Search Results - "LaGamma, Christina T"

Ventral CA3 Activation Mediates Prophylactic Ketamine Efficacy Against Stress-Induced Depressive-like Behavior by Mastrodonato, Alessia, Martinez, Randy, Pavlova, Ina P., LaGamma, Christina T., Brachman, Rebecca A., Robison, Alfred J., Denny, Christine A.

“…We previously reported that a single injection of ketamine prior to stress protects against the onset of depressive-like behavior and attenuates learned fear…”
Get full text

Prophylactic ketamine alters nucleotide and neurotransmitter metabolism in brain and plasma following stress by McGowan, Josephine C, Hill, Collin, Mastrodonato, Alessia, LaGamma, Christina T, Kitayev, Alexander, Brachman, Rebecca A, Narain, Niven R, Kiebish, Michael A, Denny, Christine A

“…Recently, we have shown that ketamine given prior to stress exposure protects against the development of depressive-like behavior in mice. These data suggest…”
Get full text

Sex-specific neurobiological actions of prophylactic (R,S)-ketamine, (2R,6R)-hydroxynorketamine, and (2S,6S)-hydroxynorketamine by Chen, Briana K, Luna, Victor M, LaGamma, Christina T, Xu, Xiaoming, Deng, Shi-Xian, Suckow, Raymond F, Cooper, Thomas B, Shah, Abhishek, Brachman, Rebecca A, Mendez-David, Indira, David, Denis J, Gardier, Alain M, Landry, Donald W, Denny, Christine A

“…Enhancing stress resilience in at-risk populations could significantly reduce the incidence of stress-related psychiatric disorders. We have previously…”
Get full text

Antidepressant but Not Prophylactic Ketamine Administration Alters Calretinin and Calbindin Expression in the Ventral Hippocampus by LaGamma, Christina T, Tang, William W, Morgan, Ashlea A, McGowan, Josephine Cecelia, Brachman, Rebecca A, Denny, Christine A

“…Ketamine has been found to have rapid, long-lasting antidepressant effects in treatment-resistant (TR) patients with major depressive disorder (MDD). Recently,…”
Get full text

Prophylactic (R,S)-ketamine selectively protects against inflammatory stressors by Mastrodonato, Alessia, Cohensedgh, Omid, LaGamma, Christina T., McGowan, Josephine C., Hunsberger, Holly C., Denny, Christine A.

“…•(R,S)-ketamine attenuates fear following LPS O111:B4 administration.•(R,S)-ketamine decreases behavioral despair following LPS O111:B4…”
Get full text

Prophylactic Ketamine Attenuates Learned Fear by McGowan, Josephine C, LaGamma, Christina T, Lim, Sean C, Tsitsiklis, Melina, Neria, Yuval, Brachman, Rebecca A, Denny, Christine A

“…Ketamine has been reported to be an efficacious antidepressant for major depressive disorder and posttraumatic stress disorder. Most recently, ketamine has…”
Get full text

Traumatic Brain Injury-Induced Fear Generalization in Mice Involves Hippocampal Memory Trace Dysfunction and Is Alleviated by (R,S)-Ketamine by McGowan, Josephine C, Ladner, Liliana R, Shubeck, Claire X, Tapia, Juliana, LaGamma, Christina T, Anqueira-González, Amanda, DeFrancesco, Ariana, Chen, Briana K, Hunsberger, Holly C, Sydnor, Ezra J, Logan, Ryan W, Yu, Tzong-Shiue, Kernie, Steven G, Denny, Christine A

“…Traumatic brain injury (TBI) is a debilitating neurological disorder caused by an impact to the head by an outside force. TBI results in persistent cognitive…”
Get full text

GluN2B on Adult-Born Granule Cells Modulates (R,S)-Ketamine’s Rapid-Acting Effects in Mice by Bulthuis, Nicholas E, McGowan, Josephine C, Ladner, Liliana R, LaGamma, Christina T, Lim, Sean C, Shubeck, Claire X, Brachman, Rebecca A, Sydnor, Ezra, Pavlova, Ina P, Seo, Dong-oh, Drew, Michael R, Denny, Christine A

“…Abstract Background Standard antidepressant treatments often take weeks to reach efficacy and are ineffective for many patients. (R,S)-ketamine, an…”
Get full text