Search Results - "La Casta, A"

Durvalumab plus tremelimumab for the treatment of advanced neuroendocrine neoplasms of gastroenteropancreatic and lung origin by Capdevila, J., Hernando, J., Teule, A., Lopez, C., Garcia-Carbonero, R., Benavent, M., Custodio, A., Garcia-Alvarez, A., Cubillo, A., Alonso, V., Carmona-Bayonas, A., Alonso-Gordoa, T., Crespo, G., Jimenez-Fonseca, P., Blanco, M., Viudez, A., La Casta, A., Sevilla, I., Segura, A., Llanos, M., Landolfi, S., Nuciforo, P., Manzano, J. L.

“…Single immune checkpoint blockade in advanced neuroendocrine neoplasms (NENs) shows limited efficacy; dual checkpoint blockade may improve treatment activity…”
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Biliary tract cancers: SEOM clinical guidelines by Benavides, M., Antón, A., Gallego, J., Gómez, M. A., Jiménez-Gordo, A., La Casta, A., Laquente, B., Macarulla, T., Rodríguez-Mowbray, J. R., Maurel, J.

“…Biliary tract cancer (BTC) is an uncommon and highly fatal malignancy. It is composed of three main different entities; Gall bladder carcinoma (GBC),…”
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Efficacy of lenvatinib in patients with advanced pancreatic (panNETs) and gastrointestinal (giNETs) grade 1/2 (G1/G2) neuroendocrine tumors: Results of the international phase II TALENT trial (GETNE 1509) by Capdevila, J., Fazio, N., Lopez, C., Teule, A., Valle, J.W., Tafuto, S., Custodio, A., Reed, N., Raderer, M., Grande, E., Garcia-Carbonero, R., Jimenez Fonseca, P., Alonso, V., Antonuzzo, L., Spallanzani, A., Berruti, A., Sevilla Garcia, I., La Casta, A., Hernando, J., Ibrahim, T.

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Association of Circulating Tumor Cells and Tumor Molecular Profile With Clinical Outcomes in Patients With Previously Untreated Metastatic Colorectal Cancer: A Pooled Analysis of the Phase III VISNÚ-1 and Phase II VISNÚ-2 Randomized Trials by Jiménez-Fonseca, P., Sastre, J., García-Alfonso, P., Gómez-España, M.A., Salud, A., Gil, S., Rivera, F., Reina, J.J., Quintero, G., Valladares-Ayerbes, M., Safont, M.J., La Casta, A., Robles-Díaz, L., García-Paredes, B., López López, R., Guillot, M., Gallego, J., Alonso-Orduña, V., Diaz-Rubio, E., Aranda, E.

“…The bCTC count is a well-established prognostic biomarker in mCRC, as well as in other tumor types. The aim of this analysis was to evaluate the…”
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Development and internal validation of a predictive nomogram of progression-free survival in well-differentiated stage IV gastroenteropancreatic neuroendocrine tumours treated with somatostatin analogues: GETNE-TRASGU study by Garcia-Carbonero, R., Alonso, V., Capdevila, J., Sanchez Canovas, M., Alonso, T., Benavent, M., Custodio, A., Crespo Herrero, G., Lopez, C., Hernando, J., Riesco Martinez, M.C., Escudero, P., Gallego Plazas, J., Marazuela, M., Diaz, J.A., Llanos-Munoz, M., La Casta, A., Percovich, J.C., Jimenez-Fonseca, P., Carmona-Bayonas, A.

