Search Results - "LYNCH, John K"

Predictors of Acute Stroke Mimics in 8187 Patients Referred to a Stroke Service by Merino, José G., MD, MPhil, Luby, Marie, PhD, Benson, Richard T., MD, PhD, Davis, Lisa A., RN, Hsia, Amie W., MD, Latour, Lawrence L., PhD, Lynch, John K., DO, Warach, Steven, MD, PhD

“…Background Some patients seen by a stroke team do not have cerebrovascular disease but a condition that mimics stroke. The purpose of this study was to…”
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Effects of conjugated equine estrogen on stroke in the Women's Health Initiative by HENDRIX, Susan L, WASSERTHEIL-SMOLLER, Sylvia, BURING, Julie E, CRIQUI, Michael H, HERRINGTON, David, LYNCH, John K, RAPP, Stephen R, TORNER, James, JOHNSON, Karen C, HOWARD, Barbara V, KOOPERBERG, Charles, ROSSOUW, Jacques E, TREVISAN, Maurizio, ARAGAKI, Aaron, BAIRD, Alison E, BRAY, Paul F

“…The Women's Health Initiative (WHI) Estrogen Alone trial assessed the balance of benefits and risks of hormone use in healthy postmenopausal women. The trial…”
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Comparison of Hemorrhage on CT Versus MRI After Thrombectomy: The HECATE Study by Hsia, Amie W., Latour, Lawrence L., Somani, Sana, Lomahan, Carolyn A., Kim, Yongwoo, Lynch, John K., Luby, Marie

“…Background The characterization of hemorrhage following acute stroke intervention has largely been computed tomography (CT) based. We sought to compare…”
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Lipid and Lipoprotein Biomarkers and the Risk of Ischemic Stroke in Postmenopausal Women by BERGER, Jeffrey S, MCGINN, Aileen P, ROSENBAUM, Daniel M, WASSERTHEIL-SMOLLER, Sylvia, HOWARD, Barbara V, KULLER, Lewis, MANSON, Joann E, OTVOS, Jim, DAVID CURB, J, EATON, Charles B, KAPLAN, Robert C, LYNCH, John K

“…Few studies simultaneously investigated lipids and lipoprotein biomarkers as predictors of ischemic stroke. The value of these biomarkers as independent…”
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Discovery of Potent, Selective, Orally Bioavailable Stearoyl-CoA Desaturase 1 Inhibitors by Liu, Gang, Lynch, John K, Freeman, Jennifer, Liu, Bo, Xin, Zhili, Zhao, Hongyu, Serby, Michael D, Kym, Philip R, Suhar, Tom S, Smith, Harriet T, Cao, Ning, Yang, Ruojing, Janis, Rich S, Krauser, Joel A, Cepa, Steven P, Beno, David W. A, Sham, Hing L, Collins, Christine A, Surowy, Teresa K, Camp, Heidi S

“…Stearoyl-CoA desaturase 1 (SCD1) catalyzes the committed step in the biosynthesis of monounsaturated fatty acids from saturated, long-chain fatty acids…”
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Walking Speed and Risk of Incident Ischemic Stroke Among Postmenopausal Women by MCGINN, Aileen P, KAPLAN, Robert C, WASSERTHEIL-SMOLLER, Sylvia, VERGHESE, Joe, ROSENBAUM, Daniel M, PSATY, Bruce M, BAIRD, Alison E, LYNCH, John K, WOLF, Philip A, KOOPERBERG, Charles, LARSON, Joseph C

“…Walking speed is a simple, reliable, and valid measure of functional status that has been shown to be strongly correlated with age-related outcomes and may be…”
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Diffuse Fluid-Attenuated Inversion Recovery Hyperintensity in Subarachnoid Space Following Cerebral Angiography and Intravenous Thrombolysis by Zand, Ramin, MD, MPH, Male, Shailesh, MD, Lynch, John K., DO, MPH

“…Objective Transient cortical blindness (TCB) is a relatively rare but well-recognized complication following cardiovascular and cerebral angiography. Methods A…”
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Neuronal Nicotinic Acetylcholine Receptors as Targets for Drug Discovery by Holladay, Mark W, Dart, Michael J, Lynch, John K

“…Until recently, research on (S)-(-)-nicotine (hereafter simply nicotine) and nicotinic acetylcholine receptors (nAChRs) emphasized two principal aspects. The…”
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Recurrent thrombolysis of a stuttering lacunar infarction captured on serial MRIs by Naqvi, Imama, Simpkins, Alexis N., Cullison, Kaylie, Elliott, Emily, Reyes, Dennys, Leigh, Richard, Lynch, John K.

