Search Results - "Lättekivi, Freddy"
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Zeta Potential of Extracellular Vesicles: Toward Understanding the Attributes that Determine Colloidal Stability
Published in ACS omega (14-07-2020)“…Extracellular vesicles (EVs), including exosomes and microvesicles (<200 nm), play a vital role in intercellular communication and carry a net negative surface…”
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Oviduct as a sensor of embryo quality: deciphering the extracellular vesicle (EV)-mediated embryo-maternal dialogue
Published in Journal of molecular medicine (Berlin, Germany) (01-05-2021)“…Embryo-derived extracellular vesicles (EVs) may play a role in mediating the embryo-maternal dialogue at the oviduct, potentially carrying signals reflecting…”
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miRNA expression profiles of the perilesional skin of atopic dermatitis and psoriasis patients are highly similar
Published in Scientific reports (31-12-2022)“…Atopic dermatitis (AD) and psoriasis vulgaris (PV) are chronic inflammatory skin diseases with heterogeneous molecular backgrounds. MicroRNAs (miRNAs)…”
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Decidualized endometrial stromal cells present with altered androgen response in PCOS
Published in Scientific reports (11-08-2021)“…Hyperandrogenic women with PCOS show disrupted decidualization (DE) and placentation. Dihydrotestosterone (DHT) is reported to enhance DE in non-PCOS…”
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Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal communication
Published in Reproductive biology and endocrinology (21-07-2021)“…The period of time when the embryo and the endometrium undergo significant morphological alterations to facilitate a successful implantation-known as "window…”
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Transcriptomic profiles in Parkinson’s disease
Published in Experimental biology and medicine (Maywood, N.J.) (01-03-2021)“…Transcriptomics in Parkinson’s disease offers insights into the pathogenesis of Parkinson’s disease but obtaining brain tissue has limitations. In order to…”
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Bovine Follicular Fluid and Extracellular Vesicles Derived from Follicular Fluid Alter the Bovine Oviductal Epithelial Cells Transcriptome
Published in International journal of molecular sciences (28-07-2020)“…While follicular fluid (FF) is well known to provide an optimal environment for oogenesis, its functional roles following its release into the oviduct during…”
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Specific trophoblast transcripts transferred by extracellular vesicles affect gene expression in endometrial epithelial cells and may have a role in embryo-maternal crosstalk
Published in Cell communication and signaling (14-11-2019)“…Successful establishment of pregnancy hinges on appropriate communication between the embryo and the uterus prior to implantation, but the nature of this…”
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Measurement of the Size and Concentration and Zeta Potential of Extracellular Vesicles Using Nanoparticle Tracking Analyzer
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…Extracellular vesicles (EVs) are membrane-bound nanoparticles that are secreted by most cell types with an emerging role in cellular communication and…”
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Profiling Blood Serum Extracellular Vesicles in Plaque Psoriasis and Psoriatic Arthritis Patients Reveals Potential Disease Biomarkers
Published in International journal of molecular sciences (04-04-2022)“…Psoriasis vulgaris (PsV) and psoriatic arthritis (PsA) are inflammatory diseases with unresolved pathophysiological aspects. Extracellular vesicles (EVs) play…”
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Individually cultured bovine embryos produce extracellular vesicles that have the potential to be used as non-invasive embryo quality markers
Published in Theriogenology (01-06-2020)“…Extracellular vesicles (EVs) are membrane-bound biological nanoparticles (NPs) and have gained wide attention as potential biomarkers. We aimed to isolate and…”
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Long-Term Elevated Inflammatory Protein Levels in Asymptomatic SARS-CoV-2 Infected Individuals
Published in Frontiers in immunology (17-09-2021)“…The clinical features of SARS-CoV-2 infection range from asymptomatic to severe disease with life-threatening complications. Understanding the persistence of…”
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Time-critical influences of gestational diet in a seahorse model of male pregnancy
Published in Journal of experimental biology (07-02-2020)“…Sex role reversal is not uncommon in the animal kingdom but is taken to the extreme by the Syngnathidae, in which male pregnancy is one of the most astonishing…”
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Analysis of repetitive element expression in the blood and skin of patients with Parkinson’s disease identifies differential expression of satellite elements
Published in Scientific reports (13-03-2019)“…Repetitive elements (RE) constitute the majority of the human genome and have a range of functions both structural and regulatory on genomic function and gene…”
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Multicomponent Biomarker Approach Improves the Accuracy of Diagnostic Biomarkers for Psoriasis Vulgaris
Published in Acta dermato-venereologica (01-12-2019)“…Accurate biomarker-based diagnosis of psoriasis vulgaris has remained a challenge; no reliable disease-specific biomarkers have yet been identified. There are…”
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Bovine Follicular Fluid Derived Extracellular Vesicles Modulate the Viability, Capacitation and Acrosome Reaction of Bull Spermatozoa
Published in Biology (Basel, Switzerland) (01-11-2021)“…While follicular fluid (FF) is known to enhance the functional properties of spermatozoa, the role of FF-derived extracellular vesicles (EVs) in this respect…”
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Prevalence of SARS-CoV-2 IgG antibodies and their association with clinical symptoms of COVID-19 in Estonia (KoroSero-EST-1 study)
Published in Vaccine (07-09-2021)“…In Estonia, during the first wave of COVID-19 total number of cases confirmed by PCR was 13.3/10,000, similar in most regions, including capital Tallinn, but…”
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Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization
Published in Human reproduction (Oxford) (01-08-2021)“…Abstract STUDY QUESTION Can a combination of the focussed protein kinase assays and a wide-scale proteomic screen pinpoint novel, clinically relevant players…”
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Spermatozoa induce transcriptomic alterations in bovine oviductal epithelial cells prior to initial contact
Published in Journal of cell communication and signaling (01-12-2020)“…The capability of spermatozoa to directly influence maternal gene expression is already established. Indeed, some of the changes induced by spermatozoa may…”
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Transcriptional landscape of human endogenous retroviruses (HERVs) and other repetitive elements in psoriatic skin
Published in Scientific reports (12-03-2018)“…Human endogenous retrovirus (HERV) sequences make up at least 8% of the human genome. Transcripts originating from these loci as well as proteins encoded by…”
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