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Influence of BRAF and PIK3CA mutations on the efficacy of FOLFIRI plus bevacizumab or cetuximab as first-line therapy in patients with RAS wild-type metastatic colorectal carcinoma and <3 baseline circulating tumour cells: the randomised phase II VISNÚ-2 study by Sastre, J., García-Alfonso, P., Viéitez, J.M., Cano, M.T., Rivera, F., Reina-Zoilo, J.J., Salud-Salvia, A., Quintero, G., Robles-Díaz, L., Safont, M.J., La Casta, A., Gil, S., Polo, E., Asensio-Martínez, E., García-Paredes, B., López, R.L., Guillot, M., Valladares-Ayerbes, M., Aranda, E., Díaz-Rubio, E., Viéitez, J.M., Jiménez, P., Aguilar, E. Aranda, Gómez, A., Gil Calle, S., Salud, A., Valladares, M., Graña, B., García-Alfonso, P., Rivera, F., Quintero, G., Reina, J.J., González Flores, E., Salgado, M., Grande, E., Guillén, C., Garcia Carbonero, R., Flor, M.J., Safont, M.J., La Casta, A., Arévalo, S., Sastre, J., López López, R., Manzano, H., Guillot, M., Hernández Yagüe, X., Arrivi, A., Falcó, E., Gallego, J., Escudero, P., Cabezas, I., Juárez, A., Gálvez, E., Grávalos, C., Robles, L., Polo, E., Dueñas, R., Campos, J.M., Albert, A., Salinas, P., Montagut, C., Provencio, M., Ruiz Casado, A., Muñoz, J., Gil Raga, M., Chilet, M.R., González González, F.J., Massutí, B., López, A., Aparicio, J., Marín, M., Alfaro, J., Zanui, M., Gutiérrez Abad, D., García Tapiador, A.M., García-Girón, C., Molina Saera, J., Torres Sánchez, E., López, I., Bosch, C., Valero, J., Martínez de Prado, P.

“…We explored the influence of BRAF and PIK3CA mutational status on the efficacy of bevacizumab or cetuximab plus 5-fluorouracil/leucovorin and irinotecan…”
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Bridging the equity gap in patient education: the biliary tract cancer BABEL project by Casolino, Raffaella, Braconi, Chiara, Prete, MG, González Romero, F, Castro, RE, Banales, JM, Cardinale, V, Morement, H, Milne, J, Krawczyk, M, Krupa, L, Anwar, MM, Poles, ES, Merz, V, Perra, T, Porcu, A, Megdanova, V, Popova, Y, Meneses-Medina, MI, Reyes Mondragón, AL, Burguete-Torres, A, Brandão Rego, I, Magalhães, J, Liz Pimenta, J, Silva, J, João Sousa, M, Custódio, S, Costa, T, Cojocaru, FD, Drug, VL, Hassan, SU, Ain Azam, NU, Kupcinskas, J, Kreivenaite, E, Morkunas, E, Nikolaieva, O, Calvisi, D, Evert, M, Terhuja, N, Das, A, Hoang, KD, Nguyen, HH, Evseev, V, Khuntikeo, N, Abdihamid, O, Mariamidze, E, Tsiklauri, K, Koyyala, VPB, Medisetty, P, Digumarti, L, Digumarti, RR, Konkalla, VLA, Mitra, S, Sud, R, Parikh, P, Gupta, SK, Sen, S, Chanda, S, das, D, Domadia, K, Goyal, P, Goyal, S, Dhamne, N, Acharya, PV, Jain, P, Sharma, M, War, GA, Singh, SR, Dodagoudar, C, Patnaik, RS, Mashahary, SS, Paul, R, Kannan, T, Goel, V, Patnaik, N, Jajodia, A, Pasricha, S, Gupta, M, Agarwal, C, Mondal, DK, BP, A, Joga, S, Mullapally, SK, Choudhary, P, Saini, R, Selvaraju, T, Pahwa, S, Durga, G, Maheshwari, U, Dhaka, S, Lindsay, S, Omar, A, La Casta Muñoa, A

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Splanchnic vein thrombosis in cholangiocarcinoma. A retrospective observational study. Donostia University Hospital by Landa, A., Sánchez, B., Diaz, M., Otaño, M., Medina, A., Catalán, C. Fernández, Santos, A., Izquierdo, L., La Casta Muñoa, A.