“…Lacunar strokes account for about a fourth of all ischemic strokes. Pontine infarcts often present with stuttering symptoms, referred to as pontine warning…”
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Perfusion Deficits and Association with Clinical Outcome in Patients with Anterior Choroidal Artery Stroke by Alqahtani, Saeed A., MD, Luby, Marie, PhD, Nadareishvili, Zurab, MD, PhD, Benson, Richard T., MD, PhD, Hsia, Amie W., MD, Leigh, Richard, MD, Lynch, John K., DO, MPH

“…Background and Purpose Anterior choroidal artery (AChA) strokes have a varied pattern of tissue injury, prognosis, and clinical outcome. It is unclear whether…”
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Advances in the Diagnosis and Treatment of Pediatric Arterial Ischemic Stroke by Sun, Lisa R., Lynch, John K.

“…Though rare, stroke in infants and children is an important cause of mortality and chronic morbidity in the pediatric population. Neuroimaging advances and…”
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Visual Perfusion―Diffusion Mismatch Is Equivalent to Quantitative Mismatch by LUBY, Marie, KU, Katherine D, LATOUR, Lawrence L, MERINO, José G, HSIA, Amie W, LYNCH, John K, WARACH, Steven

“…The concept of stroke MRI mismatch based on qualitative evaluation of diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) has been applied in…”
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Symptomatic neonatal arterial ischemic stroke: the International Pediatric Stroke Study by Kirton, Adam, Armstrong-Wells, Jennifer, Chang, Taeun, Deveber, Gabrielle, Rivkin, Michael J, Hernandez, Marta, Carpenter, Jessica, Yager, Jerome Y, Lynch, John K, Ferriero, Donna M

“…Neonatal arterial ischemic stroke (AIS) has emerged as a leading cause of perinatal brain injury, cerebral palsy, and lifelong disability. The pathogenesis is…”
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Estimating Perfusion Deficits in Acute Stroke Patients Without Perfusion Imaging by Reyes, Dennys, Simpkins, Alexis N., Hitomi, Emi, Lynch, John K., Hsia, Amie W., Nadareishvili, Zurab, Luby, Marie, Latour, Lawrence L., Leigh, Richard

“…Background: Perfusion weighted imaging (PWI) is critical for determining whether stroke patients presenting in an extended time window are candidates for…”
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MRI-based thrombolytic therapy in patients with acute ischemic stroke presenting with a low NIHSS by Majidi, Shahram, Luby, Marie, Lynch, John K, Hsia, Amie W, Benson, Richard T, Kalaria, Chandni P, Nadareishvili, Zurab, Latour, Lawrence L, Leigh, Richard

“…OBJECTIVETreatment of patients with stroke presenting with minor deficits remains controversial, and the recent Potential of rtPA for Ischemic Strokes with…”
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Screening with MRI for Accurate and Rapid Stroke Treatment: SMART by Shah, Shreyansh, Luby, Marie, Poole, Karen, Morella, Teresa, Keller, Elizabeth, Benson, Richard T, Lynch, John K, Nadareishvili, Zurab, Hsia, Amie W

“…OBJECTIVE:The objective of this study was to demonstrate the feasibility of timely multimodal MRI screening before thrombolysis in acute stroke patients…”
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Thrombolysis for ischemic stroke in children : Data from the nationwide inpatient sample by JANJUA, Nazli, NASAR, Abu, LYNCH, John K, QURESHI, Adnan I

“…Few pediatric reports of thrombolysis exist. We sought to determine national rates of thrombolysis among pediatric ischemic stroke patients using a national…”
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Stroke in newborn infants by Nelson, Karin B, Lynch, John K

“…The few days before and after birth are a time of special risk for stroke in both mother and infant, probably related to activation of coagulation mechanisms…”
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Identification of Reversible Disruption of the Human Blood–Brain Barrier Following Acute Ischemia by Simpkins, Alexis N, Dias, Christian, Leigh, Richard

“…BACKGROUND AND PURPOSE—Animal models of acute cerebral ischemia have demonstrated that diffuse blood–brain barrier (BBB) disruption can be reversible after…”
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Effects of increasing IV tPA-treated stroke mimic rates at CT-based centers on clinical outcomes by Burton, Tina M, Luby, Marie, Nadareishvili, Zurab, Benson, Richard T, Lynch, John K, Latour, Lawrence L, Hsia, Amie W

“…OBJECTIVE:To determine to what degree stroke mimics skew clinical outcomes and the potential effects of incorrect stroke diagnosis. METHODS:This retrospective…”
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