Search Results - "La, Mei K."
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Analysis of the Role of Hematopoietic Stem-Cell Transplantation in Infants With Acute Lymphoblastic Leukemia in First Remission and MLL Gene Rearrangements: A Report From the Children's Oncology Group
Published in Journal of clinical oncology (10-01-2011)“…Although the majority of children with acute lymphoblastic leukemia (ALL) are cured with current therapy, the event-free survival (EFS) of infants with ALL,…”
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Outcome After Relapse Among Children With Standard-Risk Acute Lymphoblastic Leukemia: Children's Oncology Group Study CCG-1952
Published in Journal of clinical oncology (20-12-2007)“…The event-free survival (EFS) of children with standard-risk acute lymphoblastic leukemia (SR-ALL) is now more than 80%. However, prognosis after relapse…”
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Young Adults With Acute Lymphoblastic Leukemia Have an Excellent Outcome With Chemotherapy Alone and Benefit From Intensive Postinduction Treatment: A Report From the Children's Oncology Group
Published in Journal of clinical oncology (01-11-2009)“…Patients 16 to 21 years of age with acute lymphoblastic leukemia (ALL) have an inferior outcome compared with younger children, leading some medical…”
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Early postinduction intensification therapy improves survival for children and adolescents with high-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group
Published in Blood (01-03-2008)“…Longer and more intensive postinduction intensification (PII) improved the outcome of children and adolescents with “higher risk” acute lymphoblastic leukemia…”
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Dexamethasone versus prednisone and daily oral versus weekly intravenous mercaptopurine for patients with standard-risk acute lymphoblastic leukemia: a report from the Children's Cancer Group
Published in Blood (15-05-2003)“…Conventional therapy for childhood acute lymphoblastic leukemia (ALL) includes prednisone and oral 6-mercaptopurine. Prior observations suggested potential…”
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Abnormalities of chromosome bands 15q13‐15 in childhood acute lymphoblastic leukemia
Published in Cancer (15-02-2002)“…BACKGROUND Recurring breakpoints in chromosome bands 15q13‐15 occur infrequently in leukemia. To the authors' knowledge, the clinical significance of these…”
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Lymphoblast biology and outcome among children with Down syndrome and ALL treated on CCG-1952
Published in Pediatric Blood & Cancer (01-01-2005)“…Background Patients with Down syndrome (DS) and standard risk (SR) acute lymphoblastic leukemia (ALL‐DS) are reported to have inferior event free (EFS) and…”
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Double-delayed intensification improves event-free survival for children with intermediate-risk acute lymphoblastic leukemia: a report from the Children's Cancer Group
Published in Blood (01-02-2002)“…Addition of a delayed-intensification (DI) phase after standard induction/consolidation therapy was previously shown to improve outcome for patients younger…”
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Intravenous 6-mercaptopurine decreases salvage after relapse in childhood acute lymphoblastic leukemia: A report from the Children's Cancer Group study CCG 1922
Published in Pediatric Blood & Cancer (01-07-2005)“…Purpose To compare outcomes of patients with NCI standard risk acute lymphoblastic leukemia (ALL) who relapsed after being randomized to receive either oral or…”
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Survival after Relapse in Higher Risk Acute Lymphoblastic Leukemia (ALL) in Children and Adolescents Is Independent of Prior Treatment Intensity: A Report from the Children's Oncology Group (COG)
Published in Blood (16-11-2008)“…While intensification of therapy has improved event-free survival (EFS) and survival in newly diagnosed patients, outcomes after relapse have proved more…”
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Escalating Dose Intravenous Methotrexate without Leucovorin Rescue during Interim Maintenance Is Superior to Oral Methotrexate for Children with Standard Risk Acute Lymphoblastic Leukemia (SR-ALL): Children's Oncology Group Study 1991
Published in Blood (16-11-2008)“…A substantial number of relapses derive from the NCI standard risk population. CCG-1991 tested two components of the successful COG augmented “BFM” regimen (N…”
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Early Marrow Response in CCG-1952: The Prognostic Impact of Poor Day 14 Marrow Response Is Powerful and Only Partially Reversible with Intensified Therapy
Published in Blood (16-11-2005)“…Microscopic assessment of bone marrow response on Day 7 and/or Day 14 of induction therapy remains a powerful predictor of long-term outcome in childhood acute…”
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Outcome after Relapse among Children with Standard Risk (SR) ALL Treated on CCG-1952
Published in Blood (16-11-2004)“…The event-free survival (EFS) of children with SR-ALL is now > 80%. Nonetheless, ALL relapse remains a major problem in pediatric cancer, and optimal therapy…”
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