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1099MO Durvalumab plus tremelimumab influence on response to subsequent treatments in patients with neuroendocrine neoplasms (NENs) of gastroenteropancreatic and lung origins: Results from the phase II DUNE trial (GETNE 1601) by Hernando, J., Manzano, J.L., Teule, A., López, C., Garcia-Carbonero, R., Benavent Viñuales, M., Custodio, A., Cubillo, A., Alonso, V., Alonso-Gordoa, T., Carmona-Bayonas, A., Crespo, G., Blanco, M., Jimenez-Fonseca, P., Viudez, A., La Casta, A., Sevilla, I., Llanos, M., Segura, Á., Capdevila, J.

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1097O The AXINET trial (GETNE1107): Axitinib plus octreotide LAR improves PFS by blinded central radiological assessment vs placebo plus octreotide LAR in G1-2 extrapancreatic NETs by Garcia-Carbonero, R., Benavent, M., Jiménez Fonseca, P., Castellano, D., Alonso-Gordoa, T., Teulé, A., Custodio, A., Tafuto, S., La Casta, A., Spada, F., López, C., Ibrahim, T., Silva, M.J. Villanueva, Iranzo, V., García-Alfonso, P., González-Flores, E., Grande, E., Crespo, G., Carmona-Bayonas, A., Capdevila, J.

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1107P Durvalumab plus tremelimumab in patients with grade 3 neuroendocrine neoplasms of gastroenteropancreatic origin: Updated results from the multicenter phase II DUNE trial (GETNE 1601) by Capdevila, J., Landolfi, S., Hernando, J., Teule, A., Garcia-Carbonero, R., Custodio, A., Cubillo, A., Alonso-Gordoa, T., Carmona-Bayonas, A., Crespo, G., Blanco, M., Viudez, A., La Casta, A., Sevilla, I., Segura, Á., López, C., Benavent Viñuales, M., Nuciforo, P., Manzano, J.L.

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731P - Liver metastases (LM) from intrahepatic cholangiocarcinoma (iCCA): Outcomes from the European Network for the study of cholangiocarcinoma (ENS-CCA) registry and implications on current American Joint Committee on Cancer (AJCC) staging by Lamarca, A., Santos, A., Utpatel, K., La Casta, A., Stock, S., Forner, A., Adeva Alfonso, J., Folseraas, T., Fabris, L., Macias, R., Krawczyk, M., Krawczyk, M., Cardinale, V., Braconi, C., Alvaro, D., Evert, M., Bañales, J., Valle, J.W.

“…The AJCC classifies LM of iCCA as early stage: T2b [stage II/IVa (AJCCv.7) and stage II/III (AJCCv.8) if N0/N1, respectively]; in contrast, LM are perceived by…”
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Liver metastases (LM) from intrahepatic cholangiocarcinoma (iCCA): Outcomes from the European Network for the study of cholangiocarcinoma (ENS-CCA) registry and implications on current American Joint Committee on Cancer (AJCC) staging by Lamarca, A., Santos, A., Utpatel, K., La Casta, A., Stock, S., Forner, A., Adeva Alfonso, J., Folseraas, T., Fabris, L., Macias, R., Krawczyk, M., Cardinale, V., Braconi, C., Alvaro, D., Evert, M., Bañales, J., Valle, J.W.

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731PLiver metastases (LM) from intrahepatic cholangiocarcinoma (iCCA): Outcomes from the European Network for the study of cholangiocarcinoma (ENS-CCA) registry and implications on current American Joint Committee on Cancer (AJCC) staging by Lamarca, A, Santos, A, Utpatel, K, La Casta, A, Stock, S, Forner, A, Adeva Alfonso, J, Folseraas, T, Fabris, L, Macias, R, Krawczyk, M, Krawczyk, M, Cardinale, V, Braconi, C, Alvaro, D, Evert, M, Bañales, J, Valle, J W

