteoarthritis can…”
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