Search Results - "La Porta, C A M"
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Salivary proteomic profile of young healthy subjects
Published in Frontiers in molecular biosciences (30-11-2023)“…The incidence of noncommunicable diseases (NCDs) has been rapidly ramped up worldwide. Hence, there is an urgent need to non-invasively detect NCDs possibly by…”
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Modulation of pro- and anti-apoptotic factors in human melanoma cells exposed to histone deacetylase inhibitors
Published in Apoptosis (London) (01-09-2004)“…Valproic acid (VPA, 2-propylpentanoic acid) is an established drug in the long-term therapy of epilepsy. Recently, VPA was demonstrated to inhibit histone…”
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BRAF V599E mutation occurs in Spitz and Reed naevi
Published in Journal of the European Academy of Dermatology and Venereology (01-10-2006)Get full text
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Inactivation of PEMT2 in hepatocytes initiated by DENA in fasted/refed rats
Published in Biochemical and biophysical research communications (21-07-2006)“…Phosphatidylethanolamine N-methyltransferase (PEMT) is the enzyme that converts phosphatidylethanolamine (PE) into phosphatidylcholine. We have previously…”
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Chromatin and cytoskeletal tethering determine nuclear morphology in progerin expressing cells
Published 16-04-2020“…The nuclear morphology of eukaryotic cells is determined by the interplay between the lamina forming the nuclear skeleton, the chromatin inside the nucleus and…”
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Do cancer cells undergo phenotypic switching? The case for imperfect cancer stem cell markers
Published 28-08-2013“…Scientific Reports | 2 : 441, 2012 The identification of cancer stem cells in vivo and in vitro relies on specific surface markers that should allow to sort…”
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Moderate physical activity during neoadjuvant chemotherapy in breast cancer patients: effect on cancer-related inflammation and pathological complete response—the Neo-Runner study
Published in ESMO open (01-08-2024)“…Physical activity (PA) reduces the risk of developing breast cancer (BC) and mortality rate in BC patients starting PA after diagnosis. Immunomodulation is…”
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Cancer stem cells and therapeutic perspectives
Published in Current medicinal chemistry (01-03-2006)“…The cancer stem cell hypothesis suggests that neoplastic clones are maintained exclusively by a rare fraction of cells with stem cell proprieties. Stem cells…”
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Increased plasma levels of soluble CD40, together with the decrease of TGF beta 1, as possible differential markers of Alzheimer disease
Published in Experimental gerontology (01-10-2004)“…Alzheimer's disease (AD) is a progressive neurodegenerative illness and the most frequent cause of dementia in the elderly. The identification of activated…”
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Low prevalence of Listeria monocytogenes in foods from Italy
Published in Journal of food protection (01-06-2007)“…Listeria monocytogenes is an important foodborne pathogen that causes gastrointestinal disorders, and, especially in immunocompromised people, serious…”
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Different levels of TGF[beta], IL-10, IFN[gamma] and gelatinase A occur in experimental white and black metastases induced by bryostatin 1 or by phorbol ester-treated BL6T murine melanoma cells
Published in Clinical & experimental metastasis (01-07-2000)“…Bryostatin 1 and phorbol esters reduce the intracellular melanin level in high metastatic overexpressing nPKCdelta BL6 (BL6T) cells, thereby inducing white…”
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Higher levels of melanin and inhibition of cdk2 activity in primary human melanoma cells WM115 overexpressing nPKCδ
Published in Melanoma research (01-08-2002)Get full text
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Decrease of TGF-beta1 plasma levels and increase of nitric oxide synthase activity in leukocytes as potential biomarkers of Alzheimer's disease
Published in Experimental gerontology (01-06-2002)“…A variety of inflammatory proteins have been identified in brains of Alzheimer's disease (AD) patients, including inflammatory cytokines, acute phase proteins…”
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Amalgam fillings associated with increased matrix metalloproteinase 9 levels in human saliva
Published in Journal of the European Academy of Dermatology and Venereology (01-07-2005)Get full text
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Overexpression of nPKCδ in BL6 murine melanoma cells enhances TGFβ1 release into the plasma of metastasized animals
Published in Melanoma research (01-12-2000)Get full text
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Overexpression of novel protein kinase C delta in BL6 murine melanoma cells inhibits the proliferative capacity in vitro but enhances the metastatic potential in vivo
Published in Melanoma research (01-04-2000)“…In this study we analysed the effect of overexpressing novel protein kinase C delta isoform (n-PKC delta) on melanin synthesis and metastatic potential in the…”
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Changes in protein kinase C α, δ and in nuclear β isoform expression in tumour and lung metastatic nodules induced by diethylnitrosamine in the rat
Published in Carcinogenesis (New York) (01-04-1997)“…PKC, a family of 11 related isoforms, appears deeply implicated in carcinogenesis and in the metastatic process, however, little being known on the specific…”
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PKC-dependent modulation of IkB alpha-NFkB pathway in low metastatic B16F1 murine melanoma cells and in highly metastatic BL6 cells
Published in Anticancer research (01-07-1998)“…Protein Kinase C (PKC) is a family of at least 11 closely related isoforms with different modality of activation, and intracellular and tissue distribution…”
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Inhibition of protein kinase C-α isoform enhances the P-glycoprotein expression and the survival of LoVo human colon adenocarcinoma cells to doxorubicin exposure
Published in British journal of cancer (01-11-1998)“…The aim of the present paper was to analyse the effect of long-term inhibitory treatment, for at least 7 days, of individual protein kinase C (PKC) isoforms on…”
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