“…Abstract Background The AJCC classifies LM of iCCA as early stage: T2b [stage II/IVa (AJCCv.7) and stage II/III (AJCCv.8) if N0/N1, respectively]; in contrast,…”
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A phase I and randomized phase II trial to evaluate the efficacy and safety of nab-paclitaxel (nab-P) in combination with gemcitabine (G) for the treatment of patients with ECOG 2 advanced pancreatic cancer (PDAC) by Hidalgo, M., Pazo-Cid, R., Guillen-Ponce, C., López, R., Vera, R., Reboredo, M., Muñoz, A., Martinez de Castro, E., Díaz Beveridge, R., La Casta, A., Martin-Valades, J.I., Cubillo, A., Martínez-Galán, J., Ales, I., Sastre, J., Macarulla Mercade, T.

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1315PDevelopment and internal validation of a predictive nomogram of progression-free survival in well-differentiated stage IV gastroenteropancreatic neuroendocrine tumours treated with somatostatin analogues: GETNE-TRASGU study by Garcia-Carbonero, R, Alonso, V, Capdevila, J, Sanchez Canovas, M, Alonso, T, Benavent, M, Custodio, A, Crespo Herrero, G, Lopez, C, Hernando, J, Riesco Martinez, M C, Escudero, P, Gallego Plazas, J, Marazuela, M, Diaz, J A, Llanos-Munoz, M, La Casta, A, Percovich, J C, Jimenez-Fonseca, P, Carmona-Bayonas, A

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1307OEfficacy of lenvatinib in patients with advanced pancreatic (panNETs) and gastrointestinal (giNETs) grade 1/2 (G1/G2) neuroendocrine tumors: Results of the international phase II TALENT trial (GETNE 1509) by Capdevila, J, Fazio, N, Lopez, C, Teule, A, Valle, J W, Tafuto, S, Custodio, A, Reed, N, Raderer, M, Grande, E, Garcia-Carbonero, R, Jimenez Fonseca, P, Alonso, V, Antonuzzo, L, Spallanzani, A, Berruti, A, Sevilla Garcia, I, La Casta, A, Hernando, J, Ibrahim, T

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First-Line Biological Agents Plus Chemotherapy in Older Patients with Metastatic Colorectal Cancer: A Retrospective Pooled Analysis by García-Alfonso, Pilar, Díaz-Rubio, Eduardo, Abad, Albert, Carrato, Alfredo, Massutí, Bartomeu, Ortiz-Morales, María José, Manzano Mozo, José Luis, Muñoz, Andrés, Durán, Gema, Sastre, Javier, Safont, María José, Ferreiro, Reyes, Rivera, Fernando, González, Encarnación, Valladares-Ayerbes, Manuel, Grávalos, Cristina, Alonso-Orduña, Vicente, Viéitez, José María, Yubero, Alfonso, Aranda, Enrique

“…Background Biologicals, in combination with chemotherapy, are recommended as first-line treatment of metastatic colorectal cancer (mCRC); however, evidence…”
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P-272 Phase II study of Regorafenib as single agent for the treatment of patients with metastatic colorectal cancer with any RAS or BRAF mutation and previously treated with FOLFOXIRI plus bevacizumab by García Alfonso, P., Ortiz, M.J., Durán, G., Falcó, E., Muñoz, A., García-Paredes, B., Salgado, M., López-Ladrón, A., Vieitez de Prado, J.M., Valladares, M., Salud, A., Guillén-Ponce, C., Lopez, R., Robles, L., Juárez, A., Serrano, S., Montagut, C., Zanui, M., Gil Raga, M., La Casta, A., Benavides, M., Aranda, E.

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P-247Splanchnic vein thrombosis in cholangiocarcinoma. A retrospective observational study. Donostia University Hospital by Landa, A, Sánchez, B, Diaz, M, Otaño, M, Medina, A, Catalán, C Fernández, Santos, A, Izquierdo, L, La Casta Muñoa, A

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