Search Results - "La Perle, Krista MD"
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The roles of phosphotyrosines-294, -404, and -451 in RET/PTC1-induced thyroid tumor formation
Published in Oncogene (21-11-2002)“…RET/PTC1 is a rearranged form of the RET proto-oncogene detected in human papillary thyroid carcinomas. We previously showed that thyroid-targeted expression…”
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Evaluation of a bilayered, micropatterned hydrogel dressing for full-thickness wound healing
Published in Experimental biology and medicine (Maywood, N.J.) (01-05-2016)“…Nearly 12 million wounds are treated in emergency departments throughout the United States every year. The limitations of current treatments for complex,…”
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Deletion of PPARγ in lung macrophages provides an immunoprotective response against M. tuberculosis infection in mice
Published in Tuberculosis (Edinburgh, Scotland) (01-07-2018)“…Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear transcription factor belonging to the superfamily of ligand-activated nuclear receptors…”
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Patterns of scAAV Vector Insertion Associated With Oncogenic Events in a Mouse Model for Genotoxicity
Published in Molecular therapy (01-11-2012)“…Recombinant adeno-associated virus (rAAV) vectors have gained an extensive record of safety and efficacy in animal models of human disease. Infrequent reports…”
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Deletion of PPAR? in lung macrophages provides an immunoprotective response against M. tuberculosis infection in mice
Published in Tuberculosis (Edinburgh, Scotland) (01-07-2018)“…Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear transcription factor belonging to the superfamily of ligand-activated nuclear receptors…”
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6
Targeted deletion of Kcne2 causes gastritis cystica profunda and gastric neoplasia
Published in PloS one (06-07-2010)“…Gastric cancer is the second leading cause of cancer death worldwide. Predisposing factors include achlorhydria, Helicobacter pylori infection, oxyntic atrophy…”
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UVB mutagenesis differs in Nras - and Braf -mutant mouse models of melanoma
Published in Life science alliance (01-09-2021)“…-mutant melanomas are more likely than -mutant melanomas to arise in anatomical locations protected from chronic sun damage. We hypothesized that this…”
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Extra-prostatic Transgene-associated Neoplastic Lesions in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice
Published in Toxicologic pathology (01-02-2015)“…Male transgenic adenocarcinoma of the mouse prostate (TRAMP) mice are frequently used in prostate cancer research because their prostates consistently develop…”
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Cox-2 expression, PGE sub(2 and cytokines production are inhibited by endogenously synthesized n-3 PUFAs in inflamed colon of fat-1 mice)
Published in The Journal of nutritional biochemistry (01-04-2011)“…There is great interest in the role of polyunsaturated fatty acids (PUFAs) in promoting (n-6 class) or inhibiting (n-3 class) inflammation. Mammalian cells are…”
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Pancreaticoduodenal Arterial Rupture and Hemoabdomen in ACI/SegHsd Rats with Polyarteritis Nodosa
Published in Comparative medicine (01-08-2007)“…Many lesions associated with aging have been well-characterized in various strains of rats. Although documented in Sprague- Dawley and spontaneously…”
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