Search Results - "La, Xiaoqin"
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Ferulic Acid and P-Coumaric Acid Synergistically Attenuate Non-Alcoholic Fatty Liver Disease through HDAC1/PPARG-Mediated Free Fatty Acid Uptake
Published in International journal of molecular sciences (04-12-2022)“…Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease and has become a growing public health concern worldwide. Polyphenols may improve…”
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Polyphenols from whole millet grain(Setaria italica) alleviate glucose and lipid homeostasis in diet-induced-obese mice by increasing endogenous GLP-1
Published in Journal of the science of food and agriculture (01-12-2023)“…Foxtail millet (Setaria italica) is a whole millet grain that has been considered for improving the disorder of glucose and lipid metabolism. The purpose of…”
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Gastroprotective Effect of Isoferulic Acid Derived from Foxtail Millet Bran against Ethanol-Induced Gastric Mucosal Injury by Enhancing GALNT2 Enzyme Activity
Published in Nutrients (05-07-2024)“…Excessive alcohol consumption has led to the prevalence of gastrointestinal ailments. Alleviating gastric disorders attributed to alcohol-induced thinning of…”
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Salvianolic acid A inhibits tumor-associated angiogenesis by blocking GRP78 secretion
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-04-2019)“…Glucose-regulated protein 78 (GRP78) often highly expresses in a wide range of tumors, which plays promotive functions due to its diversity of location in the…”
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Tumor-associated macrophages confer colorectal cancer 5-fluorouracil resistance by promoting MRP1 membrane translocation via an intercellular CXCL17/CXCL22–CCR4–ATF6–GRP78 axis
Published in Cell death & disease (01-09-2023)“…Chemotherapy represents a major type of clinical treatment against colorectal cancer (CRC). Aberrant drug efflux mediated by transporters acts as a key…”
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The phytochemical vitexin and syringic acid derived from foxtail fillet bran inhibit breast cancer cells proliferation via GRP78/SREBP-1/SCD1 signaling axis
Published in Journal of functional foods (01-10-2021)“…[Display omitted] •BPIS specifically inhibited breast cancer via blocking the conversion of SFA to MUFA.•VT and SA were the anti-breast cancer active…”
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Isorhamnetin in Quinoa Whole-Grain Flavonoids Intervenes in Non-Alcoholic Fatty Liver Disease by Modulating Bile Acid Metabolism through Regulation of FXR Expression
Published in Foods (26-09-2024)“…Non-alcoholic fatty liver disease (NAFLD) is a severe hepatic health threat with no effective treatment. Based on the results that Chenopodium quinoa Willd…”
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(−)-Epigallocatechin Gallate (EGCG) Enhances the Sensitivity of Colorectal Cancer Cells to 5‑FU by Inhibiting GRP78/NF-κB/miR-155-5p/MDR1 Pathway
Published in Journal of agricultural and food chemistry (06-03-2019)“…Green tea accounts for approximately 20% of the world’s total tea yield. (−)-Epigallocatechin gallate (EGCG) is an active catechin in green tea, which…”
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Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells
Published in Oncotarget (28-03-2017)“…Berberine, an isoquinoline alkaloid extracted from Coptidis Rhizoma, has been shown to induce cancer cell autophagic death. Glucose regulated protein 78…”
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QPH-FR: A Novel Quinoa Peptide Enhances Chemosensitivity by Targeting Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 5 in Colorectal Cancer
Published in Journal of agricultural and food chemistry (07-08-2024)“…Chemoresistance is one of the difficulties in the treatment of colorectal cancer (CRC), and the enhanced stemness of tumor cells is the underlying contributing…”
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Isolation and purification of flavonoids from quinoa whole grain and its inhibitory effect on lipid accumulation in nonalcoholic fatty liver disease by inhibiting the expression of CD36 and FASN
Published in Journal of the science of food and agriculture (21-09-2024)“…Nonalcoholic fatty liver disease (NAFLD), a chronic metabolic disorder marked by excessive lipid deposition, represents a considerable health burden with no…”
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Tumor-secreted GRP78 facilitates the migration of macrophages into tumors by promoting cytoskeleton remodeling
Published in Cellular signalling (01-08-2019)“…Glucose-regulated protein 78 (GRP78), an important molecular chaperone in the endoplasmic reticulum, is often over-expressed in the central region of advanced…”
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Salvianolic acid A attenuates inflammation-mediated atherosclerosis by suppressing GRP78 secretion of endothelial cells
Published in Journal of ethnopharmacology (23-05-2023)“…Salvianolic acid A (SAA) is the main active component of the classic anti-atherosclerotic drug Salvia miltiorrhiza Bunge. Inflammation-induced infiltration of…”
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Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism
Published in Cellular signalling (01-08-2023)“…Macrophages in hypoxic regions of advanced colorectal tumors often exhibit M2-type features, but prefer oxygen-consuming lipid catabolism, which is…”
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GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages
Published in Cellular signalling (01-09-2017)“…Macrophages are the main immune-competent cells that infiltrate in tumors. Tumor-associated macrophages (TAMs), termed M2 macrophages, facilitate tumor…”
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RETRACTED: Tumor-secreted GRP78 facilitates the migration of macrophages into tumors by promoting cytoskeleton remodeling
Published in Cellular signalling (01-08-2019)“…This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/locate/withdrawalpolicy). This article has been…”
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Ajuba receptor mediates the internalization of tumor-secreted GRP78 into macrophages through different endocytosis pathways
Published in Oncotarget (20-03-2018)“…Glucose-regulated protein 78 (GRP78), an ER chaperone, is overexpressed in cancer cells. Solid tumor cells can secrete GRP78 that can promote tumor…”
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Design, purification and assessment of GRP78 binding peptide-linked Subunit A of Subtilase cytotoxic for targeting cancer cells
Published in BMC biotechnology (01-09-2016)“…Targeted therapies for cancer, especially the malignant cancer, are always restricted by the deficiency of tumor-specific drug delivery methods. Subtilase…”
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